PERFLUOROOCTANESULFONAMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H2F17NO2S
Molecular Weight	499.145
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

InChI

InChIKey=RRRXPPIDPYTNJG-UHFFFAOYSA-N

InChI=1S/C8H2F17NO2S/c9-1(10,3(13,14)5(17,18)7(21,22)23)2(11,12)4(15,16)6(19,20)8(24,25)29(26,27)28/h(H2,26,27,28)

HIDE SMILES / InChI

Molecular Formula	C8H2F17NO2S
Molecular Weight	499.145
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Perfluorooctane sulfonamide-mediated modulation of hepatocellular lipid homeostasis and oxidative stress responses in Atlantic salmon hepatocytes.	2012-06-18	22594583
Levels and trends of poly- and perfluorinated compounds in the arctic environment.	2010-07-01	20493516
Temporal trends of perfluorinated surfactants in Swedish peregrine falcon eggs (Falco peregrinus), 1974-2007.	2010-06-01	20446727
Effects of sorption on the rejection of trace organic contaminants during nanofiltration.	2010-04-01	20218539
Distribution of polyfluoroalkyl compounds in water, suspended particulate matter and sediment from Tokyo Bay, Japan.	2010-04	20181376
Exploratory assessment of perfluorinated compounds and human thyroid function.	2010-02-09	19419669
Distribution of perfluoroalkyl compounds in seawater from northern Europe, Atlantic Ocean, and Southern Ocean.	2010-02	20015534
Oxidative stress from diverse developmental neurotoxicants: antioxidants protect against lipid peroxidation without preventing cell loss.	2009-10-27	20004241
Subacute exposure to N-ethyl perfluorooctanesulfonamidoethanol results in the formation of perfluorooctanesulfonate and alters superoxide dismutase activity in female rats.	2009-10	19544052
Partitioning behavior of per- and polyfluoroalkyl compounds between pore water and sediment in two sediment cores from Tokyo Bay, Japan.	2009-09-15	19806729
An analytical method for the determination of perfluorinated compounds in whole blood using acetonitrile and solid phase extraction methods.	2009-06-19	19439311
Polyfluoroalkyl chemicals in pooled blood serum from infants, children, and adults in Australia.	2009-06-01	19569351
Do perfluoroalkyl compounds impair human semen quality?	2009-06	19590684
Temporal trends of polyfluoroalkyl compounds in harbor seals (Phoca vitulina) from the German Bight, 1999-2008.	2009-06	19394671
Indirect photolysis of perfluorochemicals: hydroxyl radical-initiated oxidation of N-ethyl perfluorooctane sulfonamido acetate (N-EtFOSAA) and other perfluoroalkanesulfonamides.	2009-05-15	19544870
Longitudinal and latitudinal distribution of perfluoroalkyl compounds in the surface water of the Atlantic Ocean.	2009-05-01	19534123
Correlations between prenatal exposure to perfluorinated chemicals and reduced fetal growth.	2009-04	19440508
Temporal trends (1992-2007) of perfluorinated chemicals in Northern Sea Otters (Enhydra lutris kenyoni) from South-Central Alaska.	2009-04	18839236
Analysis of fluorotelomer alcohols and perfluorinated sulfonamides in biotic samples by liquid chromatography-atmospheric pressure photoionization mass spectrometry.	2008-12-26	19010474
Perfluorooctane sulfonate (PFOS) and other fluorochemicals in fish blood collected near the outfall of wastewater treatment plant (WWTP) in Beijing.	2008-12	18439735
Potential effects of perfluorinated compounds in common cormorants from Lake Biwa, Japan: an implication from the hepatic gene expression profiles by microarray.	2008-11	18611081
Time trends and transplacental transfer of perfluorinated compounds in melon-headed whales stranded along the Japanese coast in 1982, 2001/2002, and 2006.	2008-10-01	18939537
Concentrations and patterns of perfluoroalkyl acids in Georgia, USA surface waters near and distant to a major use source.	2008-10	18419175
Occurrence and sources of perfluorinated surfactants in rivers in Japan.	2008-09-01	18800531
Cooking decreases observed perfluorinated compound concentrations in fish.	2008-08-27	18620413
Tissue distribution of perfluorinated surfactants in common guillemot (Uria aalge) from the Baltic Sea.	2008-08-15	18767639
Spatial trends of polyfluorinated compounds in guillemot (Uria aalge) eggs from North-Western Europe.	2008-08	18573516
Use of newborn screening program blood spots for exposure assessment: declining levels of perluorinated compounds in New York State infants.	2008-07-15	18754394
Nanofiltration for trace organic contaminant removal: structure, solution, and membrane fouling effects on the rejection of perfluorochemicals.	2008-07-15	18754383
Temporal trends of perfluoroalkyl compounds with isomer analysis in lake trout from Lake Ontario (1979-2004).	2008-07-01	18677999
Developmental neurotoxicity of perfluorinated chemicals modeled in vitro.	2008-06	18560525
Multiple evaluations of the removal of pollutants in road runoff by soil infiltration.	2008-05	18328527
Aerobic biotransformation and fate of N-ethyl perfluorooctane sulfonamidoethanol (N-EtFOSE) in activated sludge.	2008-04-15	18497137
Optimized method avoiding solvent-induced response enhancement in the analysis of volatile and semi-volatile polyfluorinated alkylated compounds using gas chromatography-mass spectrometry.	2008-01-18	18082170
[Perfluorinated compounds in potable water].	2008	19143425
Emissions of perfluorinated alkylated substances (PFAS) from point sources--identification of relevant branches.	2008	18653937
Exposure of an adult population to perfluorinated substances using duplicate diet portions and biomonitoring data.	2007-11-15	18075110
Polyfluoroalkyl chemicals in the U.S. population: data from the National Health and Nutrition Examination Survey (NHANES) 2003-2004 and comparisons with NHANES 1999-2000.	2007-11	18007991
Theoretical studies of the conformations and 19F NMR spectra of linear and a branched perfluorooctanesulfonamide (PFOSAmide).	2007-10	17640706
Simultaneous characterization of perfluoroalkyl carboxylate, sulfonate, and sulfonamide isomers by liquid chromatography-tandem mass spectrometry.	2007-09-01	17665875
Perfluorinated chemicals in blood of residents in Catalonia (Spain) in relation to age and gender: a pilot study.	2007-07	17289145
Perfluoroalkyl contaminants in the Canadian Arctic: evidence of atmospheric transport and local contamination.	2007-05-15	17547174
Perfluoroalkyl acids: what is the evidence telling us?	2007-05	17520044
Serum concentrations of 11 polyfluoroalkyl compounds in the u.s. population: data from the national health and nutrition examination survey (NHANES).	2007-04-01	17438769
Exposure of perfluorinated chemicals through lactation: levels of matched human milk and serum and a temporal trend, 1996-2004, in Sweden.	2007-02	17384769
Rapid response of Arctic ringed seals to changes in perfluoroalkyl production.	2007-01-01	17265925
Mass spectral studies of native and mass-labeled perfluorooctanesulfonamides.	2007	17295423
The applicability of biomonitoring data for perfluorooctanesulfonate to the environmental public health continuum.	2006-11	17107867
Concentrations of perfluorooctanesulfonamides in Canadian total diet study composite food samples collected between 1992 and 2004.	2006-10-18	17032055
[Levels of selected organochlorine insecticides, polychlorinated biphenyls, phthalates and perfluorinated aliphatic substances in blood--Polish WWF study].	2006	17044303

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:11:16 GMT 2025` Edited by `admin` on `Mon Mar 31 21:11:16 GMT 2025`
Record UNII	80AM718FML
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PERFLUOROOCTANESULFONAMIDE

Systematic Name

English

PFOSA

Preferred Name

English

Code System Code Type Description

MESH

C063900