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Details

Stereochemistry ACHIRAL
Molecular Formula C17H18ClN3O
Molecular Weight 315.797
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BUMETRIZOLE

SMILES

CC1=CC(=C(O)C(=C1)N2N=C3C=CC(Cl)=CC3=N2)C(C)(C)C

InChI

InChIKey=OCWYEMOEOGEQAN-UHFFFAOYSA-N
InChI=1S/C17H18ClN3O/c1-10-7-12(17(2,3)4)16(22)15(8-10)21-19-13-6-5-11(18)9-14(13)20-21/h5-9,22H,1-4H3

HIDE SMILES / InChI

Molecular Formula C17H18ClN3O
Molecular Weight 315.797
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Sources: ttps://www.ncbi.nlm.nih.gov/pubmed/20880230

Bumetrizole is an ultraviolet light absorber (UVA) of the hydroxyphenyl benzotriazole class, which imparts outstanding light stability to plastics and other organic substrates. Bumetrizole is also approved by the FDA as a stabilizer in polymers used in producing, manufacturing, packaging, processing, and transporting food. Bumetrizole has a wide range of indirect food approvals in polyolefins. It has a low volatility at high temperatures and high resistance to thermal degradation and can, therefore, be used without significant loss or decomposition in the polyolefin compounding and molding processes.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
2-tert-Butyl-6-[(4-chloro-2-nitro-phen-yl)diazen-yl]-4-methylphenol.
2009 Jun 6
Patents

Sample Use Guides

In Vivo Use Guide
Sources: ttps://www.ncbi.nlm.nih.gov/pubmed/20880230
The formulation containing the UV-filter combination, vitamin A and the Bumetrizole (0.05% w/w) was applied (5 mg/cm)2) on the dorsum of the animals once a day for 5 days to simulate a daily use condition
Route of Administration: Topical
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:03:46 GMT 2023
Edited
by admin
on Fri Dec 15 16:03:46 GMT 2023
Record UNII
7ZF18Q354W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BUMETRIZOLE
INCI   INN   USAN  
INCI   INN   USAN  
Official Name English
2-TERT-BUTYL-6-(5-CHLORO-2H-BENZOTRIAZOL-2-YL)-P-CRESOL
Common Name English
PHENOL, 2-(5-CHLORO-2H-BENZOTRIAZOL-2-YL)-6-(1,1-DIMETHYLETHYL)-4-METHYL-
Systematic Name English
BUMETRIZOLE [INCI]
Common Name English
bumetrizole [INN]
Common Name English
2-(3'-TERT-BUTYL-2'-HYDROXY-5'-METHYL- PHENYL)-5-CHLOROBENZOTRIAZOLE
Common Name English
BUMETRIZOLE [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C851
Created by admin on Fri Dec 15 16:03:46 GMT 2023 , Edited by admin on Fri Dec 15 16:03:46 GMT 2023
Code System Code Type Description
EVMPD
SUB05972MIG
Created by admin on Fri Dec 15 16:03:46 GMT 2023 , Edited by admin on Fri Dec 15 16:03:46 GMT 2023
PRIMARY
ChEMBL
CHEMBL1880325
Created by admin on Fri Dec 15 16:03:46 GMT 2023 , Edited by admin on Fri Dec 15 16:03:46 GMT 2023
PRIMARY
INN
4709
Created by admin on Fri Dec 15 16:03:46 GMT 2023 , Edited by admin on Fri Dec 15 16:03:46 GMT 2023
PRIMARY
CAS
3896-11-5
Created by admin on Fri Dec 15 16:03:46 GMT 2023 , Edited by admin on Fri Dec 15 16:03:46 GMT 2023
PRIMARY
EPA CompTox
DTXSID9036438
Created by admin on Fri Dec 15 16:03:46 GMT 2023 , Edited by admin on Fri Dec 15 16:03:46 GMT 2023
PRIMARY
PUBCHEM
62531
Created by admin on Fri Dec 15 16:03:46 GMT 2023 , Edited by admin on Fri Dec 15 16:03:46 GMT 2023
PRIMARY
ECHA (EC/EINECS)
223-445-4
Created by admin on Fri Dec 15 16:03:46 GMT 2023 , Edited by admin on Fri Dec 15 16:03:46 GMT 2023
PRIMARY
FDA UNII
7ZF18Q354W
Created by admin on Fri Dec 15 16:03:46 GMT 2023 , Edited by admin on Fri Dec 15 16:03:46 GMT 2023
PRIMARY
NCI_THESAURUS
C74400
Created by admin on Fri Dec 15 16:03:46 GMT 2023 , Edited by admin on Fri Dec 15 16:03:46 GMT 2023
PRIMARY
SMS_ID
100000088461
Created by admin on Fri Dec 15 16:03:46 GMT 2023 , Edited by admin on Fri Dec 15 16:03:46 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY