U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 11:38:23 GMT 2023
Edited
by admin
on Sat Dec 16 11:38:23 GMT 2023
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
824XY5G677
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
C-C CHEMOKINE RECEPTOR-LIKE 2
Common Name English
CKRX
Common Name English
PUTATIVE MCP-1 CHEMOKINE RECEPTOR
Common Name English
CHEMOKINE RECEPTOR CCR11
Common Name English
CRAM
Common Name English
CCR6
Common Name English
CHEMOKINE RECEPTOR X
Common Name English
Code System Code Type Description
UNIPROT
O00421
Created by admin on Sat Dec 16 11:38:23 GMT 2023 , Edited by admin on Sat Dec 16 11:38:23 GMT 2023
PRIMARY
FDA UNII
824XY5G677
Created by admin on Sat Dec 16 11:38:23 GMT 2023 , Edited by admin on Sat Dec 16 11:38:23 GMT 2023
PRIMARY
From To
1_103 1_181
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_3
Related Record Type Details
INHIBITOR -> TARGET
Blocked in vitro CCL20-dependent human T cell chemotaxis. slow dissociation rate and consequent prolonged residence time of PF-07054894 on CCR6 is consistent with its insurmountable pattern of chemotaxis inhibition.
IC50
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL