| Stereochemistry | ABSOLUTE |
| Molecular Formula | C17H26N8O5 |
| Molecular Weight | 422.4389 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(CC[C@H](N)CC(=O)N[C@@H]1C=C[C@H](O[C@H]1C(O)=O)N2C=CC(N)=NC2=O)C(N)=N
InChI
InChIKey=CXNPLSGKWMLZPZ-GIFSMMMISA-N
InChI=1S/C17H26N8O5/c1-24(16(20)21)6-4-9(18)8-12(26)22-10-2-3-13(30-14(10)15(27)28)25-7-5-11(19)23-17(25)29/h2-3,5,7,9-10,13-14H,4,6,8,18H2,1H3,(H3,20,21)(H,22,26)(H,27,28)(H2,19,23,29)/t9-,10+,13-,14+/m0/s1
| Molecular Formula | C17H26N8O5 |
| Molecular Weight | 422.4389 |
| Charge | 0 |
| Count |
MOL RATIO
1 MOL RATIO (average) |
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Blasticidin S is a metabolite of Streptomyces griseochromogenes
and was formerly used in practice as a fungicide against
a phytopathogenic fungus, Pyricularia oryzae.
Blasticidin S inhibits protein synthesis of both prokaryotic and eukaryotic
organisms by interacting with their ribosomes. Blasticidin S, a protein synthesis inhibitor, inhibits aflatoxin production of Aspergillus flavus without affecting fungal growth. It has been demonstrated that blasticidin S also exhibits
antibacterial activity, toxicity to mammalians and tumor-inhibitory activity.