Canvuparatide

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 20:49:23 GMT 2025` Edited by `admin` on `Wed Apr 02 20:49:23 GMT 2025`
Protein Type	HORMONE
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	7YT49ZX2QZ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-32-Human parathyroid hormone, N-[N6-[N-(17-carboxy-1-oxoheptadecyl)-L-?-glutamyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-2-[2-(2-aminoethoxy)ethoxy]acetyl-L-?-glutamyl]-D-lysyl-N-methylglycyl]-32a-[N6-[N-(17-carboxy-1-oxoheptadecyl)-L-?

Preferred Name

English

Canvuparatide

Official Name

English

canvuparatide [INN]

Common Name

English

human parathyroid hormone (PTH) peptide fragment (1-32), N32-amide substituted at N2.1 with N6-[N-(17-{[N-(17-carboxyheptadecanoyl)-L-?-glutamyl]amino}-10-oxo-3,6,12,15-tetraoxa-9-azaheptadecan-1-oyl)-L-?-glutamyl]-D-lysy

Common Name

English

Code System Code Type Description

INN

13262

Created by admin on Wed Apr 02 20:49:23 GMT 2025 , Edited by admin on Wed Apr 02 20:49:23 GMT 2025

PRIMARY

CAS

2925554-87-4

Created by admin on Wed Apr 02 20:49:23 GMT 2025 , Edited by admin on Wed Apr 02 20:49:23 GMT 2025

PRIMARY

NCI_THESAURUS

C211746

Created by admin on Wed Apr 02 20:49:23 GMT 2025 , Edited by admin on Wed Apr 02 20:49:23 GMT 2025

PRIMARY

FDA UNII

7YT49ZX2QZ

Created by admin on Wed Apr 02 20:49:23 GMT 2025 , Edited by admin on Wed Apr 02 20:49:23 GMT 2025

PRIMARY

Related Record Type Details


					7YT49ZX2QZ

Canvuparatide

ACTIVE MOIETY

Comments:

parathyroid hormone analogue

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1]	SITE_SPECIFIC	S		Canvuparatide modified serine	UJQ6L4CV49
AMINO_ACID_SUBSTITUTION	[1_32]	SITE_SPECIFIC	H		Canvuparatide modified histidine	TN8U996MVN

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL