SALUTARIDINE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C19H21NO4
Molecular Weight	327.3743
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC=C2C[C@H]3N(C)CC[C@@]4(C=C(OC)C(=O)C=C34)C2=C1O

InChI

InChIKey=GVTRUVGBZQJVTF-YJYMSZOUSA-N

InChI=1S/C19H21NO4/c1-20-7-6-19-10-16(24-3)14(21)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19/h4-5,9-10,13,22H,6-8H2,1-3H3/t13-,19+/m1/s1

HIDE SMILES / InChI

Molecular Formula	C19H21NO4
Molecular Weight	327.3743
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures.	2010-11-18	21083930
[Alkaloids in stems and leaves of Stephania cepharantha].	2010-05	20707195
Engineering cofactor preference of ketone reducing biocatalysts: A mutagenesis study on a γ-diketone reductase from the yeast Saccharomyces cerevisiae serving as an example.	2010-04-14	20480039
Crystallization and preliminary X-ray diffraction analysis of salutaridine reductase from the opium poppy Papaver somniferum.	2010-02-01	20124713
Biochemistry and occurrence of o-demethylation in plant metabolism.	2010	21423357
Removal of substrate inhibition and increase in maximal velocity in the short chain dehydrogenase/reductase salutaridine reductase involved in morphine biosynthesis.	2009-09-25	19648114
CYP719B1 is salutaridine synthase, the C-C phenol-coupling enzyme of morphine biosynthesis in opium poppy.	2009-09-04	19567876
Mammalian cytochrome P450 enzymes catalyze the phenol-coupling step in endogenous morphine biosynthesis.	2009-09-04	19561069
Evolution of morphine biosynthesis in opium poppy.	2009-05-07	19665152
RNAi suppression of the morphine biosynthetic gene salAT and evidence of association of pathway enzymes.	2009-03	19359021
Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae.	2008-09	18690217
Online structural elucidation of alkaloids and other constituents in crude extracts and cultured cells of Nandina domestica by combination of LC-MS/MS, LC-NMR, and LC-CD analyses.	2008-08	18671433
Metabolic engineering of morphinan alkaloids by over-expression and RNAi suppression of salutaridinol 7-O-acetyltransferase in opium poppy.	2008-01	17854406
Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors.	2007-09-14	17616524
Molecular modeling and site-directed mutagenesis reveal the benzylisoquinoline binding site of the short-chain dehydrogenase/reductase salutaridine reductase.	2007-04	17337529
Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis.	2006-10	16968522
Morphinane alkaloids with cell protective effects from Sinomenium acutum.	2005-07	16038566
Saludimerines A and B, novel-type dimeric alkaloids with stereogenic centers and configurationally semistable biaryl axes.	2004-12-10	15575735
Transformation of opium poppy (Papaver somniferum L.) with antisense berberine bridge enzyme gene (anti-bbe) via somatic embryogenesis results in an altered ratio of alkaloids in latex but not in roots.	2004-12	15672841
Reticuline exposure to invertebrate ganglia increases endogenous morphine levels.	2004-10	15580165

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:25:29 GMT 2025` Edited by `admin` on `Mon Mar 31 21:25:29 GMT 2025`
Record UNII	7X10PRH74D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

(+)-SALUTARIDINE

Preferred Name

English

SALUTARIDINE

Common Name

English

MORPHINAN-7-ONE, 5,6,8,14-TETRADEHYDRO-4-HYDROXY-3,6-DIMETHOXY-17-METHYL-

Systematic Name

English

FLORIPAVINE

Common Name

English

SALUTARIDINE, (+)-

Common Name

English

SALUTARIDIN

Common Name

English

SALUTARIDINE [MI]

Common Name

English

Code System Code Type Description

FDA UNII

7X10PRH74D