TRIMELLITIC ANHYDRIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H4O5
Molecular Weight	192.1251
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC(=O)C1=CC=C2C(=O)OC(=O)C2=C1

InChI

InChIKey=SRPWOOOHEPICQU-UHFFFAOYSA-N

InChI=1S/C9H4O5/c10-7(11)4-1-2-5-6(3-4)9(13)14-8(5)12/h1-3H,(H,10,11)

HIDE SMILES / InChI

Molecular Formula	C9H4O5
Molecular Weight	192.1251
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Rosin-derived imide-diacids as epoxy curing agents for enhanced performance.	2010-04	19963371
Smad3 regulates dermal cytokine and chemokine expression and specific antibody production in murine responses to a respiratory chemical sensitizer.	2010	19752570
Changes in asthma-like responses after extended removal from exposure to trimellitic anhydride in the Brown Norway rat model.	2009-11	19549025
Gene profiles of THP-1 macrophages after in vitro exposure to respiratory (non-)sensitizing chemicals: identification of discriminating genetic markers and pathway analysis.	2009-09	19527780
Practical synthesis of isomerically pure 5- and 6-carboxytetramethylrhodamines, useful dyes for DNA probes.	2009-08-19	19606815
Use of IL-18 production in a human keratinocyte cell line to discriminate contact sensitizers from irritants and low molecular weight respiratory allergens.	2009-08	19397996
Contact and respiratory sensitizers can be identified by cytokine profiles following inhalation exposure.	2009-07-10	19422874
Investigation of the chemical-induced selective type II (T(H)2) allergic response in mice: effect of the length of the sensitizing phase.	2009-06	19589094
Cytokine profiling of chemical allergens in mice: impact of mitogen on selectivity of response.	2009-04	19021154
Chronic mouse model of TMA-induced contact hypersensitivity.	2009-04	18830270
EAACI position paper on occupational rhinitis.	2009-03-03	19257881
Gene profiles of a human alveolar epithelial cell line after in vitro exposure to respiratory (non-)sensitizing chemicals: identification of discriminating genetic markers and pathway analysis.	2009-02-25	19110044
Evaluation of a toxicogenomic approach to the local lymph node assay (LLNA).	2009-02	19042947
Gene profiles of a human bronchial epithelial cell line after in vitro exposure to respiratory (non-)sensitizing chemicals: identification of discriminating genetic markers and pathway analysis.	2009-01-31	19041681
Molecular characterization of trimellitic anhydride-induced respiratory allergy in Brown Norway rats.	2008-12	19126793
The respiratory local lymph node assay as a tool to study respiratory sensitizers.	2008-12	18815142
Environment friendly crosslinked chitosan as a matrix for selective adsorption and purification of lipase of Aspergillus niger.	2008-12	18789352
Ex vivo lung function measurements in precision-cut lung slices (PCLS) from chemical allergen-sensitized mice represent a suitable alternative to in vivo studies.	2008-12	18775882
Synthesis of 5- and 6-carboxy-X-rhodamines.	2008-11-06	18837556
Cytokine profiling of chemical allergens in mice: measurement of message versus protein.	2008-10-30	18708116
Use of long term dermal sensitization followed by intratracheal challenge method to identify low-dose chemical-induced respiratory allergic responses in mice.	2008-10-01	18708131
Preexposure to amorphous silica particles attenuates but also enhances allergic reactions in trimellitic anhydride-sensitized brown Norway rats.	2008-08	18668410
Arginase and pulmonary diseases.	2008-08	18437360
Detection of low-level environmental chemical allergy by a long-term sensitization method.	2008-07-30	18571882
Dendritic cells from control but not atopic donors respond to contact and respiratory sensitizer treatment in vitro with differential cytokine production and altered stimulatory capacity.	2008-07	18498417
Role of p38 MAPK in the selective release of IL-8 induced by chemical allergen in naive THp-1 cells.	2008-03	18494145
CCR4 and CCR10 ligands play additive roles in mouse contact hypersensitivity.	2008-01	18095942
Comparative studies of lymph node cell subpopulations and cytokine expression in murine model for testing the potentials of chemicals to induce respiratory sensitization.	2008	19042193
Photostable, amino reactive and water-soluble fluorescent labels based on sulfonated rhodamine with a rigidized xanthene fragment.	2008	18058955
Metal complexes of crosslinked chitosans Part II. An investigation of their hydrolysis to chitooligosaccharides using chitosanase.	2007-12-01	17673286
Synthesis of new silane coupling agents with a trimellitic anhydride group and application as primers for ceramics and alloys.	2007-11	18203484
Maternal allergic contact dermatitis causes increased asthma risk in offspring.	2007-07-27	17662138
Assessment of airway sensitization potential of inhaled trimellitic anhydride by monitoring the elicitation phase in a mouse model.	2007-04	18958718
Skin exposure to isocyanates: reasons for concern.	2007-03	17431479
A rare nail polish allergen: phthalic anhydride, trimellitic anhydride and glycols copolymer.	2007-03	17295698
Effects of a diphtheria-tetanus-acellular pertussis vaccine on immune responses in murine local lymph node and lung allergy models.	2007-03	17202304
Airway responses in Brown Norway rats following inhalation sensitization and challenge with trimellitic anhydride.	2006-12	16982671
Allergic contact dermatitis to copolymers in cosmetics--case report and review of the literature.	2006-11	17026690
Alveolar macrophages suppress non-specific inflammation caused by inhalation challenge with trimellitic anhydride conjugated to albumin.	2006-09	16485118
Satratoxin G from the black mold Stachybotrys chartarum evokes olfactory sensory neuron loss and inflammation in the murine nose and brain.	2006-07	16835065
Topical application versus intranasal instillation: a qualitative comparison of the effect of the route of sensitization on trimellitic anhydride-induced allergic rhinitis in A/J mice.	2006-07	16611626
Trimellitic anhydride-conjugated serum albumin activates rat alveolar macrophages in vitro.	2006-06-23	16796737
Validation of a mouse model of chemical-induced asthma using trimellitic anhydride, a respiratory sensitizer, and dinitrochlorobenzene, a dermal sensitizer.	2006-05	16675337
Alveolar macrophages have a dual role in a rat model for trimellitic anhydride-induced occupational asthma.	2006-02-15	15992840
Arginase activity differs with allergen in the effector phase of ovalbumin- versus trimellitic anhydride-induced asthma.	2005-12	16141432
Roles of TNF-alpha and IgE in the late phase of contact hypersensitivity induced by trimellitic anhydride.	2005-10-31	16264265
Genistein enhancement of respiratory allergen trimellitic anhydride-induced IgE production by adult B6C3F1 mice following in utero and postnatal exposure.	2005-10	16049267
Formation of molecular bundles from self-assembly of symmetrical poly(oxyalkylene)-diamido acids.	2005-07-21	16852689
Immunologic effector mechanisms in animal models of occupational asthma.	2004-01	18958638
Inhalation exposure of mice to trimellitic anhydride induces both IgG and IgE anti-hapten antibody.	1991	1917113

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:22:46 GMT 2025` Edited by `admin` on `Mon Mar 31 19:22:46 GMT 2025`
Record UNII	80T61EUU7H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRIMELLITIC ANHYDRIDE

Official Name

English

NSC-60252

Preferred Name

English

TRIMELLITIC ANHYDRIDE [MI]

Common Name

English

1,3-DIHYDRO-1,3-DIOXO-5-ISOBENZOFURANCARBOXYLIC ACID

Systematic Name

English

TRIMELLITIC ACID 1,2-ANHYDRIDE

Common Name

English

TRIMELLITIC ANHYDRIDE [HSDB]

Common Name

English

Classification Tree Code System Code

Food Contact Sustance Notif, (FCN No.)

FCN NO. 729