Details
Stereochemistry | ACHIRAL |
Molecular Formula | C3H5NO2 |
Molecular Weight | 87.0773 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
NC(=O)OC=C
InChI
InChIKey=LVLANIHJQRZTPY-UHFFFAOYSA-N
InChI=1S/C3H5NO2/c1-2-6-3(4)5/h2H,1H2,(H2,4,5)
Molecular Formula | C3H5NO2 |
Molecular Weight | 87.0773 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
---|---|---|
Vinyl carbamate epoxide, a major strong electrophilic, mutagenic and carcinogenic metabolite of vinyl carbamate and ethyl carbamate (urethane). | 1993 Mar |
|
Chemopreventive effects of 2-(allylthio)pyrazine on hepatic lesion, mutagenesis and tumorigenesis induced by vinyl carbamate or vinyl carbamate epoxide. | 1998 Jul |
|
Genetic effects of exocyclic DNA adducts in vivo: heritable genetic damage in comparison with loss of heterozygosity in somatic cells. | 1999 |
|
Mutation of beta-catenin is an early event in chemically induced mouse hepatocellular carcinogenesis. | 1999 Aug 19 |
|
Chemoprevention of vinyl carbamate-induced lung tumors in strain A mice. | 2000 Dec |
|
Strain-related differences in bioactivation of vinyl carbamate and formation of DNA adducts in lungs of A/J, CD-1, and C57BL/6 mice. | 2001 Jan |
|
Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes. | 2001 Mar |
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Chemoprevention by lipoxygenase and leukotriene pathway inhibitors of vinyl carbamate-induced lung tumors in mice. | 2002 Aug 1 |
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Prevention of mouse lung tumors by budesonide and its modulation of biomarkers. | 2002 Jul |
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Carcinogenic induction directs the selection of allelic losses in mouse lung tumorigenesis. | 2002 Nov 15 |
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Effect of budesonide on the methylation and mRNA expression of the insulin-like growth factor 2 and c-myc genes in mouse lung tumors. | 2002 Oct |
|
Comparative prevalence, multiplicity, and progression of spontaneous and vinyl carbamate-induced liver lesions in five strains of male mice. | 2002 Sep-Oct |
|
Lipoxygenase and cyclooxygenase metabolism: new insights in treatment and chemoprevention of pancreatic cancer. | 2003 Jan 7 |
|
Carcinogen-specific targeting of chromosome 12 for loss of heterozygosity in mouse lung adenocarcinomas: implications for chromosome instability and tumor progression. | 2004 Apr 15 |
|
Interactions in the tumor-promoting activity of carbon tetrachloride, trichloroacetate, and dichloroacetate in the liver of male B6C3F1 mice. | 2004 Jul 1 |
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Chemoenzymatic synthesis and high-throughput screening of an aminoglycoside-polyamine library: identification of high-affinity displacers and DNA-binding ligands. | 2004 Oct 6 |
|
Chemoprevention: mouse colon and lung tumor bioassay and modulation of DNA methylation as a biomarker. | 2005 Mar |
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A mouse model for tumor progression of lung cancer in ras and p53 transgenic mice. | 2006 Feb 23 |
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Prevention of lung cancer progression by bexarotene in mouse models. | 2006 Mar 2 |
|
The synthetic triterpenoids CDDO-methyl ester and CDDO-ethyl amide prevent lung cancer induced by vinyl carbamate in A/J mice. | 2007 Mar 15 |
|
A new rexinoid, NRX194204, prevents carcinogenesis in both the lung and mammary gland. | 2007 Oct 15 |
|
Role of peroxisome proliferator-activated receptor gamma and its ligands in the treatment of hematological malignancies. | 2008 |
|
Evidence of complete cellular repair of 1,N6-ethenoadenine, a mutagenic and potential damage for human cancer, revealed by a novel method. | 2008 Jun |
|
The rexinoid LG100268 and the synthetic triterpenoid CDDO-methyl amide are more potent than erlotinib for prevention of mouse lung carcinogenesis. | 2008 May |
|
Structure of the 1,N2-ethenodeoxyguanosine adduct opposite cytosine in duplex DNA: Hoogsteen base pairing at pH 5.2. | 2008 Sep |
|
Cancer is a preventable disease that requires major lifestyle changes. | 2008 Sep |
|
Chiral Brønsted acid-catalyzed enantioselective three-component Povarov reaction. | 2009 Apr 8 |
|
Inhibition of vinyl carbamate-induced lung tumors and Kras2 mutations by the garlic derivative diallyl sulfone. | 2009 Mar 9 |
|
FoxO3a gene is a target of deletion in mouse lung adenocarcinoma. | 2009 Oct |
|
Mechanisms of lung tumorigenesis by ethyl carbamate and vinyl carbamate. | 2010 May |
|
Chemopreventive effects of pioglitazone on chemically induced lung carcinogenesis in mice. | 2010 Nov |
|
Cigarette smoke induces C/EBP-β-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells. | 2010 Oct 29 |
|
Tricyclic compounds containing nonenolizable cyano enones. A novel class of highly potent anti-inflammatory and cytoprotective agents. | 2011 Mar 24 |
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 16:42:26 UTC 2023
by
admin
on
Fri Dec 15 16:42:26 UTC 2023
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Record UNII |
7Y2431GOM5
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Record Status |
Validated (UNII)
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Record Version |
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Systematic Name | English | ||
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Code | English |
Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C45175
Created by
admin on Fri Dec 15 16:42:26 UTC 2023 , Edited by admin on Fri Dec 15 16:42:26 UTC 2023
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15805-73-9
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27492
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27292
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C017963
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DTXSID3021433
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admin on Fri Dec 15 16:42:26 UTC 2023 , Edited by admin on Fri Dec 15 16:42:26 UTC 2023
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133266
Created by
admin on Fri Dec 15 16:42:26 UTC 2023 , Edited by admin on Fri Dec 15 16:42:26 UTC 2023
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7Y2431GOM5
Created by
admin on Fri Dec 15 16:42:26 UTC 2023 , Edited by admin on Fri Dec 15 16:42:26 UTC 2023
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C29864
Created by
admin on Fri Dec 15 16:42:26 UTC 2023 , Edited by admin on Fri Dec 15 16:42:26 UTC 2023
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PRIMARY |
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