Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C19H21NO4 |
| Molecular Weight | 327.3743 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C[C@]23CCN(C)[C@H](CC4=C2C(O)=C(OC)C=C4)C3=CC1=O
InChI
InChIKey=GVTRUVGBZQJVTF-YJYMSZOUSA-N
InChI=1S/C19H21NO4/c1-20-7-6-19-10-16(24-3)14(21)9-12(19)13(20)8-11-4-5-15(23-2)18(22)17(11)19/h4-5,9-10,13,22H,6-8H2,1-3H3/t13-,19+/m1/s1
| Molecular Formula | C19H21NO4 |
| Molecular Weight | 327.3743 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 2 / 2 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Transformation of opium poppy (Papaver somniferum L.) with antisense berberine bridge enzyme gene (anti-bbe) via somatic embryogenesis results in an altered ratio of alkaloids in latex but not in roots. | 2004 Dec |
|
| Saludimerines A and B, novel-type dimeric alkaloids with stereogenic centers and configurationally semistable biaryl axes. | 2004 Dec 10 |
|
| Reticuline exposure to invertebrate ganglia increases endogenous morphine levels. | 2004 Oct |
|
| Morphinane alkaloids with cell protective effects from Sinomenium acutum. | 2005 Jul |
|
| Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis. | 2006 Oct |
|
| Molecular modeling and site-directed mutagenesis reveal the benzylisoquinoline binding site of the short-chain dehydrogenase/reductase salutaridine reductase. | 2007 Apr |
|
| Live cell monitoring of mu-opioid receptor-mediated G-protein activation reveals strong biological activity of close morphine biosynthetic precursors. | 2007 Sep 14 |
|
| Online structural elucidation of alkaloids and other constituents in crude extracts and cultured cells of Nandina domestica by combination of LC-MS/MS, LC-NMR, and LC-CD analyses. | 2008 Aug |
|
| Metabolic engineering of morphinan alkaloids by over-expression and RNAi suppression of salutaridinol 7-O-acetyltransferase in opium poppy. | 2008 Jan |
|
| Production of benzylisoquinoline alkaloids in Saccharomyces cerevisiae. | 2008 Sep |
|
| RNAi suppression of the morphine biosynthetic gene salAT and evidence of association of pathway enzymes. | 2009 Mar |
|
| Evolution of morphine biosynthesis in opium poppy. | 2009 Oct-Nov |
|
| Removal of substrate inhibition and increase in maximal velocity in the short chain dehydrogenase/reductase salutaridine reductase involved in morphine biosynthesis. | 2009 Sep 25 |
|
| CYP719B1 is salutaridine synthase, the C-C phenol-coupling enzyme of morphine biosynthesis in opium poppy. | 2009 Sep 4 |
|
| Mammalian cytochrome P450 enzymes catalyze the phenol-coupling step in endogenous morphine biosynthesis. | 2009 Sep 4 |
|
| Biochemistry and occurrence of o-demethylation in plant metabolism. | 2010 |
|
| Engineering cofactor preference of ketone reducing biocatalysts: A mutagenesis study on a γ-diketone reductase from the yeast Saccharomyces cerevisiae serving as an example. | 2010 Apr 14 |
|
| Crystallization and preliminary X-ray diffraction analysis of salutaridine reductase from the opium poppy Papaver somniferum. | 2010 Feb 1 |
|
| [Alkaloids in stems and leaves of Stephania cepharantha]. | 2010 May |
|
| Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures. | 2010 Nov 18 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 04:59:41 GMT 2023
by
admin
on
Sat Dec 16 04:59:41 GMT 2023
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| Record UNII |
7X10PRH74D
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| Record Status |
Validated (UNII)
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| Record Version |
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7X10PRH74D
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m9749
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58061
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1936-18-1
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SALUTARIDINE
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