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Details

Stereochemistry ACHIRAL
Molecular Formula C6H16N2
Molecular Weight 116.2046
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N,N-DIETHYLETHYLENEDIAMINE

SMILES

CCN(CC)CCN

InChI

InChIKey=UDGSVBYJWHOHNN-UHFFFAOYSA-N
InChI=1S/C6H16N2/c1-3-8(4-2)6-5-7/h3-7H2,1-2H3

HIDE SMILES / InChI
Molecular Formula C6H16N2
Molecular Weight 116.2046
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

N,N-Diethylethylenediamine is used in the oxidative amidation of hydrogen phosphonate diesters in the synthesis of oligonucleotides. N,N-diethylethylenediamine was used to develop melanin targeted PET and single-photon emission computed tomography (SPECT) imaging agents for melanoma.

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Diagnostic
Basic research
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Unusually long-lived light-induced metastable state in a thermochromic copper(II) complex.
2002 Aug 7
Anionic carbonato and oxalato cobalt(III) nitrogen mustard complexes.
2004 Feb 21
Alkylating benzamides with melanoma cytotoxicity.
2004 Oct
Synthesis of novel biodegradable cationic polymer: N,N-diethylethylenediamine polyurethane as a gene carrier.
2004 Sep-Oct
Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds.
2006 Mar
Tubular cationized pullulan hydrogels as local reservoirs for plasmid DNA.
2007 Dec 1
Di-μ-thio-cyanato-bis-({2,4-dichloro-6-[2-(diethyl-amino)ethyl-imino-meth-yl]phenolato}copper(II)).
2007 Dec 18
Polyamine-substituted gadolinium chelates: a new class of intracellular contrast agents for magnetic resonance imaging of tumors.
2007 Jan 11
Synthesis and antimalarial properties of new chloro-9H-xanthones with an aminoalkyl side chain.
2007 Jul
Stability-indicating methods for determination of tiapride in pure form, pharmaceutical preparation, and human plasma.
2007 Nov-Dec
Antiproliferative effects on human tumor cells and rat aortic smooth muscular cells of 2,3-heteroarylmaleimides and heterofused imides.
2008 Feb 15
The prince and the pauper. A tale of anticancer targeted agents.
2008 Oct 23
Equilibrium and kinetic investigations of the interaction of model platinum(II) complex with DNA constituents in reference to the antitumour activity: complex-formation reactions of [Pd(N,N-diethylethylenediamine)(H2O)2]2+ with ligands of biological significance and displacement reactions of DNA constituents.
2009
Benzamides as melanotropic carriers for radioisotopes, metals, cytotoxic agents and as enzyme inhibitors.
2009
trans-Bis(N,N-diethyl-ethylenediamine)-nickel(II) dibromide.
2010 Dec 8
Patents

Patents

03996374
5
04014878
3
04186135
2
04215216
2
04296114
1
04301281
2
04582851
1
04597902
1
04640920
3
05382585
1
05955607
1
06642231
4
07232902
1
07550454
1
07572924
2
07754713
2
08173656
1
08822503
4
JPS5616453A
1

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Preparation of N-(2-diethylaminoethyl)-4-fluorobenzamide (DAFBA): A solution of N,N-diethylethylenediamine (1.0 g, 8.6 mmol) in dichloromethane (10 mL) was added slowly to the reaction mixture.
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:05:01 UTC 2023
Edited
by admin
on Sat Dec 16 08:05:01 UTC 2023
Record UNII
859V6OK12Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
N,N-DIETHYLETHYLENEDIAMINE
Systematic Name English
TIAPRIDE HYDROCHLORIDE IMPURITY C [EP IMPURITY]
Common Name English
.BETA.-(DIETHYLAMINO)ETHYLAMINE
Systematic Name English
N-(2-(N,N-DIETHYLAMINO)ETHYL)AMINE
Systematic Name English
1,2-ETHANEDIAMINE, N1,N1-DIETHYL-
Systematic Name English
N,N-DIETHYL-1,2-DIAMINOETHANE
Systematic Name English
METOCLOPRAMIDE IMPURITY E [EP IMPURITY]
Common Name English
N,N-DIETHYL-1,2-ETHYLENEDIAMINE
Systematic Name English
N,N-DIETHYLETHANE-1,2-DIAMINE
Systematic Name English
NSC-19675
Code English
Code System Code Type Description
ECHA (EC/EINECS)
202-844-7
Created by admin on Sat Dec 16 08:05:02 UTC 2023 , Edited by admin on Sat Dec 16 08:05:02 UTC 2023
PRIMARY
NSC
19675
Created by admin on Sat Dec 16 08:05:02 UTC 2023 , Edited by admin on Sat Dec 16 08:05:02 UTC 2023
PRIMARY
PUBCHEM
60993
Created by admin on Sat Dec 16 08:05:02 UTC 2023 , Edited by admin on Sat Dec 16 08:05:02 UTC 2023
PRIMARY
CAS
100-36-7
Created by admin on Sat Dec 16 08:05:02 UTC 2023 , Edited by admin on Sat Dec 16 08:05:02 UTC 2023
PRIMARY
EPA CompTox
DTXSID7057606
Created by admin on Sat Dec 16 08:05:02 UTC 2023 , Edited by admin on Sat Dec 16 08:05:02 UTC 2023
PRIMARY
FDA UNII
859V6OK12Y
Created by admin on Sat Dec 16 08:05:02 UTC 2023 , Edited by admin on Sat Dec 16 08:05:02 UTC 2023
PRIMARY
Related Record Type Details
Structure of METOCLOPRAMIDE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (TLC)
EP
Structure of TIAPRIDE HYDROCHLORIDE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (TLC)
EP
Structure of METOCLOPRAMIDE HYDROCHLORIDE
PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (TLC)
EP
NIH
NCATS
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