PTERIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H5N5O
Molecular Weight	163.1368
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NC2=C(N=CC=N2)C(=O)N1

InChI

InChIKey=HNXQXTQTPAJEJL-UHFFFAOYSA-N

InChI=1S/C6H5N5O/c7-6-10-4-3(5(12)11-6)8-1-2-9-4/h1-2H,(H3,7,9,10,11,12)

HIDE SMILES / InChI

Molecular Formula	C6H5N5O
Molecular Weight	163.1368
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Pteridine analysis in urine by capillary electrophoresis using laser-induced fluorescence detection.	1999 Apr 1	10204031
Quod erat demonstrandum? The mystery of experimental validation of apparently erroneous computational analyses of protein sequences.	2001	11790254
Survey of transcripts in the adult Drosophila brain.	2001	11276425
Crystal structure of the 100 kDa arsenite oxidase from Alcaligenes faecalis in two crystal forms at 1.64 A and 2.03 A.	2001 Feb 7	11250197
Involvement of an unusual mol operon in molybdopterin cofactor biosynthesis in Ralstonia eutropha.	2001 Oct	11545279
Reaction of tetrahydrobiopterin with superoxide: EPR-kinetic analysis and characterization of the pteridine radical.	2001 Oct 15	11595382
Crystal structures of human gephyrin and plant Cnx1 G domains: comparative analysis and functional implications.	2001 Sep 14	11554796
Evidence that bacterial cyanide oxygenase is a pterin-dependent hydroxylase.	2001 Sep 21	11554758
Molybdoenzymes and molybdenum cofactor in plants.	2002 Aug	12147719
Screening for tetrahydrobiopterin deficiency among hyperphenylalaninemia patients in Southern China.	2002 Feb	11940335
Oxidation of tetrahydrobiopterin by biological radicals and scavenging of the trihydrobiopterin radical by ascorbate.	2002 Feb 1	11827745
Peroxynitrite enhances the ability of Salmonella dublin to invade T84 monolayers.	2002 Jul	12095142
Fluorescence of pterin, 6-formylpterin, 6-carboxypterin and folic acid in aqueous solution: pH effects.	2002 Jun	12856711
Generation of carbon monoxide and iron from hemeproteins in the presence of 7,8-dihydroneopterin.	2002 Jun 6	12049792
Molecular motions and conformational changes of HPPK.	2002 Nov 1	12211000
Structure of a nitric oxide synthase heme protein from Bacillus subtilis.	2002 Sep 17	12220171
Inhibition of THP-1 cell-mediated low-density lipoprotein oxidation by the macrophage-synthesised pterin, 7,8-dihydroneopterin.	2003	12804014
Mechanistic and mutational studies of Escherichia coli molybdopterin synthase clarify the final step of molybdopterin biosynthesis.	2003 Apr 18	12571226
Single-turnover of nitric-oxide synthase in the presence of 4-amino-tetrahydrobiopterin: proposed role for tetrahydrobiopterin as a proton donor.	2003 Dec 5	14514694
Wavelength-dependent induction of a mycosporine-like amino acid in a rice-field cyanobacterium, Nostoc commune: role of inhibitors and salt stress.	2003 Feb	12664980
Structure of tetrahydrobiopterin tunes its electron transfer to the heme-dioxy intermediate in nitric oxide synthase.	2003 Feb 25	12590583
An extremely potent inhibitor of xanthine oxidoreductase. Crystal structure of the enzyme-inhibitor complex and mechanism of inhibition.	2003 Jan 17	12421831
Physarum polycephalum expresses a dihydropteridine reductase with selectivity for pterin substrates with a 6-(1', 2'-dihydroxypropyl) substitution.	2003 Jul	12956422
Increased folate catabolism following total body gamma-irradiation in mice.	2003 Jun	13678343
Mutations in the molybdenum cofactor biosynthetic genes MOCS1, MOCS2, and GEPH.	2003 Jun	12754701
Studies on the regulatory properties of the pterin cofactor and dopamine bound at the active site of human phenylalanine hydroxylase.	2003 Mar	12603331
Diagnostic chemical shift markers for loop conformation and substrate and cofactor binding in dihydrofolate reductase complexes.	2003 Oct	14500880
Tetrahydrobiopterin prevents nitration of tyrosine hydroxylase by peroxynitrite and nitrogen dioxide.	2003 Oct	14500751
A ruthenium pterin complex showing proton-coupled electron transfer: synthesis and characterization.	2003 Oct 20	14579448
Mechanism of aromatic hydroxylation by an activated FeIV=O core in tetrahydrobiopterin-dependent hydroxylases.	2003 Sep 5	12953191
Inactivation of the Leishmania tarentolae pterin transporter (BT1) and reductase (PTR1) genes leads to viable parasites with changes in folate metabolism and hypersensitivity to the antifolate methotrexate.	2004 Apr 30	14981076
Redox reactions of the pyranopterin system of the molybdenum cofactor.	2004 Jan	14628171

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:49:42 GMT 2023` Edited by `admin` on `Fri Dec 15 19:49:42 GMT 2023`
Record UNII	85MA24E1NH
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PTERIN

Common Name

English

NSC-11540

Code

English

PTERIDOXAMINE

Common Name

English

NSC-18696

Code

English

2-AMINO-4-HYDROXYPTERIDINE

Systematic Name

English

2-AMINO-4-PTERIDONE

Systematic Name

English

NSC-170929

Code

English

Classification Tree Code System Code

LOINC

80166-2