Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H5Cl5 |
| Molecular Weight | 326.433 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
ClC1=CC(=C(Cl)C=C1)C2=C(Cl)C=C(Cl)C(Cl)=C2
InChI
InChIKey=LAHWLEDBADHJGA-UHFFFAOYSA-N
InChI=1S/C12H5Cl5/c13-6-1-2-9(14)7(3-6)8-4-11(16)12(17)5-10(8)15/h1-5H
| Molecular Formula | C12H5Cl5 |
| Molecular Weight | 326.433 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Detection and measurement of the agonistic activities of PCBs and mono-hydroxylated PCBs to the constitutive androstane receptor using a recombinant yeast assay. | 2015-10 |
|
| Polychlorinated Biphenyls (PCB 101, 153, and 180) Impair Murine Macrophage Responsiveness to Lipopolysaccharide: Involvement of NF-κB Pathway. | 2015-09 |
|
| Non-dioxin-like polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) induce chondrocyte cell death through multiple pathways. | 2015-04-02 |
|
| Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. | 2015-04-01 |
|
| Lactational exposure to low levels of the six indicator non-dioxin-like polychlorinated biphenyls induces DNA damage and repression of neuronal activity, in juvenile male mice. | 2015-02-03 |
|
| Polychlorinated biphenyls (PCB 101, PCB 153 and PCB 180) alter leptin signaling and lipid metabolism in differentiated 3T3-L1 adipocytes. | 2014-09-15 |
|
| Role of the nuclear xenobiotic receptors CAR and PXR in induction of cytochromes P450 by non-dioxinlike polychlorinated biphenyls in cultured rat hepatocytes. | 2013-10-01 |
|
| Neurodevelopmental and behavioral toxicity via lactational exposure to the sum of six indicator non-dioxin-like-polychlorinated biphenyls (∑6 NDL-PCBs) in mice. | 2012-09-04 |
|
| Some OH-PCBs are more potent inhibitors of aromatase activity and (anti-) glucocorticoids than non-dioxin like (NDL)-PCBs and MeSO₂-PCBs. | 2011-10-10 |
|
| Genotoxic effects of polychlorinated biphenyls (PCB 153, 138, 101, 118) in a fish cell line (RTG-2). | 2011-08 |
|
| In vitro toxicity profiling of ultrapure non-dioxin-like polychlorinated biphenyl congeners and their relative toxic contribution to PCB mixtures in humans. | 2011-05 |
|
| Effects of non-dioxin-like polychlorinated biphenyl congeners (PCB 101, PCB 153 and PCB 180) alone or mixed on J774A.1 macrophage cell line: modification of apoptotic pathway. | 2011-04-10 |
|
| Non-dioxin-like PCBs interact with benzo[a]pyrene-induced p53-responses and inhibit apoptosis. | 2010-12-01 |
|
| Evaluation of an hPXR reporter gene assay for the detection of aquatic emerging pollutants: screening of chemicals and application to water samples. | 2010-01 |
|
| Determination of lead, cadmium, and persistent organic pollutants in wild and orchard-farm-grown fruit in northeastern Poland. | 2010 |
|
| Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells. | 2009-12-10 |
|
| Degradation of pentachlorobiphenyl by a sequential treatment using Pd coated iron and an aerobic bacterium (H1). | 2009-09 |
|
| Transactivation potencies of Baikal seal constitutive active/androstane receptor by persistent organic pollutants and brominated flame retardants. | 2009-08-15 |
|
| Cell death mechanisms in GT1-7 GnRH cells exposed to polychlorinated biphenyls PCB74, PCB118, and PCB153. | 2009-06-01 |
|
| Catalytic dechlorination of polychlorinated biphenyls in soil by palladium-iron bimetallic catalyst. | 2009-05-15 |
|
| Destruction of pentachlorobiphenyl in soil by supercritical CO(2) extraction coupled with polymer-stabilized palladium nanoparticles. | 2009-05 |
|
| An Assessment of Mutagenic Effect of 3, 3', 4, 4', 5 Pentachlorobiphenyl (PCB126) in Muta Mouse Fetuses. | 2009-04 |
|
| Immune cell counts and risks of respiratory infections among infants exposed pre- and postnatally to organochlorine compounds: a prospective study. | 2008-12-04 |
|
| Serum concentrations of indicator PCB congeners in the Czech adult population. | 2008-07 |
|
| Different effects of PCB101, PCB118, PCB138 and PCB153 alone or mixed in MCF-7 breast cancer cells. | 2008-07 |
|
| Pesticide contamination profiles of water, sediment and aquatic organisms in the effluent of Gaobeidian wastewater treatment plant. | 2008-07 |
|
| Relationship of thyroid hormone levels to levels of polychlorinated biphenyls, lead, p,p'- DDE, and other toxicants in Akwesasne Mohawk youth. | 2008-06 |
|
| Associations between prenatal exposure to polychlorinated biphenyls and neonatal thyroid-stimulating hormone levels in a Mexican-American population, Salinas Valley, California. | 2007-10 |
|
| Improved quality control in gas chromatography interfaced to stable isotope ratio mass spectrometry by application of derivative chromatography. | 2007-05-02 |
|
| [Metabolism of 2,2',4,5,5'-pentachlorobiphenyl (CB101) by liver microsomes of rats, hamsters and guinea pigs]. | 2007-05 |
|
| Optimization of separation and detection conditions for comprehensive two-dimensional gas chromatography--time-of-flight mass spectrometry analysis of polychlorinated dibenzo-p-dioxins and dibenzofurans. | 2007-03-23 |
|
| Bioaccumulation of 14C-PCB 101 and 14C-PBDE 99 in the marine planktonic copepod Calanus finmarchicus under different food regimes. | 2007-02 |
|
| Caffeine N3-demethylation (CYP1A2) in a population with an increased exposure to polychlorinated biphenyls. | 2006-12 |
|
| Tumor promoting potency of PCBs 28 and 101 in rat liver. | 2006-07-01 |
|
| Specific human CYP 450 isoform metabolism of a pentachlorobiphenyl (PCB-IUPAC# 101). | 2006-05-26 |
|
| Effects of PCBs and MeSO2-PCBs on adrenocortical steroidogenesis in H295R human adrenocortical carcinoma cells. | 2006-05 |
|
| Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1). | 2006-01 |
|
| Apoptosis in bovine cumulus-oocyte complexes after exposure to polychlorinated biphenyl mixtures during in vitro maturation. | 2005-12 |
|
| The decrease in level of serum thyroxine by 2,2',4,5,5'-pentachlorobiphenyl in rats and mice: no correlation with formation of methylsulfonyl metabolites. | 2005-11 |
|
| Species differences in the tissue distribution of catechol and methylsulphonyl metabolites of 2,4,5,2',5'-penta- and 2,3,4,2',3',6'-hexachlorobiphenyls in rats, mice, hamsters and guinea pigs. | 2005-01 |
|
| Metabolism of polychlorinated biphenyls by Gunn rats: identification and serum retention of catechol metabolites. | 2004-12 |
|
| A possible mechanism for decrease in serum thyroxine level by polychlorinated biphenyls in Wistar and Gunn rats. | 2004-10 |
|
| Retention indexes for temperature-programmed gas chromatography of polychlorinated biphenyls. | 2004-09-15 |
|
| An unrecognized source of PCB contamination in schools and other buildings. | 2004-07 |
|
| Lineage-specific effects of polychlorinated biphenyls (PCB) on gene expression in the rabbit blastocyst. | 2004-04-08 |
|
| Tumor promoters as inhibitors of apoptosis in rat hepatocytes. | 2004-04-01 |
|
| Ortho-substituted polychlorinated biphenyl (PCB) congeners (95 or 101) decrease pituitary response to thyrotropin releasing hormone. | 2003-09-30 |
|
| Proliferative effects of estradiol, progesterone, and two CB congeners and their metabolites on gray seal (Halichoerus grypus) uterine myocytes in vitro. | 2003-09 |
|
| Metabolic disturbances in fish exposed to sodium pentachlorophenate (NaPCP) and 3,3',4,4',5-pentachlorobiphenyl (PCB126), individually or combined. | 2002-08 |
|
| The hypothalamo-pituitary-thyroid (HPT) axis: a target of nonpersistent ortho-substituted PCB congeners. | 2002-01 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:17:11 GMT 2025
by
admin
on
Mon Mar 31 21:17:11 GMT 2025
|
| Record UNII |
803YVI5BNP
|
| Record Status |
Validated (UNII)
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| Record Version |
|
-
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37680-73-2
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803YVI5BNP
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37807
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DTXSID8038304
Created by
admin on Mon Mar 31 21:17:11 GMT 2025 , Edited by admin on Mon Mar 31 21:17:11 GMT 2025
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