NEMVALEUKIN ALFA

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 01:30:00 GMT 2025` Edited by `admin` on `Wed Apr 02 01:30:00 GMT 2025`
Protein Type	CYTOKINE
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	7ZX1Q9SJ1F
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NEMVALEUKIN ALFA

Official Name

English

ALKS-4230

Preferred Name

English

RDB-1450

Code

English

NEMVALEUKIN ALFA [USAN]

Common Name

English

ALKS4230

Code

English

Nemvaleukin alfa [WHO-DD]

Common Name

English

Fusion protein comprised of a circularly-permuted interleukin-2 (IL-2) with the extracellular domain of IL-2 receptor alpha

Common Name

English

nemvaleukin alfa [INN]

Common Name

English

human interleukin 2 fragment (1-59), variant (Cys125>Ser51), fused via peptidyl linker (60GG61) to human interleukin 2 fragment (62-132), fused via peptidyl linker (133GSGGGS138) to human interleukin 2 receptor ?-chain fragment (139-303), produced in Chi

Common Name

English

75-133-Interleukin 2 [125-serine] (human) fusion protein with peptide linker (GG) fusion protein with 4-74-interleukin 2 (human) fusion protein with peptide linker (GSGGGS) fusion protein with 1-165-interleukin 2 receptor ?-chain (human)

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

806020