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Details

Stereochemistry ACHIRAL
Molecular Formula C12H5Cl5
Molecular Weight 326.433
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 2,2',4,5,5'-PENTACHLOROBIPHENYL

SMILES

ClC1=CC(=C(Cl)C=C1)C2=C(Cl)C=C(Cl)C(Cl)=C2

InChI

InChIKey=LAHWLEDBADHJGA-UHFFFAOYSA-N
InChI=1S/C12H5Cl5/c13-6-1-2-9(14)7(3-6)8-4-11(16)12(17)5-10(8)15/h1-5H

HIDE SMILES / InChI

Molecular Formula C12H5Cl5
Molecular Weight 326.433
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Ortho-substituted polychlorinated biphenyl (PCB) congeners (95 or 101) decrease pituitary response to thyrotropin releasing hormone.
2003 Sep 30
An unrecognized source of PCB contamination in schools and other buildings.
2004 Jul
Retention indexes for temperature-programmed gas chromatography of polychlorinated biphenyls.
2004 Sep 15
Apoptosis in bovine cumulus-oocyte complexes after exposure to polychlorinated biphenyl mixtures during in vitro maturation.
2005 Dec
Lineage-specific effects of polychlorinated biphenyls (PCB) on gene expression in the rabbit blastocyst.
2005 May-Jun
Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls.
2006 Dec
Bioaccumulation of 14C-PCB 101 and 14C-PBDE 99 in the marine planktonic copepod Calanus finmarchicus under different food regimes.
2007 Feb
Pesticide contamination profiles of water, sediment and aquatic organisms in the effluent of Gaobeidian wastewater treatment plant.
2008 Jul
An Assessment of Mutagenic Effect of 3, 3', 4, 4', 5 Pentachlorobiphenyl (PCB126) in Muta Mouse Fetuses.
2009 Apr
Transactivation potencies of Baikal seal constitutive active/androstane receptor by persistent organic pollutants and brominated flame retardants.
2009 Aug 15
Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells.
2009 Dec 10
Cell death mechanisms in GT1-7 GnRH cells exposed to polychlorinated biphenyls PCB74, PCB118, and PCB153.
2009 Jun 1
Degradation of pentachlorobiphenyl by a sequential treatment using Pd coated iron and an aerobic bacterium (H1).
2009 Sep
Determination of lead, cadmium, and persistent organic pollutants in wild and orchard-farm-grown fruit in northeastern Poland.
2010
Non-dioxin-like PCBs interact with benzo[a]pyrene-induced p53-responses and inhibit apoptosis.
2010 Dec 1
Evaluation of an hPXR reporter gene assay for the detection of aquatic emerging pollutants: screening of chemicals and application to water samples.
2010 Jan
Effects of non-dioxin-like polychlorinated biphenyl congeners (PCB 101, PCB 153 and PCB 180) alone or mixed on J774A.1 macrophage cell line: modification of apoptotic pathway.
2011 Apr 10
Genotoxic effects of polychlorinated biphenyls (PCB 153, 138, 101, 118) in a fish cell line (RTG-2).
2011 Aug
In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans.
2011 May
Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO₂-PCBs.
2011 Oct 10
Neurodevelopmental and behavioral toxicity via lactational exposure to the sum of six indicator non-dioxin-like-polychlorinated biphenyls (∑6 NDL-PCBs) in mice.
2012 Sep 4
Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently.
2015 Apr 1
Non-dioxin-like polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) induce chondrocyte cell death through multiple pathways.
2015 Apr 2
Detection and measurement of the agonistic activities of PCBs and mono-hydroxylated PCBs to the constitutive androstane receptor using a recombinant yeast assay.
2015 Oct
Polychlorinated Biphenyls (PCB 101, 153, and 180) Impair Murine Macrophage Responsiveness to Lipopolysaccharide: Involvement of NF-κB Pathway.
2015 Sep
Substance Class Chemical
Created
by admin
on Sat Dec 16 03:10:19 GMT 2023
Edited
by admin
on Sat Dec 16 03:10:19 GMT 2023
Record UNII
803YVI5BNP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
2,2',4,5,5'-PENTACHLOROBIPHENYL
Systematic Name English
PCB 101
Common Name English
Code System Code Type Description
CAS
37680-73-2
Created by admin on Sat Dec 16 03:10:20 GMT 2023 , Edited by admin on Sat Dec 16 03:10:20 GMT 2023
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FDA UNII
803YVI5BNP
Created by admin on Sat Dec 16 03:10:20 GMT 2023 , Edited by admin on Sat Dec 16 03:10:20 GMT 2023
PRIMARY
PUBCHEM
37807
Created by admin on Sat Dec 16 03:10:20 GMT 2023 , Edited by admin on Sat Dec 16 03:10:20 GMT 2023
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EPA CompTox
DTXSID8038304
Created by admin on Sat Dec 16 03:10:20 GMT 2023 , Edited by admin on Sat Dec 16 03:10:20 GMT 2023
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