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Details

Stereochemistry ACHIRAL
Molecular Formula C4H10O2
Molecular Weight 90.121
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,4-BUTANEDIOL

SMILES

OCCCCO

InChI

InChIKey=WERYXYBDKMZEQL-UHFFFAOYSA-N
InChI=1S/C4H10O2/c5-3-1-2-4-6/h5-6H,1-4H2

HIDE SMILES / InChI

Molecular Formula C4H10O2
Molecular Weight 90.121
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Surface characterization and platelet adhesion studies of aliphatic polyurethanes grafted by fluorocarbon oligomers: effect of fluorocarbon chain length and carboxylic acid group.
2002 Jan
Synthesis of double-headed 2-5A-antisense chimeras and their ability to activate human RNase L.
2003
Evaluation of the reinforcing and discriminative stimulus effects of 1,4-butanediol and gamma-butyrolactone in rhesus monkeys.
2003 Apr 11
Impact of ionic liquid physical properties on lipase activity and stability.
2003 Apr 9
Purification and characterization of novel salt-active acharan sulfate lyase from Bacteroides stercoris HJ-15.
2003 Aug
Poly(ether ester amide)s for tissue engineering.
2003 Jul
Vertically stratified flows in microchannels. Computational simulations and applications to solvent extraction and ion exchange.
2003 Jul 15
Adenosine-5'-O-phosphorylated and adenosine-5'-O-phosphorothioylated polyols as strong inhibitors of (symmetrical) and (asymmetrical) dinucleoside tetraphosphatases.
2003 Jul 15
Drosophila metabolize 1,4-butanediol into gamma-hydroxybutyric acid in vivo.
2003 Jul 25
[Synthesis, characterization and blood compatibility studies of biomedical aliphatic polyurethanes].
2003 Jun
Lipase-catalyzed enantioselective esterification of (S)-naproxen hydroxyalkyl ester in organic media.
2003 Mar
Through-shell alkyllithium additions and borane reductions.
2003 Mar 21
Synthesis and characterization of poly(butylene succinate-co-butylene malate): a new biodegradable copolyester bearing hydroxyl pendant groups.
2003 Mar-Apr
Intoxication due to 1,4-butanediol.
2003 May 5
Lipase-catalyzed polycondensations: effect of substrates and solvent on chain formation, dispersity, and end-group structure.
2003 May-Jun
Synthesis of double-headed 2-5A-antisense chimeras and their ability to activate human RNase L.
2003 Nov 17
Syntheses and physical characterization of new aliphatic triblock poly(L-lactide-b-butylene succinate-b-L-lactide)s bearing soft and hard biodegradable building blocks.
2003 Nov-Dec
New Zealand's first fatality linked to use of 1,4-butanediol (1,4-B, Fantasy): no evidence of coingestion or comorbidity.
2003 Oct 24
[Investigation of the cause of polyurethane catheter cracking during constant infusion of etoposide (VP-16) injection (2)--Analysis of ethanol eluting materials from catheter].
2003 Sep
Cellular interactions and degradation of aliphatic poly(ester amide)s derived from glycine and/or 4-amino butyric acid.
2003 Sep
Effects of temperature, inoculum size and starch hydrolyzate concentration on butanediol production by Bacillus licheniformis.
2003 Sep
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 30-2003. A 21-year-old man with sudden alteration of mental status.
2003 Sep 25
Production of L-2,3-butanediol by a new pathway constructed in Escherichia coli.
2004
The gamma-hydroxybutyrate withdrawal syndrome.
2004
Gamma-hydroxybutyrate: bridging the clinical-analytical gap.
2004
Gamma-butyrolactone and 1,4-butanediol: abused analogues of gamma-hydroxybutyrate.
2004
Design, synthesis and properties of a degradable polyurethane scaffold for meniscus regeneration.
2004 Apr
Comparison of the actions of gamma-butyrolactone and 1,4-butanediol in Swiss-Webster mice.
2004 Apr
Changes in macrophage function and morphology due to biomedical polyurethane surfaces undergoing biodegradation.
2004 Apr
The inkjet cleaner "Hurricane"--another GhB recipe.
2004 Dec
Butane-1,4-diyl bis(chloroacetate).
2004 Dec
Interaction between 1,4-butanediol and ethanol on operant responding and the cardiovascular system.
2004 Dec 3
Preparation of macrocyclic 15N-labelled oligoaminodeoxysaccharides as probes for RNA-binding.
2004 Dec 7
Determination of gamma-hydroxybutyric acid in biological fluids by using capillary electrophoresis with indirect detection.
2004 Feb 5
The crystal structures of Klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate.
2004 Jan 16
Development of a solid-phase extraction method for simultaneous extraction of adipic acid, succinic acid and 1,4-butanediol formed during hydrolysis of poly(butylene adipate) and poly(butylene succinate).
2004 Jan 2
Comparison of monolithic silica and polymethacrylate capillary columns for LC.
2004 Jul
Influence of reinforcer type and route of administration on gamma-hydroxybutyrate discrimination in rats.
2004 Jul
Monolithic columns with mixed modes of reversed-phase and anion-exchange stationary phase for capillary electrochromatography.
2004 Jul 30
Discriminative stimulus effects of gamma-hydroxybutyrate in pigeons: role of diazepam-sensitive and -insensitive GABA(A) and GABA(B) receptors.
2004 Mar
Metabolic analysis of acetate accumulation during xylose consumption by Paenibacillus polymyxa.
2004 Mar
Simultaneous analysis of gamma-hydroxybutyric acid and its precursors in urine using liquid chromatography-tandem mass spectrometry.
2004 Nov 12
4-methylpyrazole decreases 1,4-butanediol toxicity by blocking its in vivo biotransformation to gamma-hydroxybutyric acid.
2004 Oct
Enhanced production of acetoin and butanediol in recombinant Enterobacter aerogenes carrying Vitreoscilla hemoglobin gene.
2004 Oct
GHB (gamma-hydroxybutyrate) carrier-mediated transport across the blood-brain barrier.
2004 Oct
Adsorption of naphthalene on zeolite from aqueous solution.
2004 Sep 1
Optimization of binary porogen solvent composition for preparation of butyl methacrylate monoliths in capillary liquid chromatography.
2004 Sep 17
Biodegradation of aliphatic homopolyesters and aliphatic-aromatic copolyesters by anaerobic microorganisms.
2004 Sep-Oct
Physical characterizations of microemulsion systems using tocopheryl polyethylene glycol 1000 succinate (TPGS) as a surfactant for the oral delivery of protein drugs.
2005 Feb 2
In vitro degradation of polyurethane orthodontic elastomeric modules.
2005 Jan
Patents
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:38:26 GMT 2023
Edited
by admin
on Fri Dec 15 15:38:26 GMT 2023
Record UNII
7XOO2LE6G3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
1,4-BUTANEDIOL
HSDB   INCI   MI  
INCI  
Official Name English
1,4-BUTANEDIOL [MI]
Common Name English
NSC-406696
Code English
1,4-BUTANEDIOL [HSDB]
Common Name English
1,4-BUTYLENE GLYCOL
Systematic Name English
1,4-TETRAMETHYLENE GLYCOL
Common Name English
BUTANE-1,4-DIOL
Systematic Name English
TETRAMETHYLENE GLYCOL
Systematic Name English
1,4-BUTANEDIOL [INCI]
Common Name English
1,4-DIHYDROXYBUTANE
Systematic Name English
Classification Tree Code System Code
WIKIPEDIA Designer-drugs-1,4-Butanediol
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
Code System Code Type Description
WIKIPEDIA
1,4-BUTANEDIOL
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY
FDA UNII
7XOO2LE6G3
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY
PUBCHEM
8064
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY
EPA CompTox
DTXSID2024666
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY
MERCK INDEX
m2788
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY Merck Index
CAS
110-63-4
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY
DRUG BANK
DB01955
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY
ECHA (EC/EINECS)
203-786-5
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY
HSDB
1112
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY
CHEBI
41189
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY
NSC
406696
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY
MESH
C039681
Created by admin on Fri Dec 15 15:38:26 GMT 2023 , Edited by admin on Fri Dec 15 15:38:26 GMT 2023
PRIMARY
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