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Description

Tetraglycine hydroperiodide is an iodine-containing chemical, used for water purification. Tetraglycine hydroperiodide is marketed in tablets; each tablet effectively disinfects 1 liter of clear water or 0.5 liter of tainted water by releasing approximately 8 mg free iodine. It requires approximately 30 minutes to inactivate target microorganisms and make water bacteriologically suitable for drinking. To remove iodine taste, a vitamin C pill is added to the kit.

Approval Year

1921
1467
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Approved
8429
Surgicide

Approved Use

Surgicide is a broad spectrum topical antiseptic for use on skin and mucous membranes. Use solution without dilution as needed
PubMed

PubMed

TitleDatePubMed
The susceptibility of the fetus and child to chemical pollutants. Special susceptibility of the host to chemical agents: endocrinologic considerations.
1974 May
Case report: reversible mitral regurgitation and congestive heart failure complicating thyrotoxicosis.
1996 Mar
Thyrotropin-secreting pituitary adenoma responsive to bromocriptine therapy.
1999 Sep-Oct
Anti-goitrous effect of lecithin-bound iodine in propylthiouracil treated rats.
2000 Jun
Effects of iodine on inducible nitric oxide synthase and cyclooxygenase-2 expression in sulfur mustard-induced skin.
2001 Feb
Effects of selenium and iodine on the expression of c-fos and c-jun mRNA and their proteins in cultured rat hippocampus neurons.
2002 Jun
Synergistic interaction between excess caffeine and deficient iodine on the promotion of thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl)nitrosamine.
2003 Apr
Inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis by molecular iodine (I2) but not by iodide (I-) treatment Evidence that I2 prevents cancer promotion.
2005 May 31
Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway.
2006 Jul 14
Antiseptics, iodine, povidone iodine and traumatic wound cleansing.
2006 Nov
The treatment of Graves' disease in children.
2006 Sep
[Effects of iodine excess and selenium supplement on the levels of thyroid hormone and its receptor expression in filial cerebrum of mice].
2007 Mar
Enhanced expression of adenovirus-mediated sodium iodide symporter gene in MCF-7 breast cancer cells with retinoic acid treatment.
2007 Mar
[The effects of iodine/selenium on the function of antigen presentation of peritoneal macrophages in rats].
2008 Jul
Gadolinium and kidney disease: are your patients at risk?
2008 Mar-Apr
Use of gadolinium for carotid artery angiography and stenting in patients with renal insufficiency.
2009 Dec
A blinded, randomized, palatability study comparing variations of 2 popular field water disinfection tablets.
2011 Dec
Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice.
2012 Sep 1
Developmental iodine deficiency delays the maturation of newborn granule neurons associated with downregulation of p35 in postnatal rat hippocampus.
2014 Aug
Patents

Patents

20030153532
9
Substance Class Mixture
Created
by admin
on Fri Dec 15 16:00:46 GMT 2023
Edited
by admin
on Fri Dec 15 16:00:46 GMT 2023
Record UNII
85H0HZU99M
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
POVIDONE-IODINE
HSDB   MART.   MI   ORANGE BOOK   USP   VANDF   WHO-DD  
Common Name English
BETADINE
Brand Name English
2-PYRROLIDINONE, 1-ETHENYL-, HOMOPOLYMER, COMPD. WITH IODINE
Common Name English
POVIDONE-IODINE [MART.]
Common Name English
E-Z PREP 220
Brand Name English
POVIDONE IODINE [VANDF]
Common Name English
E-Z PREP
Brand Name English
PVP-IODINE [INCI]
Common Name English
Povidone-iodine [WHO-DD]
Common Name English
E-Z SCRUB 201
Brand Name English
POVIDONE-IODINE [VANDF]
Common Name English
POVIDONE-IODINE [HSDB]
Common Name English
POVIDONE-IODINE [ORANGE BOOK]
Common Name English
PVP-IODINE
INCI  
INCI  
Official Name English
E-Z SCRUB 241
Brand Name English
1-Vinyl-2-pyrrolidinone polymer, compound with iodine
Common Name English
POVIDONE-IODINE [JAN]
Common Name English
NSC-26245
Code English
POVIDONE-IODINE [MI]
Common Name English
POVIDONE IODINE
VANDF  
Common Name English
POVIDONE-IODINE [USP MONOGRAPH]
Common Name English
Classification Tree Code System Code
WHO-VATC QG51AD01
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
WHO-VATC QD08AG02
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
NDF-RT N0000007196
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
WHO-ATC G01AX11
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
WHO-VATC QD11AC06
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
WHO-ATC S01AX18
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
FDA ORPHAN DRUG 564916
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
WHO-ATC R02AA15
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
FDA ORPHAN DRUG 566216
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
WHO-ATC D11AC06
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
NDF-RT N0000175486
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
WHO-ATC D08AG02
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
NCI_THESAURUS C254
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
WHO-VATC QS01AX18
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
CFR 21 CFR 333.210
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
FDA ORPHAN DRUG 647518
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
WHO-VATC QG01AX11
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
WHO-VATC QD09AA09
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
WHO-ATC D09AA09
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
EPA PESTICIDE CODE 46914
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
WHO-VATC QR02AA15
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
Code System Code Type Description
DAILYMED
85H0HZU99M
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
PRIMARY
NSC
26245
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
PRIMARY
EPA CompTox
DTXSID8035712
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
PRIMARY
ChEMBL
CHEMBL1201724
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
PRIMARY
WIKIPEDIA
POVIDONE-IODINE
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
PRIMARY
LACTMED
Povidone-Iodine
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
PRIMARY
DRUG CENTRAL
4249
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
PRIMARY
MERCK INDEX
m9085
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
PRIMARY Merck Index
DRUG BANK
DB06812
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
PRIMARY
NCI_THESAURUS
C766
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
PRIMARY
HSDB
6831
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
PRIMARY
MESH
D011206
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
PRIMARY
RXCUI
8611
Created by admin on Fri Dec 15 16:00:47 GMT 2023 , Edited by admin on Fri Dec 15 16:00:47 GMT 2023
PRIMARY RxNorm
FDA UNII
85H0HZU99M
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
PRIMARY
EVMPD
SUB14999MIG
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
PRIMARY
CAS
25655-41-8
Created by admin on Fri Dec 15 16:00:46 GMT 2023 , Edited by admin on Fri Dec 15 16:00:46 GMT 2023
PRIMARY
All of the following components must be present:
POVIDONE, UNSPECIFIED
Structure of Iodine
Related Record Type Details
Structure of Iodine
ACTIVE MOIETY
Definition References
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966