SOCAZOLIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 18:54:07 GMT 2023` Edited by `admin` on `Sat Dec 16 18:54:07 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Record UNII	82P4S8Q3FB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SOCAZOLIMAB

Official Name

English

SH1E2

Code

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN PROGRAMMED DEATH-LIGAND 1) (HUMAN MONOCLONAL ZKAB001 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL ZKAB001 .LAMBDA.-CHAIN, DIMER

Common Name

English

SOCAZOLIMAB [USAN]

Common Name

English

IMMUNOGLOBULIN G1-LAMBDA2, ANTI-(HOMO SAPIENS CD274 (PROGRAMMED CELL DEATH 1 LIGAND 1, B7H1, B7-H1, PDL1, PD-L1, PDCD1L1, B7 HOMOLOG 1)), MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN (1-449) (VH (HOMO SAPIENS IGHV1-69*01 (98.0%)-(IGHD)-IGHJ6*01 (94.7%), CDR-I

Common Name

English

socazolimab [INN]

Common Name

English

ZKAB001

Code

English

ZKAB-001

Code

English

STI-A1014

Code

English

Code System Code Type Description

FDA UNII

82P4S8Q3FB

Created by admin on Sat Dec 16 18:54:07 GMT 2023 , Edited by admin on Sat Dec 16 18:54:07 GMT 2023

PRIMARY

CAS

2305043-30-3

Created by admin on Sat Dec 16 18:54:07 GMT 2023 , Edited by admin on Sat Dec 16 18:54:07 GMT 2023

PRIMARY

USAN

GH-198

Created by admin on Sat Dec 16 18:54:07 GMT 2023 , Edited by admin on Sat Dec 16 18:54:07 GMT 2023

PRIMARY

NCI_THESAURUS

C162504

Created by admin on Sat Dec 16 18:54:07 GMT 2023 , Edited by admin on Sat Dec 16 18:54:07 GMT 2023

PRIMARY

INN

11672

Created by admin on Sat Dec 16 18:54:07 GMT 2023 , Edited by admin on Sat Dec 16 18:54:07 GMT 2023

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_146	2_202
2_222	4_214
2_263	2_323
1_146	1_202
2_369	2_427
3_22	3_89
3_137	3_196
4_22	4_89
4_137	4_196
1_222	3_214
1_228	2_228
1_231	2_231
1_263	1_323
1_369	1_427

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_299
N	2_299

Related Record Type Details


					L4766ELH5T

PROGRAMMED CELL DEATH 1 LIGAND 1

TARGET->LIGAND

Amount:

Related Record Type Details


					82P4S8Q3FB

ACTIVE MOIETY

Comments:

Immunomodulator, antineoplastic

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL