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Details

Stereochemistry ACHIRAL
Molecular Formula C4H10O2
Molecular Weight 90.121
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,4-BUTANEDIOL

SMILES

OCCCCO

InChI

InChIKey=WERYXYBDKMZEQL-UHFFFAOYSA-N
InChI=1S/C4H10O2/c5-3-1-2-4-6/h5-6H,1-4H2

HIDE SMILES / InChI

Molecular Formula C4H10O2
Molecular Weight 90.121
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Phase separation and physical properties of PEO-containing poly(ether ester amide)s.
2002
The effect of oxidation on the enzyme-catalyzed hydrolytic biodegradation of poly(urethane)s.
2002
Treatment of a 1,4-butanediol poisoning with fomepizole.
2002
Central effects of 1,4-butanediol are mediated by GABA(B) receptors via its conversion into gamma-hydroxybutyric acid.
2002 Apr 26
Simultaneous analysis of gamma-hydroxybutyric acid, gamma-butyrolactone, and 1,4-butanediol by micellar electrokinetic chromatography.
2002 Feb 18
Surface characterization and platelet adhesion studies of aliphatic polyurethanes grafted by fluorocarbon oligomers: effect of fluorocarbon chain length and carboxylic acid group.
2002 Jan
Gamma hydroxybutyric acid (GHB) intoxication.
2002 Jul
WBC filtration of whole blood after prolonged storage at ambient temperature by use of an in-line filter collection system.
2002 Jun
First preparation of spacer-linked cyclic neooligoaminodeoxysaccharides.
2002 Jun 17
Production of gamma-hydroxybutyric acid in postmortem liver increases with time after death.
2002 Mar 28
Recovery of small bioparticles by interfacial partitioning.
2002 May 20
Human macrophage-mediated biodegradation of polyurethanes: assessment of candidate enzyme activities.
2002 Oct
Evaluation of the reinforcing and discriminative stimulus effects of 1,4-butanediol and gamma-butyrolactone in rhesus monkeys.
2003 Apr 11
Thermodynamic parameters monitoring the equilibrium shift of enzyme-catalyzed hydrolysis/synthesis reactions in favor of synthesis in mixtures of water and organic solvent.
2003 Jan 20
Poly(ether ester amide)s for tissue engineering.
2003 Jul
Adenosine-5'-O-phosphorylated and adenosine-5'-O-phosphorothioylated polyols as strong inhibitors of (symmetrical) and (asymmetrical) dinucleoside tetraphosphatases.
2003 Jul 15
Lipase-catalyzed enantioselective esterification of (S)-naproxen hydroxyalkyl ester in organic media.
2003 Mar
Chiral direction and interconnection of helical three-connected networks in metal-organic frameworks.
2003 Mar 10
Through-shell alkyllithium additions and borane reductions.
2003 Mar 21
Synthesis and characterization of poly(butylene succinate-co-butylene malate): a new biodegradable copolyester bearing hydroxyl pendant groups.
2003 Mar-Apr
The role of GABAB receptors in the discriminative stimulus effects of gamma-hydroxybutyrate in rats: time course and antagonism studies.
2003 May
Intoxication due to 1,4-butanediol.
2003 May 5
Lipase-catalyzed polycondensations: effect of substrates and solvent on chain formation, dispersity, and end-group structure.
2003 May-Jun
Synthesis of double-headed 2-5A-antisense chimeras and their ability to activate human RNase L.
2003 Nov 17
Cellular interactions and degradation of aliphatic poly(ester amide)s derived from glycine and/or 4-amino butyric acid.
2003 Sep
Effects of temperature, inoculum size and starch hydrolyzate concentration on butanediol production by Bacillus licheniformis.
2003 Sep
The gamma-hydroxybutyrate withdrawal syndrome.
2004
Gamma-hydroxybutyrate: bridging the clinical-analytical gap.
2004
Gamma-butyrolactone and 1,4-butanediol: abused analogues of gamma-hydroxybutyrate.
2004
Design, synthesis and properties of a degradable polyurethane scaffold for meniscus regeneration.
2004 Apr
Comparison of the actions of gamma-butyrolactone and 1,4-butanediol in Swiss-Webster mice.
2004 Apr
Changes in macrophage function and morphology due to biomedical polyurethane surfaces undergoing biodegradation.
2004 Apr
The inkjet cleaner "Hurricane"--another GhB recipe.
2004 Dec
Interaction between 1,4-butanediol and ethanol on operant responding and the cardiovascular system.
2004 Dec 3
Determination of gamma-hydroxybutyric acid in biological fluids by using capillary electrophoresis with indirect detection.
2004 Feb 5
Development of a solid-phase extraction method for simultaneous extraction of adipic acid, succinic acid and 1,4-butanediol formed during hydrolysis of poly(butylene adipate) and poly(butylene succinate).
2004 Jan 2
Chronic 1,4-butanediol treatment in rats: cross-tolerance to gamma-hydroxybutyrate and (+/-)-baclofen.
2004 Jan 26
Influence of reinforcer type and route of administration on gamma-hydroxybutyrate discrimination in rats.
2004 Jul
Monolithic columns with mixed modes of reversed-phase and anion-exchange stationary phase for capillary electrochromatography.
2004 Jul 30
Discriminative stimulus effects of gamma-hydroxybutyrate in pigeons: role of diazepam-sensitive and -insensitive GABA(A) and GABA(B) receptors.
2004 Mar
Metabolic analysis of acetate accumulation during xylose consumption by Paenibacillus polymyxa.
2004 Mar
The Discriminative stimulus effects of gamma-hydroxybutyrate and related compounds in rats discriminating baclofen or diazepam: The role of GABA(B) and GABA(A) receptors.
2004 May
Simultaneous analysis of gamma-hydroxybutyric acid and its precursors in urine using liquid chromatography-tandem mass spectrometry.
2004 Nov 12
4-methylpyrazole decreases 1,4-butanediol toxicity by blocking its in vivo biotransformation to gamma-hydroxybutyric acid.
2004 Oct
Enhanced production of acetoin and butanediol in recombinant Enterobacter aerogenes carrying Vitreoscilla hemoglobin gene.
2004 Oct
GHB (gamma-hydroxybutyrate) carrier-mediated transport across the blood-brain barrier.
2004 Oct
Adsorption of naphthalene on zeolite from aqueous solution.
2004 Sep 1
Biodegradation of aliphatic homopolyesters and aliphatic-aromatic copolyesters by anaerobic microorganisms.
2004 Sep-Oct
Physical characterizations of microemulsion systems using tocopheryl polyethylene glycol 1000 succinate (TPGS) as a surfactant for the oral delivery of protein drugs.
2005 Feb 2
In vitro degradation of polyurethane orthodontic elastomeric modules.
2005 Jan
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 16 17:42:54 UTC 2022
Edited
by admin
on Fri Dec 16 17:42:54 UTC 2022
Record UNII
7XOO2LE6G3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
1,4-BUTANEDIOL
HSDB   INCI   MI  
INCI  
Official Name English
1,4-BUTANEDIOL [MI]
Common Name English
NSC-406696
Code English
1,4-BUTANEDIOL [HSDB]
Common Name English
1,4-BUTYLENE GLYCOL
Systematic Name English
1,4-TETRAMETHYLENE GLYCOL
Common Name English
BUTANE-1,4-DIOL
Systematic Name English
TETRAMETHYLENE GLYCOL
Systematic Name English
1,4-BUTANEDIOL [INCI]
Common Name English
1,4-DIHYDROXYBUTANE
Systematic Name English
Classification Tree Code System Code
WIKIPEDIA Designer-drugs-1,4-Butanediol
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
Code System Code Type Description
WIKIPEDIA
1,4-BUTANEDIOL
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY
FDA UNII
7XOO2LE6G3
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY
PUBCHEM
8064
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY
EPA CompTox
DTXSID2024666
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY
MERCK INDEX
M2788
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY Merck Index
CAS
110-63-4
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY
DRUG BANK
DB01955
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY
ECHA (EC/EINECS)
203-786-5
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY
HSDB
1112
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY
CHEBI
41189
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY
NSC
406696
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY
MESH
C039681
Created by admin on Fri Dec 16 17:42:54 UTC 2022 , Edited by admin on Fri Dec 16 17:42:54 UTC 2022
PRIMARY
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