POVIDONE-IODINE

US Approved OTC

First marketed in 1921

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7829615 | https://www.ncbi.nlm.nih.gov/pubmed/22137863 | http://www.potableaqua.com/

Tetraglycine hydroperiodide is an iodine-containing chemical, used for water purification. Tetraglycine hydroperiodide is marketed in tablets; each tablet effectively disinfects 1 liter of clear water or 0.5 liter of tainted water by releasing approximately 8 mg free iodine. It requires approximately 30 minutes to inactivate target microorganisms and make water bacteriologically suitable for drinking. To remove iodine taste, a vitamin C pill is added to the kit.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
antiseptic 6 Sources: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=74a2cbd9-a16f-4819-a45d-3efc2f23c071	Primary		Approved 8429	Surgicide Approved Use Surgicide is a broad spectrum topical antiseptic for use on skin and mucous membranes. Use solution without dilution as needed

PubMed

Title	Date	PubMed
[Necrotizing hepatitis with a fatal outcome after carbimazole therapy].	1993 Oct 22	8223196
Subfulminant hepatitis requiring liver transplantation after benzarone administration.	1994 Jun	7930488
Case report: reversible mitral regurgitation and congestive heart failure complicating thyrotoxicosis.	1996 Mar	8615390
Adverse reactions to nonionic iodine in contrast-enhanced computed tomography: usefulness of monitoring vital signs.	1998 Jul	9780895
Thyrotropin-secreting pituitary adenoma responsive to bromocriptine therapy.	1999 Sep-Oct	15251663
Anti-goitrous effect of lecithin-bound iodine in propylthiouracil treated rats.	2000 Jun	10911406
Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard-induced skin.	2001 Feb	11305779
Effects of selenium and iodine on c-fos and c-jun mRNA and their protein expressions in cultured rat hippocampus cells.	2002 Winter	12666833
Synergistic interaction between excess caffeine and deficient iodine on the promotion of thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl)nitrosamine.	2003 Apr	12824900
Functional expression of sodium iodide symporter (NIS) in human breast cancer tissue.	2003 Jan	12602914
[Effect of high-iodine intake on MBP mRNA expression in cerebrum of filial mice and selenium intervention].	2005 Jul	16229266
Inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis by molecular iodine (I2) but not by iodide (I-) treatment Evidence that I2 prevents cancer promotion.	2005 May 31	15922087
Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation.	2006 Aug 1	16514648
Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway.	2006 Jul 14	16679319
Use of gadolinium for carotid artery angiography and stenting in patients with renal insufficiency.	2009 Dec	19909415
A blinded, randomized, palatability study comparing variations of 2 popular field water disinfection tablets.	2011 Dec	22137863
The effects of ammonium perchlorate on thyroid homeostasis and thyroid-specific gene expression in rat.	2012 Aug	20882593
Sensitivity of human dental pulp cells to eighteen chemical agents used for endodontic treatments in dentistry.	2013 Jan	22083529
Developmental iodine deficiency delays the maturation of newborn granule neurons associated with downregulation of p35 in postnatal rat hippocampus.	2014 Aug	22987596

Patents

Substance Class	Mixture Created by `admin` on `Fri Dec 15 16:00:46 UTC 2023` Edited by `admin` on `Fri Dec 15 16:00:46 UTC 2023`
Record UNII	85H0HZU99M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

POVIDONE-IODINE

Common Name

English

BETADINE

Brand Name

English

2-PYRROLIDINONE, 1-ETHENYL-, HOMOPOLYMER, COMPD. WITH IODINE

Common Name

English

POVIDONE-IODINE [MART.]

Common Name

English

E-Z PREP 220

Brand Name

English

POVIDONE IODINE [VANDF]

Common Name

English

E-Z PREP

Brand Name

English

PVP-IODINE [INCI]

Common Name

English

Povidone-iodine [WHO-DD]

Common Name

English

E-Z SCRUB 201

Brand Name

English

POVIDONE-IODINE [VANDF]

Common Name

English

POVIDONE-IODINE [HSDB]

Common Name

English

POVIDONE-IODINE [ORANGE BOOK]

Common Name

English

PVP-IODINE

Official Name

English

E-Z SCRUB 241

Brand Name

English

1-Vinyl-2-pyrrolidinone polymer, compound with iodine

Common Name

English

POVIDONE-IODINE [JAN]

Common Name

English

NSC-26245

Code

English

POVIDONE-IODINE [MI]

Common Name

English

POVIDONE IODINE

Common Name

English

POVIDONE-IODINE [USP MONOGRAPH]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QG51AD01

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

WHO-VATC

QD08AG02

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

NDF-RT

N0000007196

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

WHO-ATC

G01AX11

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

WHO-VATC

QD11AC06

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

WHO-ATC

S01AX18

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

FDA ORPHAN DRUG

564916

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

WHO-ATC

R02AA15

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

FDA ORPHAN DRUG

566216

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

WHO-ATC

D11AC06

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

NDF-RT

N0000175486

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

WHO-ATC

D08AG02

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

NCI_THESAURUS

C254

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

WHO-VATC

QS01AX18

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

CFR

21 CFR 333.210

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

FDA ORPHAN DRUG

647518

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

WHO-VATC

QG01AX11

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

WHO-VATC

QD09AA09

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

WHO-ATC

D09AA09

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

EPA PESTICIDE CODE

46914

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

WHO-VATC

QR02AA15

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

Code System Code Type Description

DAILYMED

85H0HZU99M

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

PRIMARY

NSC

26245

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

PRIMARY

EPA CompTox

DTXSID8035712

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

PRIMARY

ChEMBL

CHEMBL1201724

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

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WIKIPEDIA

POVIDONE-IODINE

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

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LACTMED

Povidone-Iodine

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

PRIMARY

DRUG CENTRAL

4249

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

PRIMARY

MERCK INDEX

m9085

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

PRIMARY

Merck Index

DRUG BANK

DB06812

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

PRIMARY

NCI_THESAURUS

C766

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

PRIMARY

HSDB

6831

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

PRIMARY

MESH

D011206

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

PRIMARY

RXCUI

8611

Created by admin on Fri Dec 15 16:00:47 UTC 2023 , Edited by admin on Fri Dec 15 16:00:47 UTC 2023

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RxNorm

FDA UNII

85H0HZU99M

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

PRIMARY

EVMPD

SUB14999MIG

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

PRIMARY

CAS

25655-41-8

Created by admin on Fri Dec 15 16:00:46 UTC 2023 , Edited by admin on Fri Dec 15 16:00:46 UTC 2023

PRIMARY

All of the following components must be present:


					FZ989GH94E

POVIDONE, UNSPECIFIED


					9679TC07X4

Iodine

Related Record Type Details


					9679TC07X4

Iodine

ACTIVE MOIETY

DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/7829615 | https://www.ncbi.nlm.nih.gov/pubmed/22137863 | http://www.potableaqua.com/

Approval Year

Conditions

Approved Use

PubMed

Patents

All of the following components must be present:

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7829615 | https://www.ncbi.nlm.nih.gov/pubmed/22137863 | http://www.potableaqua.com/