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Details

Stereochemistry ABSOLUTE
Molecular Formula C13H18Cl2N2O2.ClH
Molecular Weight 341.661
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SARCOLYSIN HYDROCHLORIDE, D-

SMILES

Cl.N[C@H](CC1=CC=C(C=C1)N(CCCl)CCCl)C(O)=O

InChI

InChIKey=OUUYBRCCFUEMLH-UTONKHPSSA-N
InChI=1S/C13H18Cl2N2O2.ClH/c14-5-7-17(8-6-15)11-3-1-10(2-4-11)9-12(16)13(18)19;/h1-4,12H,5-9,16H2,(H,18,19);1H/t12-;/m1./s1

HIDE SMILES / InChI
Molecular Formula C13H18Cl2N2O2
Molecular Weight 305.2
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 1 / 1
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

The D-isomer of melphalan, known as medphalan, is less active against certain animal tumors and the dose needed to produce effects on chromosomes is larger than that required with the L-isomer.

Originator

Approval Year

Unknown
139594
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Sat Dec 16 08:15:05 GMT 2023
Edited
by admin
on Sat Dec 16 08:15:05 GMT 2023
Record UNII
844HA6419R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SARCOLYSIN HYDROCHLORIDE, D-
Common Name English
D-PHENYLALANINE MUSTARD HYDROCHLORIDE
Common Name English
MEDPHALAN HYDROCHLORIDE
Common Name English
ALANINE, 3-(P-(BIS(2-CHLOROETHYL)AMINO)PHENYL)-, MONOHYDROCHLORIDE, D-
Systematic Name English
D-PHENYLALANINE, 4-(BIS(2-CHLOROETHYL)AMINO)-, MONOHYDROCHLORIDE
Systematic Name English
D-SARCOLYSINE HYDROCHLORIDE
Common Name English
Code System Code Type Description
FDA UNII
844HA6419R
Created by admin on Sat Dec 16 08:15:05 GMT 2023 , Edited by admin on Sat Dec 16 08:15:05 GMT 2023
PRIMARY
PUBCHEM
20188
Created by admin on Sat Dec 16 08:15:05 GMT 2023 , Edited by admin on Sat Dec 16 08:15:05 GMT 2023
PRIMARY
CAS
4213-32-5
Created by admin on Sat Dec 16 08:15:05 GMT 2023 , Edited by admin on Sat Dec 16 08:15:05 GMT 2023
PRIMARY
NIH
NCATS
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