Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C11H21N3O5.2H2O |
| Molecular Weight | 311.3321 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.O.NCCCC[C@H](N)C(=O)N[C@@H](CCC(O)=O)C(O)=O
InChI
InChIKey=MINFJZILONFWCU-FOMWZSOGSA-N
InChI=1S/C11H21N3O5.2H2O/c12-6-2-1-3-7(13)10(17)14-8(11(18)19)4-5-9(15)16;;/h7-8H,1-6,12-13H2,(H,14,17)(H,15,16)(H,18,19);2*1H2/t7-,8-;;/m0../s1
| Molecular Formula | C11H21N3O5 |
| Molecular Weight | 275.3015 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | H2O |
| Molecular Weight | 18.0153 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| [Effect of vilon and epithalone on induction and growth of induced bladder neoplasms in rats]. | 2001 |
|
| Effects of peptides on generation of reactive oxygen species in subcellular fractions of Drosophila melanogaster. | 2001 Jul |
|
| Modulating and protective effects of thymic peptides in lymphoid tissue culture. | 2001 Jul-Aug |
|
| Effect of the dipeptide vilon on activity of digestive enzyme in rats of various ages. | 2001 Jun |
|
| Inhibitory effect of peptide vilon on the development of induced rat urinary bladder tumors in rats. | 2001 Jun |
|
| Immunohistochemical and morphometric analysis of effects of vilon and epithalon on functional morphology of radiosensitive organs. | 2001 Mar |
|
| [Characteristics of effect of ultralow doses of vilon in organotypic culture of spleens from rats of various ages]. | 2002 |
|
| [Effect of Epitalon and Vilon treatment on mammary carcinogenesis in transgenic erbB-2/NEU mice]. | 2002 |
|
| [Functional morphology of organotypic culture of spleens from rats of various ages exposed to vilon]. | 2002 |
|
| [The effect of vilon on the thymus and spleen in a radiation model of premature aging]. | 2002 |
|
| Effect of vilon and epithalon on activity of enzymes in epithelial and subepithelial layers in small intestine of old rats. | 2002 Dec |
|
| Epithalon inhibits tumor growth and expression of HER-2/neu oncogene in breast tumors in transgenic mice characterized by accelerated aging. | 2002 Feb |
|
| In vitro effect of short peptides on expression of interleukin-2 gene in splenocytes. | 2002 Jun |
|
| Studies of the effects of Vilon and Epithalon on gene expression in mouse heart using DNA-microarray technology. | 2002 Mar |
|
| Effects of short peptides on thymocyte blast transformation and signal transduction along the sphingomyelin pathway. | 2002 May |
|
| Effect of Vilon and Epithalon on glucose and glycine absorption in various regions of small intestine in aged rats. | 2002 May |
|
| [Effect of dipeptide vilon on emotional stress resistance in rats]. | 2002 Nov |
|
| Inhibitory effect of the peptide epitalon on the development of spontaneous mammary tumors in HER-2/neu transgenic mice. | 2002 Sep 1 |
|
| [Combined effect of vilon and cyclophosphane on tumor transplants and lymphoid tissue explants in mice and rats of various age]. | 2003 |
|
| [Reciprocal relation of proliferative activity in central and peripheral zones of splenic organ culture exposed to vilon in rats of various ages]. | 2003 |
|
| [The study of the role of the water medium in the mechanism of action of peptides in low and ultra low doses]. | 2003 May-Jun |
|
| [The study of peptide effect in the mechanisms of angiogenesis and forming of microenvironment of the tumors in old rats]. | 2004 |
|
| Bioregulator Vilon-induced reactivation of chromatin in cultured lymphocytes from old people. | 2004 |
|
| Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray. | 2004 Feb-Apr |
|
| Expression of argyrophilic proteins in the nucleolar organizer regions of human thymocytes and thymic epitheliocytes under conditions of coculturing with vilon and epithalon peptides. | 2004 Jun |
|
| [The effect of vilon (Lys-Glu) on 1.2-dimethylhydrazine-induced neoplasia]. | 2005 |
|
| [Application of peptide bioregulator in complex treatment of elderly cancer patients]. | 2005 |
|
| [Vilon effect on consequences of repeated radioactive and mercuric impact in small doses]. | 2005 |
|
| Effect of peptide Vilon on the content of transforming growth factor-beta and permeability of microvessels during experimental chronic renal failure. | 2005 Jan |
|
| [Effect of thymomimetic vilon on blood coagulation system and fibrinolisis in diabetes mellitus type 1 patients of different age]. | 2006 |
|
| [Effect of vilon on neuroendocrine status and sexual function of old male rats]. | 2006 |
|
| Interleukin-2 concentration in hypothalamic structures of rats receiving peptides during mild stress. | 2006 Apr |
|
| Anti-aging peptide bioregulators induce reactivation of chromatin. | 2006 Apr |
|
| [Effect of vilon on the immunity status and coagulation hemostasis in patients of different age with diabetes mellitus]. | 2007 |
|
| [Parallel analysis of c-Fos protein and interleukin-2 expression in hypothalamic cells under different influence]. | 2007 Feb |
|
| Comparative analysis of the expression of c-Fos and interleukin-2 proteins in hypothalamus cells during various treatments. | 2008 Mar |
|
| [The use of peptide bioregulators for cancer prevention: results of 35 years of research experience and perspectives]. | 2009 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 04:41:35 GMT 2023
by
admin
on
Sat Dec 16 04:41:35 GMT 2023
|
| Record UNII |
832IRM2G6W
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
DTXSID30241585
Created by
admin on Sat Dec 16 04:41:35 GMT 2023 , Edited by admin on Sat Dec 16 04:41:35 GMT 2023
|
PRIMARY | |||
|
94729-48-3
Created by
admin on Sat Dec 16 04:41:35 GMT 2023 , Edited by admin on Sat Dec 16 04:41:35 GMT 2023
|
PRIMARY | |||
|
71587354
Created by
admin on Sat Dec 16 04:41:35 GMT 2023 , Edited by admin on Sat Dec 16 04:41:35 GMT 2023
|
PRIMARY | |||
|
832IRM2G6W
Created by
admin on Sat Dec 16 04:41:35 GMT 2023 , Edited by admin on Sat Dec 16 04:41:35 GMT 2023
|
PRIMARY | |||
|
SUB25762
Created by
admin on Sat Dec 16 04:41:35 GMT 2023 , Edited by admin on Sat Dec 16 04:41:35 GMT 2023
|
PRIMARY | |||
|
100000089891
Created by
admin on Sat Dec 16 04:41:35 GMT 2023 , Edited by admin on Sat Dec 16 04:41:35 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ANHYDROUS->SOLVATE | |||
|
|
PARENT -> SALT/SOLVATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |