TRIMELLITIC ANHYDRIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H4O5
Molecular Weight	192.1251
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)C1=CC2=C(C=C1)C(=O)OC2=O

InChI

InChIKey=SRPWOOOHEPICQU-UHFFFAOYSA-N

InChI=1S/C9H4O5/c10-7(11)4-1-2-5-6(3-4)9(13)14-8(5)12/h1-3H,(H,10,11)

HIDE SMILES / InChI

Molecular Formula	C9H4O5
Molecular Weight	192.1251
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Inhalation exposure of mice to trimellitic anhydride induces both IgG and IgE anti-hapten antibody.	1991	1917113
Immunologic effector mechanisms in animal models of occupational asthma.	2004 Jan	18958638
Arginase activity differs with allergen in the effector phase of ovalbumin- versus trimellitic anhydride-induced asthma.	2005 Dec	16141432
Formation of molecular bundles from self-assembly of symmetrical poly(oxyalkylene)-diamido acids.	2005 Jul 21	16852689
Genistein enhancement of respiratory allergen trimellitic anhydride-induced IgE production by adult B6C3F1 mice following in utero and postnatal exposure.	2005 Oct	16049267
Roles of TNF-alpha and IgE in the late phase of contact hypersensitivity induced by trimellitic anhydride.	2005 Oct 31	16264265
Airway responses in Brown Norway rats following inhalation sensitization and challenge with trimellitic anhydride.	2006 Dec	16982671
Alveolar macrophages have a dual role in a rat model for trimellitic anhydride-induced occupational asthma.	2006 Feb 15	15992840
Satratoxin G from the black mold Stachybotrys chartarum evokes olfactory sensory neuron loss and inflammation in the murine nose and brain.	2006 Jul	16835065
Topical application versus intranasal instillation: a qualitative comparison of the effect of the route of sensitization on trimellitic anhydride-induced allergic rhinitis in A/J mice.	2006 Jul	16611626
Trimellitic anhydride-conjugated serum albumin activates rat alveolar macrophages in vitro.	2006 Jun 23	16796737
Validation of a mouse model of chemical-induced asthma using trimellitic anhydride, a respiratory sensitizer, and dinitrochlorobenzene, a dermal sensitizer.	2006 May	16675337
Allergic contact dermatitis to copolymers in cosmetics--case report and review of the literature.	2006 Nov	17026690
Alveolar macrophages suppress non-specific inflammation caused by inhalation challenge with trimellitic anhydride conjugated to albumin.	2006 Sep	16485118
Assessment of airway sensitization potential of inhaled trimellitic anhydride by monitoring the elicitation phase in a mouse model.	2007 Apr	18958718
Metal complexes of crosslinked chitosans Part II. An investigation of their hydrolysis to chitooligosaccharides using chitosanase.	2007 Dec 1	17673286
Maternal allergic contact dermatitis causes increased asthma risk in offspring.	2007 Jul 27	17662138
Skin exposure to isocyanates: reasons for concern.	2007 Mar	17431479
A rare nail polish allergen: phthalic anhydride, trimellitic anhydride and glycols copolymer.	2007 Mar	17295698
Effects of a diphtheria-tetanus-acellular pertussis vaccine on immune responses in murine local lymph node and lung allergy models.	2007 Mar	17202304
Synthesis of new silane coupling agents with a trimellitic anhydride group and application as primers for ceramics and alloys.	2007 Nov	18203484
Comparative studies of lymph node cell subpopulations and cytokine expression in murine model for testing the potentials of chemicals to induce respiratory sensitization.	2008	19042193
Photostable, amino reactive and water-soluble fluorescent labels based on sulfonated rhodamine with a rigidized xanthene fragment.	2008	18058955
Preexposure to amorphous silica particles attenuates but also enhances allergic reactions in trimellitic anhydride-sensitized brown Norway rats.	2008 Aug	18668410
Arginase and pulmonary diseases.	2008 Aug	18437360
Molecular characterization of trimellitic anhydride-induced respiratory allergy in Brown Norway rats.	2008 Dec	19126793
The respiratory local lymph node assay as a tool to study respiratory sensitizers.	2008 Dec	18815142
Environment friendly crosslinked chitosan as a matrix for selective adsorption and purification of lipase of Aspergillus niger.	2008 Dec	18789352
Ex vivo lung function measurements in precision-cut lung slices (PCLS) from chemical allergen-sensitized mice represent a suitable alternative to in vivo studies.	2008 Dec	18775882
CCR4 and CCR10 ligands play additive roles in mouse contact hypersensitivity.	2008 Jan	18095942
Dendritic cells from control but not atopic donors respond to contact and respiratory sensitizer treatment in vitro with differential cytokine production and altered stimulatory capacity.	2008 Jul	18498417
Detection of low-level environmental chemical allergy by a long-term sensitization method.	2008 Jul 30	18571882
Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THp-1 cells.	2008 Mar	18494145
Synthesis of 5- and 6-carboxy-X-rhodamines.	2008 Nov 6	18837556
Use of long term dermal sensitization followed by intratracheal challenge method to identify low-dose chemical-induced respiratory allergic responses in mice.	2008 Oct 1	18708131
Cytokine profiling of chemical allergens in mice: measurement of message versus protein.	2008 Oct 30	18708116
Cytokine profiling of chemical allergens in mice: impact of mitogen on selectivity of response.	2009 Apr	19021154
Chronic mouse model of TMA-induced contact hypersensitivity.	2009 Apr	18830270
Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens.	2009 Aug	19397996
Practical synthesis of isomerically pure 5- and 6-carboxytetramethylrhodamines, useful dyes for DNA probes.	2009 Aug 19	19606815
Evaluation of a toxicogenomic approach to the local lymph node assay (LLNA).	2009 Feb	19042947
Gene profiles of a human alveolar epithelial cell line after in vitro exposure to respiratory (non-)sensitizing chemicals: identification of discriminating genetic markers and pathway analysis.	2009 Feb 25	19110044
Gene profiles of a human bronchial epithelial cell line after in vitro exposure to respiratory (non-)sensitizing chemicals: identification of discriminating genetic markers and pathway analysis.	2009 Jan 31	19041681
Contact and respiratory sensitizers can be identified by cytokine profiles following inhalation exposure.	2009 Jul 10	19422874
Investigation of the chemical-induced selective type II (T(H)2) allergic response in mice: effect of the length of the sensitizing phase.	2009 Jun	19589094
EAACI position paper on occupational rhinitis.	2009 Mar 3	19257881
Changes in asthma-like responses after extended removal from exposure to trimellitic anhydride in the Brown Norway rat model.	2009 Nov	19549025
Gene profiles of THP-1 macrophages after in vitro exposure to respiratory (non-)sensitizing chemicals: identification of discriminating genetic markers and pathway analysis.	2009 Sep	19527780
Smad3 regulates dermal cytokine and chemokine expression and specific antibody production in murine responses to a respiratory chemical sensitizer.	2010	19752570
Rosin-derived imide-diacids as epoxy curing agents for enhanced performance.	2010 Apr	19963371

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:51:22 GMT 2023` Edited by `admin` on `Fri Dec 15 18:51:22 GMT 2023`
Record UNII	80T61EUU7H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRIMELLITIC ANHYDRIDE

Official Name

English

TRIMELLITIC ANHYDRIDE [MI]

Common Name

English

1,3-DIHYDRO-1,3-DIOXO-5-ISOBENZOFURANCARBOXYLIC ACID

Systematic Name

English

TRIMELLITIC ANHYDRIDE [INCI]

Common Name

English

NSC-60252

Code

English

TRIMELLITIC ACID 1,2-ANHYDRIDE

Common Name

English

TRIMELLITIC ANHYDRIDE [HSDB]

Common Name

English

Classification Tree Code System Code

Food Contact Sustance Notif, (FCN No.)

FCN NO. 729