CARBOSTYRIL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H7NO
Molecular Weight	145.158
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1NC2=C(C=CC=C2)C=C1

InChI

InChIKey=LISFMEBWQUVKPJ-UHFFFAOYSA-N

InChI=1S/C9H7NO/c11-9-6-5-7-3-1-2-4-8(7)10-9/h1-6H,(H,10,11)

HIDE SMILES / InChI

Molecular Formula	C9H7NO
Molecular Weight	145.158
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Analysis of gyrA mutations in quinolone-resistant and -susceptible Campylobacter jejuni isolates from retail poultry and human clinical isolates by non-radioactive single-strand conformation polymorphism analysis and DNA sequencing.	2004	15078520
Patterns of quinolone susceptibility in Campylobacter jejuni associated with different gyrA mutations.	2004 Apr	15203753
Hydrogen-bonded supramolecular motifs in 4,4'-bipyridinium 8-hydroxy-7-iodoquinoline-5-sulfonate dihydrate.	2004 Apr	15071237
[Resistance to quinolones and beta-lactams in Salmonella enterica due to mutations in topoisomerase-encoding genes, altered cell permeability and expression of an active efflux system].	2004 Apr	15056435
Sequence and transcriptional analysis of a gene cluster of Pseudomonas putida 86 involved in quinoline degradation.	2004 Apr 28	15094204
Urine phenol and myeloperoxidase index: an observation in benzene exposed subjects.	2004 Aug	15370219
Active site geometry and substrate recognition of the molybdenum hydroxylase quinoline 2-oxidoreductase.	2004 Aug	15296736
Epidemiological characteristics and molecular basis of fluoroquinolone-resistant Neisseria gonorrhoeae strains isolated in Korea and nearby countries.	2004 Aug	15231766
An unusually high level of quinolone resistance associated with type II topoisomerase mutations in quinolone resistance-determining regions of Aeromonas caviae isolated from diarrhoeal patients.	2004 Dec	15567276
Molecular characterization of clinical Streptococcus pneumoniae isolates with reduced susceptibility to fluoroquinolones emerging in Italy.	2004 Fall	15383164
Ciprofloxacin-resistant Salmonella enterica Typhimurium and Choleraesuis from pigs to humans, Taiwan.	2004 Jan	15078598
Molecular basis of quinolone resistance in Escherichia coli from wild birds.	2004 Jul	15352551
Type II topoisomerase mutations in Bacillus anthracis associated with high-level fluoroquinolone resistance.	2004 Jul	15190035
Quinolone resistance-determining region mutations and por type of Neisseria gonorrhoeae isolates: resistance surveillance and typing by molecular methodologies.	2004 Jun 1	15143477
Entrapment and release of quinoline derivatives using a hydrogel of a low molecular weight gelator.	2004 Jun 18	15196751
Biradicals/zwitterions from thermolysis of enyne-isocyanates. Application to the synthesis of 2(1H)-pyridones, benzofuro[3,2-c]pyridin-1(2H)-ones, 2,5-dihydro-1H-pyrido[4,3-b]indol-1-ones, and related compounds.	2004 Jun 25	15202908
Detection of mutations in the gyrA gene and class I integron from quinolone-resistant Salmonella enterica serovar Choleraesuis isolates in Taiwan.	2004 Jun 3	15145503
Geographically dependent distribution of gyrA gene mutations at codons 83 and 87 in Salmonella Hadar, and a novel codon 81 Gly to His mutation in Salmonella Enteritidis.	2004 Mar	15153158
Red-green-blue emission from tris(5-aryl-8-quinolinolate)Al(III) complexes.	2004 Mar 5	14987034
Characterization of a point mutation in the parC gene of Mycoplasma bovirhinis associated with fluoroquinolone resistance.	2004 May	15228551
[Study on the gene mutation of quinolone-resistant Mycobacterium tuberculosis isolated from Sichuan Province].	2004 May	15181822
Emergence of fluoroquinolone resistance in the native Campylobacter coli population of pigs exposed to enrofloxacin.	2004 May	15028665
The efficacy of some drugs with known antiprotozoal activity against Histomonas meleagridis in chickens.	2004 May 26	15135862
Bactericidal activity of garenoxacin tested by kill-curve methodology against wild type and QRDR mutant strains of Streptococcus pneumoniae.	2004 Nov	15541608
Electrophilic-induced cyclization reaction of hexahydroindolinone derivatives and its application toward the synthesis of (+/-)-erysotramidine.	2004 Nov 26	15549789
Fluoroquinolone resistance in penicillin-resistant Streptococcus pneumoniae clones, Spain.	2004 Oct	15504260
Genetic relatedness of ciprofloxacin-resistant Shigella dysenteriae type 1 strains isolated in south Asia.	2004 Oct	15347639
Excited-state proton transfer reactions of 10-hydroxycamptothecin.	2004 Oct 6	15453804
Multidrug resistance associated with mexXY expression in clinical isolates of Pseudomonas aeruginosa from a Texas hospital.	2004 Sep	15380277
Antimicrobial resistance of Neisseria gonorrhoeae in Japan, 1993-2002: continuous increasing of ciprofloxacin-resistant isolates.	2004 Sep	15364300
Mechanisms of quinolone resistance and clonal relationship among Aeromonas salmonicida strains isolated from reared fish with furunculosis.	2004 Sep	15314197
Carbostyril derivatives as antenna molecules for luminescent lanthanide chelates.	2004 Sep-Oct	15366964
Fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae from Asian countries: ANSORP study.	2004 Spring	15140392
Development of a real-time fluorescence resonance energy transfer PCR to identify the main pathogenic Campylobacter spp.	2005 Apr	15760424
Synthesis of 5-substituted-1H-indol-2-yl-1H-quinolin-2-ones: a novel class of KDR kinase inhibitors.	2005 Apr 1	15787543
Design, synthesis, and activity of achiral analogs of 2-quinolones and indoles as non-thiol farnesyltransferase inhibitors.	2005 Apr 15	15808463
[Antimicrobially effective compounded medications. Clinical value and critical comments].	2005 Aug	15933865
DNA gyrase gene in Neisseria gonorrhoeae as indicator for resistance to ciprofloxacin and species verification.	2005 Feb	15807943
Susceptibility of Campylobacter hyointestinalis subsp. hyointestinalis to antimicrobial agents and characterization of quinolone-resistant strains.	2005 Feb	15649999
Simultaneous determination of NSO-heterocycles, homocycles and their metabolites in groundwater of tar oil contaminated sites using LC with diode array UV and fluorescence detection.	2005 Feb 18	15782967
Isolation and molecular characterization of fluoroquinolone-resistant Escherichia coli from poultry litter.	2005 Jan	15685943
Reactivity and transformation of antibacterial N-oxides in the presence of manganese oxide.	2005 Jan 15	15707060
The molecular epidemiology of Streptococcus pneumoniae with quinolone resistance mutations.	2005 Jan 15	15655739
Rapid simultaneous determination of metabolic clearance of multiple compounds catalyzed in vitro by recombinant human UDP-glucuronosyltransferases.	2005 Jun 1	15866534
6-hydroxyquinoline-N-oxides: a new class of "super" photoacids.	2005 Jun 15	15941289
Benzimidazolones and indoles as non-thiol farnesyltransferase inhibitors based on tipifarnib scaffold: synthesis and activity.	2005 Jun 2	15911281
Discovery of powerful uranyl ligands from efficient synthesis and screening.	2005 Jun 6	15809989
Molecular characterization of a multidrug-resistant strain of enteroinvasive Escherichia coli O164 isolated in Japan.	2005 Mar	15713611
Design, microwave-assisted synthesis, and photophysical properties of small molecule organic antennas for luminescence resonance energy transfer.	2005 Mar-Apr	15762757
Parallel liquid-phase synthesis of N-substituted 6-aminosulfonyl-2-oxo-1,2-dihydroquinoline-4-carboxamide and 6-aminosulfonylquinoline-4-carboxamide derivatives.	2005 Mar-Apr	15762750

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:05:18 GMT 2023` Edited by `admin` on `Fri Dec 15 19:05:18 GMT 2023`
Record UNII	803BHY7QWU
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CARBOSTYRIL

Common Name

English

2-QUINOLINOL

Systematic Name

English

2(1H)-QUINOLONE

Systematic Name

English

2(1H)-QUINOLINONE

Systematic Name

English

O-AMINOCINNAMIC ACID LACTAM

Common Name

English

2-HYDROXYQUINOLINE

Systematic Name

English

CARBOSTYRIL [MI]

Common Name

English

NSC-156783

Code

English

HYDROXYQUINOLINE, 2-

Systematic Name

English

Code System Code Type Description

CHEBI

18289