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Details

Stereochemistry ACHIRAL
Molecular Formula C6H16N2
Molecular Weight 116.2046
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N,N-DIETHYLETHYLENEDIAMINE

SMILES

CCN(CC)CCN

InChI

InChIKey=UDGSVBYJWHOHNN-UHFFFAOYSA-N
InChI=1S/C6H16N2/c1-3-8(4-2)6-5-7/h3-7H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C6H16N2
Molecular Weight 116.2046
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

N,N-Diethylethylenediamine is used in the oxidative amidation of hydrogen phosphonate diesters in the synthesis of oligonucleotides. N,N-diethylethylenediamine was used to develop melanin targeted PET and single-photon emission computed tomography (SPECT) imaging agents for melanoma.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Chromosome targeting at short polypurine sites by cationic triplex-forming oligonucleotides.
2001 Oct 19
Unusually long-lived light-induced metastable state in a thermochromic copper(II) complex.
2002 Aug 7
Water-soluble polycationic dendrimers with a phosphoramidothioate backbone: preliminary studies of cytotoxicity and oligonucleotide/plasmid delivery in human cell culture.
2003
Anionic carbonato and oxalato cobalt(III) nitrogen mustard complexes.
2004 Feb 21
Platelet adhesive resistance of polyurethane surface grafted with zwitterions of sulfobetaine.
2004 Jul 1
Design of amine-modified graft polyesters for effective gene delivery using DNA-loaded nanoparticles.
2004 Jun
Liquid chromatographic determination of ethambutol in serum samples based on intramolecular excimer-forming fluorescence derivatization.
2004 Mar
Alkylating benzamides with melanoma cytotoxicity.
2004 Oct
Synthesis of novel biodegradable cationic polymer: N,N-diethylethylenediamine polyurethane as a gene carrier.
2004 Sep-Oct
Distance and affinity dependence of triplex-induced recombination.
2005 Mar 15
Antisense knockdown of cyclin E does not affect the midblastula transition in Xenopus laevis embryos.
2005 Oct
Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds.
2006 Mar
Tubular cationized pullulan hydrogels as local reservoirs for plasmid DNA.
2007 Dec 1
Di-μ-thio-cyanato-bis-({2,4-dichloro-6-[2-(diethyl-amino)ethyl-imino-meth-yl]phenolato}copper(II)).
2007 Dec 18
Polyamine-substituted gadolinium chelates: a new class of intracellular contrast agents for magnetic resonance imaging of tumors.
2007 Jan 11
Synthesis and antimalarial properties of new chloro-9H-xanthones with an aminoalkyl side chain.
2007 Jul
Stability-indicating methods for determination of tiapride in pure form, pharmaceutical preparation, and human plasma.
2007 Nov-Dec
Antiproliferative effects on human tumor cells and rat aortic smooth muscular cells of 2,3-heteroarylmaleimides and heterofused imides.
2008 Feb 15
The prince and the pauper. A tale of anticancer targeted agents.
2008 Oct 23
Equilibrium and kinetic investigations of the interaction of model platinum(II) complex with DNA constituents in reference to the antitumour activity: complex-formation reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with ligands of biological significance and displacement reactions of DNA constituents.
2009
Benzamides as melanotropic carriers for radioisotopes, metals, cytotoxic agents and as enzyme inhibitors.
2009
trans-Bis(N,N-diethyl-ethylenediamine)-nickel(II) dibromide.
2010 Dec 8
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
Preparation of N-(2-diethylaminoethyl)-4-fluorobenzamide (DAFBA): A solution of N,N-diethylethylenediamine (1.0 g, 8.6 mmol) in dichloromethane (10 mL) was added slowly to the reaction mixture.
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:05:01 GMT 2023
Edited
by admin
on Sat Dec 16 08:05:01 GMT 2023
Record UNII
859V6OK12Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
N,N-DIETHYLETHYLENEDIAMINE
Systematic Name English
TIAPRIDE HYDROCHLORIDE IMPURITY C [EP IMPURITY]
Common Name English
.BETA.-(DIETHYLAMINO)ETHYLAMINE
Systematic Name English
N-(2-(N,N-DIETHYLAMINO)ETHYL)AMINE
Systematic Name English
1,2-ETHANEDIAMINE, N1,N1-DIETHYL-
Systematic Name English
N,N-DIETHYL-1,2-DIAMINOETHANE
Systematic Name English
METOCLOPRAMIDE IMPURITY E [EP IMPURITY]
Common Name English
N,N-DIETHYL-1,2-ETHYLENEDIAMINE
Systematic Name English
N,N-DIETHYLETHANE-1,2-DIAMINE
Systematic Name English
NSC-19675
Code English
Code System Code Type Description
ECHA (EC/EINECS)
202-844-7
Created by admin on Sat Dec 16 08:05:02 GMT 2023 , Edited by admin on Sat Dec 16 08:05:02 GMT 2023
PRIMARY
NSC
19675
Created by admin on Sat Dec 16 08:05:02 GMT 2023 , Edited by admin on Sat Dec 16 08:05:02 GMT 2023
PRIMARY
PUBCHEM
60993
Created by admin on Sat Dec 16 08:05:02 GMT 2023 , Edited by admin on Sat Dec 16 08:05:02 GMT 2023
PRIMARY
CAS
100-36-7
Created by admin on Sat Dec 16 08:05:02 GMT 2023 , Edited by admin on Sat Dec 16 08:05:02 GMT 2023
PRIMARY
EPA CompTox
DTXSID7057606
Created by admin on Sat Dec 16 08:05:02 GMT 2023 , Edited by admin on Sat Dec 16 08:05:02 GMT 2023
PRIMARY
FDA UNII
859V6OK12Y
Created by admin on Sat Dec 16 08:05:02 GMT 2023 , Edited by admin on Sat Dec 16 08:05:02 GMT 2023
PRIMARY
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PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (TLC)
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