Renvistobart

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National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 19:52:57 GMT 2025` Edited by `admin` on `Tue Apr 01 19:52:57 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	81J55YFQ16
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BMS-986207

Preferred Name

English

Renvistobart

Official Name

English

Immunoglobulin G1 [247-alanine,248-glutamic acid,250-alanine,343-serine,344-serine,de-C-terminal-lysine], anti-(human T cell immunoreceptor with Ig and ITIM domains) (human monoclonal BMS-986207 ?1-chain), disulfide with human monoclonal BMS-986207 ?-cha

Common Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens TIGIT (T cell immunoreceptor with Ig domain and ITIM, V-set Ig member 9, VSIG9, V-set and transmembrane member 3, VSTM3)], Homo sapiens monoclonal antibody (gamma1 heavy chain Homo sapiens (1-459) [VH (Homo sap

Common Name

English

ANTI-TIGIT MONOCLONAL ANTIBODY BMS-986207

Common Name

English

BMS986207

Code

English

Renvistobart [WHO-DD]

Common Name

English

renvistobart [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C129822

Created by admin on Tue Apr 01 19:52:57 GMT 2025 , Edited by admin on Tue Apr 01 19:52:57 GMT 2025

NCI_THESAURUS

C134787

Created by admin on Tue Apr 01 19:52:57 GMT 2025 , Edited by admin on Tue Apr 01 19:52:57 GMT 2025

Code System Code Type Description

INN

12465

Created by admin on Tue Apr 01 19:52:57 GMT 2025 , Edited by admin on Tue Apr 01 19:52:57 GMT 2025

PRIMARY

CAS

2725062-35-9

Created by admin on Tue Apr 01 19:52:57 GMT 2025 , Edited by admin on Tue Apr 01 19:52:57 GMT 2025

PRIMARY

FDA UNII

81J55YFQ16

Created by admin on Tue Apr 01 19:52:57 GMT 2025 , Edited by admin on Tue Apr 01 19:52:57 GMT 2025

PRIMARY

SMS_ID

300000024354

Created by admin on Tue Apr 01 19:52:57 GMT 2025 , Edited by admin on Tue Apr 01 19:52:57 GMT 2025

PRIMARY

NCI_THESAURUS

C131907

Created by admin on Tue Apr 01 19:52:57 GMT 2025 , Edited by admin on Tue Apr 01 19:52:57 GMT 2025

PRIMARY

From	To
1_22	1_97
1_157	1_213
1_233	3_216
1_239	2_239
1_242	2_242
1_274	1_334
1_380	1_438
2_22	2_97
2_157	2_213
2_233	4_216
2_274	2_334
2_380	2_438
3_23	3_88
3_136	3_196
4_23	4_88
4_136	4_196

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_310
N	2_310

Related Record Type Details


					3GY58DVB2F

T-CELL IMMUNORECEPTOR WITH IG AND ITIM DOMAINS

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					81J55YFQ16

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_1] [2_1]		Q		PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL