Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C3H5NO2 |
| Molecular Weight | 87.0773 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
NC(=O)OC=C
InChI
InChIKey=LVLANIHJQRZTPY-UHFFFAOYSA-N
InChI=1S/C3H5NO2/c1-2-6-3(4)5/h2H,1H2,(H2,4,5)
| Molecular Formula | C3H5NO2 |
| Molecular Weight | 87.0773 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects. | 1991 Mar-Apr |
|
| Vinyl carbamate epoxide, a major strong electrophilic, mutagenic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate (urethane). | 1993 Mar |
|
| Chemopreventive effects of 2-(allylthio)pyrazine on hepatic lesion, mutagenesis and tumorigenesis induced by vinyl carbamate or vinyl carbamate epoxide. | 1998 Jul |
|
| Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes. | 2001 Mar |
|
| Carcinogenic induction directs the selection of allelic losses in mouse lung tumorigenesis. | 2002 Nov 15 |
|
| Prevention of mouse lung tumors and modulation of DNA methylation by combined treatment with budesonide and R115777 (ZarnestraMT). | 2006 Dec |
|
| A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice. | 2006 Feb 23 |
|
| Prevention of lung cancer progression by bexarotene in mouse models. | 2006 Mar 2 |
|
| Modulation by budesonide of DNA methylation and mRNA expression in mouse lung tumors. | 2007 Mar 1 |
|
| Oxidation of vinyl carbamate and formation of 1,N6-ethenodeoxyadenosine in murine lung. | 2007 May |
|
| Role of peroxisome proliferator-activated receptor gamma and its ligands in the treatment of hematological malignancies. | 2008 |
|
| Evidence of complete cellular repair of 1,N6-ethenoadenine, a mutagenic and potential damage for human cancer, revealed by a novel method. | 2008 Jun |
|
| Cancer is a preventable disease that requires major lifestyle changes. | 2008 Sep |
|
| Chiral Brønsted acid-catalyzed enantioselective three-component Povarov reaction. | 2009 Apr 8 |
|
| Triterpenoids CDDO-methyl ester or CDDO-ethyl amide and rexinoids LG100268 or NRX194204 for prevention and treatment of lung cancer in mice. | 2009 Dec |
|
| Inhibition of vinyl carbamate-induced lung tumors and Kras2 mutations by the garlic derivative diallyl sulfone. | 2009 Mar 9 |
|
| FoxO3a gene is a target of deletion in mouse lung adenocarcinoma. | 2009 Oct |
|
| Formation and repair of tobacco carcinogen-derived bulky DNA adducts. | 2010 Dec 20 |
|
| Alteration of microRNA expression in vinyl carbamate-induced mouse lung tumors and modulation by the chemopreventive agent indole-3-carbinol. | 2010 Feb |
|
| Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice. | 2010 Feb |
|
| Capsaicin: a novel chemopreventive molecule and its underlying molecular mechanisms of action. | 2010 Jan-Mar |
|
| NADPH oxidase limits innate immune responses in the lungs in mice. | 2010 Mar 16 |
|
| Structure of the 1,N(2)-etheno-2'-deoxyguanosine lesion in the 3'-G(epsilon dG)T-5' sequence opposite a one-base deletion. | 2010 Mar 30 |
|
| Mechanisms of lung tumorigenesis by ethyl carbamate and vinyl carbamate. | 2010 May |
|
| Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice. | 2010 Nov |
|
| Cigarette smoke induces C/EBP-β-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells. | 2010 Oct 29 |
|
| Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents. | 2011 Mar 24 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 16 20:52:30 UTC 2022
by
admin
on
Fri Dec 16 20:52:30 UTC 2022
|
| Record UNII |
7Y2431GOM5
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
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Systematic Name | English | ||
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Code | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
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NCI_THESAURUS |
C45175
Created by
admin on Fri Dec 16 20:52:30 UTC 2022 , Edited by admin on Fri Dec 16 20:52:30 UTC 2022
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| Code System | Code | Type | Description | ||
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15805-73-9
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27492
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27292
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C017963
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DTXSID3021433
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133266
Created by
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7Y2431GOM5
Created by
admin on Fri Dec 16 20:52:30 UTC 2022 , Edited by admin on Fri Dec 16 20:52:30 UTC 2022
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C29864
Created by
admin on Fri Dec 16 20:52:30 UTC 2022 , Edited by admin on Fri Dec 16 20:52:30 UTC 2022
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PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
METABOLIC ENZYME -> SUBSTRATE |
| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> METABOLITE | |||
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METABOLITE -> PARENT |
