Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C14H11N |
| Molecular Weight | 193.2438 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC1=CC2=CC3=CC=CC=C3C=C2C=C1
InChI
InChIKey=YCSBALJAGZKWFF-UHFFFAOYSA-N
InChI=1S/C14H11N/c15-14-6-5-12-7-10-3-1-2-4-11(10)8-13(12)9-14/h1-9H,15H2
| Molecular Formula | C14H11N |
| Molecular Weight | 193.2438 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Hepatic gene expression analysis of 2-aminoanthracene exposed Fisher-344 rats reveal patterns indicative of liver carcinoma and type 2 diabetes. | 2012 |
|
| Perfluorooctanoic acid (PFOA) but not perfluorooctane sulfonate (PFOS) showed DNA damage in comet assay on Paramecium caudatum. | 2010-12 |
|
| 2-Aminoanthracene, diethylstilboestrol and vinblastine tested in the in vitro mammalian cell micronucleus test at British American Tobacco UK in support of the OECD draft Test Guideline 487. | 2010-10-29 |
|
| 2-Aminoanthracene, 5-fluorouracil, colchicine, benzo[a]pyrene, cadmium chloride and cytosine arabinoside tested in the in vitro mammalian cell micronucleus test (MNvit) in Chinese hamster ovary (CHO) cells at Covance Laboratories, Harrogate UK in support of OECD draft Test Guideline 487. | 2010-10-29 |
|
| Cytosine arabinoside, vinblastine, 5-fluorouracil and 2-aminoanthracene testing in the in vitro micronucleus assay with L5178Y mouse lymphoma cells at Sanofi Aventis, with different cytotoxicity measurements, in support of the draft OECD Test Guideline on In Vitro Mammalian Cell Micronucleus Test. | 2010-10-29 |
|
| Cytosine arabinoside, vinblastine, diethylstilboestrol and 2-aminoanthracene tested in the in vitro human TK6 cell line micronucleus test (MNvit) at Institut Pasteur de Lille in support of OECD draft test guideline 487. | 2010-10-29 |
|
| Etoposide, cadmium chloride, benzo[a]pyrene, cyclophosphamide and colchicine tested in the in vitro mammalian cell micronucleus test (MNvit) in the presence and absence of cytokinesis block using L5178Y mouse lymphoma cells and 2-aminoanthracene tested in MNvit in the absence of cytokinesis block using TK6 cells at AstraZeneca UK, in support of OECD draft Test Guideline 487. | 2010-10-29 |
|
| Immunomodulatory effects of dietary exposure to selected polycyclic aromatic hydrocarbons in the bluegill (Lepomis macrochirus). | 2010-10-02 |
|
| Evaluation of extracts from Coccoloba mollis using the Salmonella/microsome system and in vivo tests. | 2010-07 |
|
| Spiro Tröger's base derivatives: another structural phoenix? | 2010-04-16 |
|
| Mutagenic, antimutagenic and antioxidant potency of leaf extracts from Nitraria retusa. | 2010-03-09 |
|
| Efficient and highly selective method for the synthesis of benzo(naphtho)quinoline derivatives catalyzed by iodine. | 2010-03-08 |
|
| Mutagenicity of new lead compounds to treat sickle cell disease symptoms in a Salmonella/microsome assay. | 2010-02-25 |
|
| Pharmacological and phytochemical study on a Sisymbrium officinale Scop. extract. | 2010-02-17 |
|
| Novel application of low pH-dependent fluorescent dyes to examine colitis. | 2010-01-15 |
|
| Mutagenic and antimutagenic activities of aqueous and methanol extracts of Euphorbia hirta. | 2009-12-10 |
|
| Identification of chemical compounds that induce HIF-1alpha activity. | 2009-11 |
|
| Antimutagenic activity of a secoisopimarane diterpenoid from Salvia cinnabarina M. Martens et Galeotti in the bacterial reverse mutation assay. | 2009-08 |
|
| Biological safety of LipoFullerene composed of squalane and fullerene-C60 upon mutagenesis, photocytotoxicity, and permeability into the human skin tissue. | 2009-06 |
|
| Mutagenicity of an aged gasworks soil during bioslurry treatment. | 2009-06 |
|
| Safety assessment of a proprietary preparation of a novel Probiotic, Bacillus coagulans, as a food ingredient. | 2009-06 |
|
| Embryotoxicity of retene in cotreatment with 2-aminoanthracene, a cytochrome P4501A inhibitor, in rainbow trout (Oncorhynchus mykiss). | 2009-06 |
|
| Biological safety of liposome-fullerene consisting of hydrogenated lecithin, glycine soja sterols, and fullerene-C60 upon photocytotoxicity and bacterial reverse mutagenicity. | 2009-04 |
|
| Design and microwave-assisted synthesis of naphtho[2,3-f]quinoline derivatives and their luminescent properties. | 2009-03-09 |
|
| Bioactivities of Piper aduncum L. and Piper obliquum Ruiz & Pavon (Piperaceae) essential oils from Eastern Ecuador. | 2009-01 |
|
| Screening of antimutagenicity via antioxidant activity in different extracts from the flowers of Phlomis crinita Cav. ssp mauritanica munby from the center of Tunisia. | 2009 |
|
| Cell protection induced by Acacia salicina extracts: inhibition of genotoxic damage and determination of its antioxidant capacity. | 2009 |
|
| Impairment of human CYP1A2-mediated xenobiotic metabolism by Antley-Bixler syndrome variants of cytochrome P450 oxidoreductase. | 2008-07-15 |
|
| In vitro study of mutagenic potential of Bidens pilosa Linné and Mikania glomerata Sprengel using the comet and micronucleus assays. | 2008-06-19 |
|
| Comparison of sensitivity of Escherichia coli WP2 tester strains with and without tolC outer membrane transport protein mutation in detecting chemical mutagens. | 2008-06-01 |
|
| Antimutagenic activity of a novel ascorbic derivative, disodium isostearyl 2-O-L-ascorbyl phosphate. | 2008-06 |
|
| Antimutagenic and mutagenic activities of some terpenes in the bacterial reverse mutation assay. | 2008-05-31 |
|
| Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. | 2008-04 |
|
| Anti-clastogenic effect of magnolol on benzo(a)pyrene-induced clastogenicity in mice. | 2008-02 |
|
| Intermediate frequency magnetic fields do not have mutagenic, co-mutagenic or gene conversion potentials in microbial genotoxicity tests. | 2008-01-08 |
|
| Suppression of mutagens-induced SOS response by phytoncide solution using Salmonella typhimurium TA1535/pSK1002 umu test. | 2008 |
|
| Initial in vitro screening approach to investigate the potential health and environmental hazards of Enviroxtrade mark - a nanoparticulate cerium oxide diesel fuel additive. | 2007-12-05 |
|
| Phytochemical profiling and phase II enzyme-inducing properties of Thunbergia laurifolia Lindl. (RC) extracts. | 2007-12-03 |
|
| The cda GenoTox assay: a new and sensitive method for detection of environmental genotoxins, including nitroarenes and aromatic amines. | 2007-07-28 |
|
| Antimutagenicity of Stevia pilosa and Stevia eupatoria evaluated with the Ames test. | 2007-06 |
|
| Anticancer effects of four varieties of muscadine grape. | 2007-03 |
|
| Effects of derivatization on solar-induced decomposition of polycyclic aromatic hydrocarbons in aqueous media. | 2007-02-15 |
|
| The stimulatory role of human cytochrome b5 in the bioactivation activities of human CYP1A2, 2A6 and 2E1: a new cell expression system to study cytochrome P450-mediated biotransformation (a corrigendum report on Duarte et al. (2005) Mutagenesis 20, 93-100). | 2007-01 |
|
| Antimutagenic, antioxidant and antimicrobial properties of Maytenus krukovii bark. | 2006-12 |
|
| Mutagenicity of cytochrome P450 2E1 substrates in the Ames test with the metabolic competent S. typhimurium strain YG7108pin3ERb5. | 2006-11-10 |
|
| In-vitro mutagenic potential and effect on permeability of co-administered drugs across Caco-2 cell monolayers of Rubus idaeus and its fortified fractions. | 2006-11 |
|
| In vitro anti-mutagenic effect of magnolol against direct and indirect mutagens. | 2006-10-10 |
|
| Deoxyribonucleic acid (DNA) biosensors for environmental risk assessment and drug studies. | 2006-07-28 |
|
| Genotoxic potency in Drosophila melanogaster of selected aromatic amines and polycyclic aromatic hydrocarbons as assayed in the DNA repair test. | 1993-12 |
|
| Human liver microsomal cytochrome P-450 enzymes involved in the bioactivation of procarcinogens detected by umu gene response in Salmonella typhimurium TA 1535/pSK1002. | 1989-06-15 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:49:00 GMT 2025
by
admin
on
Mon Mar 31 18:49:00 GMT 2025
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| Record UNII |
8240818JGU
|
| Record Status |
Validated (UNII)
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| Record Version |
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613-13-8
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11937
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8240818JGU
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DTXSID2024458
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210-330-9
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C006593
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34260
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400535
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4041
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