U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C21H28O4
Molecular Weight 344.4446
Optical Activity UNSPECIFIED
Defined Stereocenters 6 / 6
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 7-OXODEHYDROEPIANDROSTERONE 3-ACETATE

SMILES

[H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]3([H])[C@@]2([H])C(=O)C=C4C[C@H](CC[C@]34C)OC(C)=O

InChI

InChIKey=VVSMJVQHDZUPIL-XFKPDKBWSA-N
InChI=1S/C21H28O4/c1-12(22)25-14-6-8-20(2)13(10-14)11-17(23)19-15-4-5-18(24)21(15,3)9-7-16(19)20/h11,14-16,19H,4-10H2,1-3H3/t14-,15-,16-,19-,20-,21-/m0/s1

HIDE SMILES / InChI

Molecular Formula C21H28O4
Molecular Weight 344.4446
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 6 / 6
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
[Effects of 7-oxo-DHEA treatment on the immunoreactivity of BALB/c mice subjected to chronic mild stress].
2003 Dec
Steroids and thermogenesis.
2006
How short-term transdermal treatment of men with 7-oxo-dehydroepiandrosterone influence thyroid function.
2006
A novel radioimmunoassay of 7-oxo-DHEA and its physiological levels.
2007 Apr
Dehydroepiandrosterone 7alpha-hydroxylation in human tissues: possible interference with type 1 11beta-hydroxysteroid dehydrogenase-mediated processes.
2007 May
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:28:56 GMT 2023
Edited
by admin
on Sat Dec 16 08:28:56 GMT 2023
Record UNII
84RQ0XOM11
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
7-OXODEHYDROEPIANDROSTERONE 3-ACETATE
Common Name English
7-OXO-DHEA-ACETATE
Common Name English
J793.891H
Code English
NSC-134911
Code English
ANDROST-5-ENE-7,17-DIONE, 3.BETA.-HYDROXY-, ACETATE
Systematic Name English
ANDROST-5-ENE-7,17-DIONE, 3-(ACETYLOXY)-, (3.BETA.)-
Systematic Name English
7-KETO-DEHYDROEPIANDROSTERONE ACETATE
Common Name English
7-keto-dehydroepiandrosterone acetate [WHO-DD]
Common Name English
7-KETO NATURALEAN
Common Name English
3.BETA.-ACETOXYANDROST-5-ENE-7,17-DIONE
Systematic Name English
7-OXODEHYDROEPIANDROSTERONE ACETATE
Common Name English
Code System Code Type Description
FDA UNII
84RQ0XOM11
Created by admin on Sat Dec 16 08:28:56 GMT 2023 , Edited by admin on Sat Dec 16 08:28:56 GMT 2023
PRIMARY
RXCUI
1747869
Created by admin on Sat Dec 16 08:28:56 GMT 2023 , Edited by admin on Sat Dec 16 08:28:56 GMT 2023
PRIMARY
DAILYMED
84RQ0XOM11
Created by admin on Sat Dec 16 08:28:56 GMT 2023 , Edited by admin on Sat Dec 16 08:28:56 GMT 2023
PRIMARY
SMS_ID
300000033938
Created by admin on Sat Dec 16 08:28:56 GMT 2023 , Edited by admin on Sat Dec 16 08:28:56 GMT 2023
PRIMARY
CAS
1449-61-2
Created by admin on Sat Dec 16 08:28:56 GMT 2023 , Edited by admin on Sat Dec 16 08:28:56 GMT 2023
PRIMARY
PUBCHEM
9798229
Created by admin on Sat Dec 16 08:28:56 GMT 2023 , Edited by admin on Sat Dec 16 08:28:56 GMT 2023
PRIMARY
EPA CompTox
DTXSID70932445
Created by admin on Sat Dec 16 08:28:56 GMT 2023 , Edited by admin on Sat Dec 16 08:28:56 GMT 2023
PRIMARY
NSC
134911
Created by admin on Sat Dec 16 08:28:56 GMT 2023 , Edited by admin on Sat Dec 16 08:28:56 GMT 2023
PRIMARY
Related Record Type Details
METABOLITE -> PARENT
Plasma concentrations 12 hours after the 3.beta.-acetyl-7-oxo-DHEA dose at 7 and 28 days on the 200 mg/d dose were 15.8 and 16.3 mcg/L respectively (n=16).
IN-VIVO
PLASMA
METABOLITE ACTIVE -> PRODRUG