TECTORIGENIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H12O6
Molecular Weight	300.2629
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(O)C2=C(OC=C(C2=O)C3=CC=C(O)C=C3)C=C1O

InChI

InChIKey=OBBCRPUNCUPUOS-UHFFFAOYSA-N

InChI=1S/C16H12O6/c1-21-16-11(18)6-12-13(15(16)20)14(19)10(7-22-12)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3

HIDE SMILES / InChI

Molecular Formula	C16H12O6
Molecular Weight	300.2629
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Isoflavonoid glycosides from Dalbergia sissoo.	2001 Aug	11454356
Tectorigenin, an isoflavone of Pueraria thunbergiana Benth., induces differentiation and apoptosis in human promyelocytic leukemia HL-60 cells.	2001 Oct	11642314
Effects of naturally occurring isoflavones on prostaglandin E2 production.	2002 Feb	11859455
Potent antimutagenic and their anti-lipid peroxidative effect of kaikasaponin III and tectorigenin from the flower of Pueraria thunbergiana.	2002 Jun	12135104
Study of substance changes in flowers of Pueraria thunbergiana Benth. during storage.	2003 Mar	12723934
Phytoestrogens derived from Belamcanda chinensis have an antiproliferative effect on prostate cancer cells in vitro.	2004 Dec	15538285
Passive cutaneous anaphylaxis-inhibitory action of tectorigenin, a metabolite of tectoridin by intestinal microflora.	2004 Jul	15256747
Hepatoprotective effect of tectoridin and tectorigenin on tert-butyl hyperoxide-induced liver injury.	2005 Apr	15821336
Tectorigenin and other phytochemicals extracted from leopard lily Belamcanda chinensis affect new and established targets for therapies in prostate cancer.	2005 Aug	15845653
Phenolic constituents of the rhizomes of the Thai medicinal plant Belamcanda chinensis with proliferative activity for two breast cancer cell lines.	2005 Mar	15787436
Lead compounds for anti-inflammatory drugs isolated from the plants of the traditional oriental medicine in Korea.	2008 Sep	18782027
Identification of the major metabolites of tectorigenin in rat bile by liquid chromatography combined with time-of-flight and ion trap tandem mass spectrometry.	2008 Sep	18668634
Quantitative analysis of two isoflavones in Pueraria lobata flowers from eleven Chinese provinces using high performance liquid chromatography.	2010 Apr 23	20416072
Tyrosinase inhibitory constituents from the stems of Maackia fauriei.	2010 Jan	19441007

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 02:27:46 GMT 2023` Edited by `admin` on `Sat Dec 16 02:27:46 GMT 2023`
Record UNII	855130H9CO
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TECTORIGENIN

Common Name

English

4',5,7-TRIHYDROXY-6-METHOXYISOFLAVONE

Common Name

English

TECTORIGENIN [MI]

Common Name

English

K 251T

Code

English

5,7-DIHYDROXY-3-(4-HYDROXYPHENYL)-6-METHOXY-4H-1-BENZOPYRAN-4-ONE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1745