ICI-164384

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C34H55NO3
Molecular Weight	525.8054
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCN(C)C(=O)CCCCCCCCCC[C@@H]1CC2=CC(O)=CC=C2[C@H]3CC[C@]4(C)[C@@H](O)CC[C@H]4[C@H]13

InChI

InChIKey=BVVFOLSZMQVDKV-KXQIQQEYSA-N

InChI=1S/C34H55NO3/c1-4-5-22-35(3)32(38)15-13-11-9-7-6-8-10-12-14-25-23-26-24-27(36)16-17-28(26)29-20-21-34(2)30(33(25)29)18-19-31(34)37/h16-17,24-25,29-31,33,36-37H,4-15,18-23H2,1-3H3/t25-,29-,30+,31+,33-,34+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C34H55NO3
Molecular Weight	525.8054
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Olfactomedin-4 regulation by estrogen in the human endometrium requires epidermal growth factor signaling.	2010-11	21048224
Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications.	2010-02-15	19913605
Downregulation of SIAH2, an ubiquitin E3 ligase, is associated with resistance to endocrine therapy in breast cancer.	2009-07	18629630
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006-11	16497524
Serum free BG-1 cell proliferation assay: a sensitive method for determining organochlorine pesticide estrogen receptor activation at the nanomolar range.	2006-04	16242299
Methyl mercury influences growth-related signaling in MCF-7 breast cancer cells.	2005-02	15712295
The unusual binding properties of the third distinct teleost estrogen receptor subtype ERbetaa are accompanied by highly conserved amino acid changes in the ligand binding domain.	2004-06	15001543
Transcriptional activation of heat shock protein 27 gene expression by 17beta-estradiol and modulation by antiestrogens and aryl hydrocarbon receptor agonists.	2001-02	11174852
Pure antiestrogens and breast cancer.	2001	11922402
Differential estrogen receptor binding of estrogenic substances: a species comparison.	2000-11-15	11162928
Estrogenic potential of certain pyrethroid compounds in the MCF-7 human breast carcinoma cell line.	1999-03	10064545
Influence of xenobiotics on rainbow trout liver estrogen receptor and vitellogenin gene expression.	1995-10	8800639
Effect of cadmium on estrogen receptor levels and estrogen-induced responses in human breast cancer cells.	1994-06-17	8207012
2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced thymic atrophy and lymphocyte stem cell alterations by mechanisms independent of the estrogen receptor.	1994-06-01	8010988

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:43:29 GMT 2025` Edited by `admin` on `Mon Mar 31 19:43:29 GMT 2025`
Record UNII	84LT43726C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ICI-164384

Common Name

English

ICI 164,384

Preferred Name

English

N-BUTYL-11-((17.BETA.)-3,17-DIHYDROXYESTRA-1,3,5(10)-TRIEN-7-YL)-N-METHYLUNDECANAMIDE

Systematic Name

English

ICI 164384

Common Name

English

UNDECANAMIDE, N-BUTYL-11-((17.BETA.)-3,17-DIHYDROXYESTRA-1,3,5(10)-TRIEN-7-YL)-N-METHYL-

Systematic Name

English

Code System Code Type Description

FDA UNII

84LT43726C