Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C18H11NO2 |
| Molecular Weight | 273.2854 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
[O-][N+](=O)C1=CC2=C(C=CC3=C2C=CC=C3)C4=CC=CC=C14
InChI
InChIKey=UAWLTQJFZUYROA-UHFFFAOYSA-N
InChI=1S/C18H11NO2/c20-19(21)18-11-17-13-6-2-1-5-12(13)9-10-15(17)14-7-3-4-8-16(14)18/h1-11H
| Molecular Formula | C18H11NO2 |
| Molecular Weight | 273.2854 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| A novel approach for a toxicity prediction model of environmental pollutants by using a quantitative structure-activity relationship method based on toxicogenomics. | 2011 |
|
| 1-Nitropyrene stabilizes the mRNA of cytochrome P450 1a1, a carcinogen-metabolizing enzyme, via the Akt pathway. | 2009-12 |
|
| Stereoselective metabolism of the environmental mammary carcinogen 6-nitrochrysene to trans-1,2-dihydroxy-1,2-dihydro-6-nitrochrysene by aroclor 1254-treated rat liver microsomes and their comparative mutation profiles in a laci mammary epithelial cell line. | 2009-12 |
|
| Biological Basis of Differential Susceptibility to Hepatocarcinogenesis among Mouse Strains. | 2009-03 |
|
| Comparative mutational profiles of the environmental mammary carcinogen, 6-nitrochrysene and its metabolites in a lacI mammary epithelial cell line. | 2007-11 |
|
| Effects of the environmental mammary carcinogen 6-nitrochrysene on p53 and p21(Cip1) protein expression and cell cycle regulation in MCF-7 and MCF-10A cells. | 2007-10-20 |
|
| Polycyclic aromatic hydrocarbons (PAHs), nitrated PAHs and oxygenated PAHs in ambient air of the Marseilles area (South of France): concentrations and sources. | 2007-10-01 |
|
| Analytical method for determination of dinitropyrenes using gas chromatography-high-resolution mass spectrometry. | 2007-07-20 |
|
| Singlet excited-state dynamics of nitropolycyclic aromatic hydrocarbons: direct measurements by femtosecond fluorescence up-conversion. | 2007-02-01 |
|
| Vibrational and surface-enhanced vibrational spectra of 6-nitrochrysene. | 2005-01-14 |
|
| Identification of 5-(deoxyguanosin-N2-yl)- 1,2-dihydroxy-1,2-dihydro-6-aminochrysene as the major DNA lesion in the mammary gland of rats treated with the environmental pollutant 6-nitrochrysene. | 2004-12 |
|
| Derivatised carbon powder electrodes: reagentless pH sensors. | 2004-07-08 |
|
| Mammary carcinogenesis and molecular analysis of in vivo cII gene mutations in the mammary tissue of female transgenic rats treated with the environmental pollutant 6-nitrochrysene. | 2004-04 |
|
| Nitroarenes (selected) 6-nitrochrysene. | 2004 |
|
| Improvement of an automatic HPLC system for nitropolycyclic aromatic hydrocarbons: removal of an interfering peak and increase in the number of analytes. | 2003-02 |
|
| Metabolism and DNA binding of the environmental pollutant 6-nitrochrysene in primary culture of human breast cells and in cultured MCF-10A, MCF-7 and MDA-MB-435s cell lines. | 2002-08-01 |
|
| Comparative tumorigenicity of the environmental pollutant 6-nitrochrysene and its metabolites in the rat mammary gland. | 2002-07 |
|
| Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences. | 2002-06 |
|
| Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer. | 2002-01 |
|
| Nitroarenes (selected). 6-Nitrochrysene. | 2002 |
|
| Characterization of a major aromatic DNA adduct detected in human breast tissues. | 2002 |
|
| Cytochrome P450 induction by nitrated polycyclic aromatic hydrocarbons, azaarenes, and binary mixtures in fish hepatoma cell line PLHC-1. | 2001-01 |
|
| Tumorigenicity of nitropolycyclic aromatic hydrocarbons in the neonatal B6C3F1 mouse bioassay and characterization of ras mutations in liver tumors from treated mice. | 1999-11-01 |
|
| Induction of cytochrome P450 1A in hamster liver and lung by 6-nitrochrysene. | 1998-06 |
|
| Tumorigenicity of nitrated derivatives of pyrene, benz[a]anthracene, chrysene and benzo[a]pyrene in the newborn mouse assay. | 1986-08 |
|
| Nitration of carcinogenic and non-carcinogenic polycyclic aromatic hydrocarbons results in products able to induce transformation of Syrian hamster cells. | 1983 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:34:08 GMT 2025
by
admin
on
Mon Mar 31 18:34:08 GMT 2025
|
| Record UNII |
82ZK83O33Y
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C45182
Created by
admin on Mon Mar 31 18:34:08 GMT 2025 , Edited by admin on Mon Mar 31 18:34:08 GMT 2025
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
407609
Created by
admin on Mon Mar 31 18:34:08 GMT 2025 , Edited by admin on Mon Mar 31 18:34:08 GMT 2025
|
PRIMARY | |||
|
82ZK83O33Y
Created by
admin on Mon Mar 31 18:34:08 GMT 2025 , Edited by admin on Mon Mar 31 18:34:08 GMT 2025
|
PRIMARY | |||
|
C29805
Created by
admin on Mon Mar 31 18:34:08 GMT 2025 , Edited by admin on Mon Mar 31 18:34:08 GMT 2025
|
PRIMARY | |||
|
24121
Created by
admin on Mon Mar 31 18:34:08 GMT 2025 , Edited by admin on Mon Mar 31 18:34:08 GMT 2025
|
PRIMARY | |||
|
DTXSID9075454
Created by
admin on Mon Mar 31 18:34:08 GMT 2025 , Edited by admin on Mon Mar 31 18:34:08 GMT 2025
|
PRIMARY | |||
|
7496-02-8
Created by
admin on Mon Mar 31 18:34:08 GMT 2025 , Edited by admin on Mon Mar 31 18:34:08 GMT 2025
|
PRIMARY | |||
|
7770
Created by
admin on Mon Mar 31 18:34:08 GMT 2025 , Edited by admin on Mon Mar 31 18:34:08 GMT 2025
|
PRIMARY |