FDU-PB-22

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C26H18FNO2
Molecular Weight	395.425
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of FDU-PB-22

Structure Search

SMILES

FC1=CC=C(CN2C=C(C(=O)OC3=CC=CC4=C3C=CC=C4)C5=C2C=CC=C5)C=C1

InChI

InChIKey=RCEKSVIFQKKFLS-UHFFFAOYSA-N

InChI=1S/C26H18FNO2/c27-20-14-12-18(13-15-20)16-28-17-23(22-9-3-4-10-24(22)28)26(29)30-25-11-5-7-19-6-1-2-8-21(19)25/h1-15,17H,16H2

HIDE SMILES / InChI

Molecular Formula	C26H18FNO2
Molecular Weight	395.425
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Cannabinoid receptor 1 30 Target ID: P21554\|\|\|Q5UB37 Gene ID: 1268.0 Gene Symbol: CNR1 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/27429655	Agonist 2678		1.19 nM [Ki]
Cannabinoid receptor 2 27 Target ID: P34972 Gene ID: 1269.0 Gene Symbol: CNR2 Target Organism: Homo sapiens (Human) Sources: https://www.ncbi.nlm.nih.gov/pubmed/27429655	Agonist 2678		2.43 nM [Ki]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:40:03 UTC 2023` Edited by `admin` on `Sat Dec 16 10:40:03 UTC 2023`
Record UNII	85E88884ZQ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

FDU-PB-22

Common Name

English

1H-INDOLE-3-CARBOXYLIC ACID, 1-((4-FLUOROPHENYL)METHYL)-, 1-NAPHTHALENYL ESTER

Systematic Name

English

NAPHTHALEN-1-YL 1-((4-FLUOROPHENYL)METHYL)-1H-INDOLE-3-CARBOXYLATE

Systematic Name

English

1-((4-FLUOROPHENYL)METHYL)-1H-INDOLE-3-CARBOXYLIC ACID, 1-NAPHTHALENYL ESTER

Systematic Name

English

Classification Tree Code System Code

WIKIPEDIA

Designer-drugs-FDU-PB-22

Created by admin on Sat Dec 16 10:40:03 UTC 2023 , Edited by admin on Sat Dec 16 10:40:03 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID90101691

Created by admin on Sat Dec 16 10:40:03 UTC 2023 , Edited by admin on Sat Dec 16 10:40:03 UTC 2023

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MANUFACTURER PRODUCT INFORMATION

FDU-PB-22

Created by admin on Sat Dec 16 10:40:03 UTC 2023 , Edited by admin on Sat Dec 16 10:40:03 UTC 2023

PRIMARY

Several cannabimimetic quinolinyl carboxylates (PB-22, Item No. 14096 and BB-22, Item No. 14099) and cannabimimetic carboxamide derivatives (ADB-FUBINACA, Item No. 14292 and ADBICA, Item No. 14293) have been identified as designer drugs in illegal products.1 FDU-PB-22 is a derivative of PB-22 in which the pentyl side chain is replaced by a 4-fluorobenzyl group, a functional group also found in indazole-based synthetic cannabinoids such as ADB-FUBINACA. Additionally, the 8-quinolinol is replaced by a naphthalene group, similar to the structure of AM2201 (Item No. 10707).2,3,1 The physiological and toxicological properties of this compound are not known.

CAS

1883284-94-3

Created by admin on Sat Dec 16 10:40:03 UTC 2023 , Edited by admin on Sat Dec 16 10:40:03 UTC 2023

PRIMARY

WIKIPEDIA

FDU-PB-22

Created by admin on Sat Dec 16 10:40:03 UTC 2023 , Edited by admin on Sat Dec 16 10:40:03 UTC 2023

PRIMARY

FDU-PB-22 is an derivative of JWH-018 that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a "legal high". FDU-PB-22 is a controlled substance in Germany and is banned in Japan and Sweden.

PUBCHEM

119025888

Created by admin on Sat Dec 16 10:40:03 UTC 2023 , Edited by admin on Sat Dec 16 10:40:03 UTC 2023

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FDA UNII

85E88884ZQ

Created by admin on Sat Dec 16 10:40:03 UTC 2023 , Edited by admin on Sat Dec 16 10:40:03 UTC 2023

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Related Record Type Details


					85E88884ZQ

FDU-PB-22

ACTIVE MOIETY