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Details

Stereochemistry UNKNOWN
Molecular Formula C18H36Cl2N4O2
Molecular Weight 411.41
Optical Activity UNSPECIFIED
Defined Stereocenters 0 / 4
E/Z Centers 0
Charge 2

SHOW SMILES / InChI
Structure of PROSPIDIUM

SMILES

OC(CCl)CN1CC[N+]2(CC1)CC[N+]3(CCN(CC(O)CCl)CC3)CC2

InChI

InChIKey=UVYDWIMQPVNRJN-UHFFFAOYSA-N
InChI=1S/C18H36Cl2N4O2/c19-13-17(25)15-21-1-5-23(6-2-21)9-11-24(12-10-23)7-3-22(4-8-24)16-18(26)14-20/h17-18,25-26H,1-16H2/q+2

HIDE SMILES / InChI

Molecular Formula C18H34Cl2N4O2
Molecular Weight 409.394
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 0 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

Prospidium is a diazoniadispiro(5.2.5.2)hexadecane derivative patented by All-Union Scientific-Research Chemical-Pharmaceutical Institute as an antitumor agent that does not inhibit hematopoiesis. In preclinical models, The injection of Prospidium to thyroidectomized and hypophysectomized rats inhibited tumor growth to a greater extent than in intact rats. Larynx and lung cancer, lymphogranulomatosis, leucosis, etc. can be successfully treated with Prospidium at doses of 60-120 mg daily.

Originator

Approval Year

PubMed

Substance Class Chemical
Record UNII
7Y2M0915RZ
Record Status Validated (UNII)
Record Version