TECTORIGENIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C16H12O6
Molecular Weight	300.2629
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=C(O)C2=C(OC=C(C2=O)C3=CC=C(O)C=C3)C=C1O

InChI

InChIKey=OBBCRPUNCUPUOS-UHFFFAOYSA-N

InChI=1S/C16H12O6/c1-21-16-11(18)6-12-13(15(16)20)14(19)10(7-22-12)8-2-4-9(17)5-3-8/h2-7,17-18,20H,1H3

HIDE SMILES / InChI

Molecular Formula	C16H12O6
Molecular Weight	300.2629
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
[Studies on chemical constituents of Maackia amurensis Rupr. et. Maxim].	2001 Jun	12528507
Effects of naturally occurring isoflavones on prostaglandin E2 production.	2002 Feb	11859455
Isoflavonoids from the rhizomes of Belamcanda chinensis and their effects on aldose reductase and sorbitol accumulation in streptozotocin induced diabetic rat tissues.	2002 Jun	12135102
Antiplatelet and anti-HIV constituents from Euchresta formosana.	2003 Apr	12713120
Phytoestrogens derived from Belamcanda chinensis have an antiproliferative effect on prostate cancer cells in vitro.	2004 Dec	15538285
Induction of growth hormone release by Pueraria thunbergiana BENTH.	2004 Feb	15002057
Analysis of DNA in endometrial cancer cells treated with phyto-estrogenic compounds using comparative genomic hybridisation microarrays.	2005 May	15931582
Cytoprotective effect of tectorigenin, a metabolite formed by transformation of tectoridin by intestinal microflora, on oxidative stress induced by hydrogen peroxide.	2005 Sep 5	16102749
Identification of metabolites of tectoridin in-vivo and in-vitro by liquid chromatography-tandem mass spectrometry.	2008 Jun	18498706
The rapid identification of isoflavonoids from Belamcanda chinensis by LC-NMR and LC-MS.	2008 Oct	18827388
Identification of key metabolites of tectorigenin in rat urine by HPLC-MS(n).	2009 Feb	18850580
New isoflavone glycosides from Iris spuria L. (Calizona) cultivated in Egypt.	2009 Jan	18791667
Isolation and purification of isoflavonoids from Rhizoma Belamcandae by two-dimensional preparative high-performance liquid chromatography with column switch technology.	2009 Oct	19382246
Tectorigenin inhibits the in vitro proliferation and enhances miR-338* expression of pulmonary fibroblasts in rats with idiopathic pulmonary fibrosis.	2010 Aug 19	20600766
Anti-proliferative and pro-apoptotic effects of tectorigenin on hepatic stellate cells.	2010 Aug 21	20712052
Isolation and identification of urinary metabolites of kakkalide in rats.	2010 Feb	19910516
Tyrosinase inhibitory constituents from the stems of Maackia fauriei.	2010 Jan	19441007
[Simultaneous determination of tectorigenin-7-O-xylosylglucosid, tectoridin and tectorigenin in flowers of Pueraria lobata by HPLC].	2010 Sep	21137344
Yeast α-glucosidase inhibition by isoflavones from plants of Leguminosae as an in vitro alternative to acarbose.	2010 Sep 22	20734984

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 02:27:46 GMT 2023` Edited by `admin` on `Sat Dec 16 02:27:46 GMT 2023`
Record UNII	855130H9CO
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TECTORIGENIN

Common Name

English

4',5,7-TRIHYDROXY-6-METHOXYISOFLAVONE

Common Name

English

TECTORIGENIN [MI]

Common Name

English

K 251T

Code

English

5,7-DIHYDROXY-3-(4-HYDROXYPHENYL)-6-METHOXY-4H-1-BENZOPYRAN-4-ONE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1745