AMFLUTIZOLE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H7F3N2O2S
Molecular Weight	288.246
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of AMFLUTIZOLE

Structure Search

SMILES

NC1=C(SN=C1C2=CC(=CC=C2)C(F)(F)F)C(O)=O

InChI

InChIKey=KVMCEGAWQYTFKC-UHFFFAOYSA-N

InChI=1S/C11H7F3N2O2S/c12-11(13,14)6-3-1-2-5(4-6)8-7(15)9(10(17)18)19-16-8/h1-4H,15H2,(H,17,18)

HIDE SMILES / InChI

Molecular Formula	C11H7F3N2O2S
Molecular Weight	288.246
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/mesh/67046749 | https://www.ncbi.nlm.nih.gov/pubmed/3900392

AMFLUTIZOLE is a xanthine oxidase inhibitor used for the treatment of gout.

Approval Year

PubMed

PubMed

Title	Date	PubMed
Amflutizole, a xanthine oxidase inhibitor, inhibits free radical generation in the ischemic/reperfused rat cerebral cortex.	1994 Mar 14	8047280

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:17:44 GMT 2023` Edited by `admin` on `Fri Dec 15 15:17:44 GMT 2023`
Record UNII	83N680M457
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AMFLUTIZOLE

Official Name

English

5-ISOTHIAZOLECARBOXYLIC ACID, 4-AMINO-3-(3-(TRIFLUOROMETHYL)PHENYL)-

Common Name

English

LY-141894

Code

English

LY 141894

Code

English

AMFLUTIZOLE [USAN]

Common Name

English

amflutizole [INN]

Common Name

English

4-AMINO-3-(.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)-5-ISOTHIAZOLECARBOXYLIC ACID

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1637

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

Code System Code Type Description

INN

5421

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

PRIMARY

WIKIPEDIA

AMFLUTIZOLE

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

PRIMARY

ChEMBL

CHEMBL2106558

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

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NCI_THESAURUS

C91009

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

PRIMARY

CAS

82114-19-0

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

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FDA UNII

83N680M457

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

PRIMARY

PUBCHEM

54833

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

PRIMARY

EVMPD

SUB05420MIG

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

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MESH

C046749

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

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USAN

T-116

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

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EPA CompTox

DTXSID00868642

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

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SMS_ID

100000087218

Created by admin on Fri Dec 15 15:17:44 GMT 2023 , Edited by admin on Fri Dec 15 15:17:44 GMT 2023

PRIMARY

Related Record Type Details


					83N680M457

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