U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 22:56:55 UTC 2021
Edited
by admin
on Sat Jun 26 22:56:55 UTC 2021
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type TOXIN CONJUGATE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
7W0O278T12
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SERCLUTAMAB TALIRINE
INN   USAN  
Official Name English
ABBV-321
Code English
IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS EGFR (EPIDERMAL GROWTH FACTOR RECEPTOR, RECEPTOR TYROSINE-PROTEIN KINASE ERBB-1, ERBB1, HER1, HER-1, ERBB)), MONOCLONAL ANTIBODY CONJUGATED TO THE PYRROLOBENZODIAZEPINE (PDB) DIMER SGD-1882GAMMA1 HEAVY CHAIN (1
Common Name English
SERCLUTAMAB TALIRINE [INN]
Common Name English
ANTI-EGFR/PBD ANTIBODY-DRUG CONJUGATE ABBV-321
Common Name English
SERCLUTAMAB TALIRINE [USAN]
Common Name English
Code System Code Type Description
NCI_THESAURUS
C150590
Created by admin on Sat Jun 26 22:56:56 UTC 2021 , Edited by admin on Sat Jun 26 22:56:56 UTC 2021
PRIMARY
CAS
2140174-56-5
Created by admin on Sat Jun 26 22:56:56 UTC 2021 , Edited by admin on Sat Jun 26 22:56:56 UTC 2021
PRIMARY
INN
10959
Created by admin on Sat Jun 26 22:56:56 UTC 2021 , Edited by admin on Sat Jun 26 22:56:56 UTC 2021
PRIMARY
FDA UNII
7W0O278T12
Created by admin on Sat Jun 26 22:56:56 UTC 2021 , Edited by admin on Sat Jun 26 22:56:56 UTC 2021
PRIMARY
From To
1_22 1_96
1_143 1_199
1_219 3_214
1_225 2_225
1_228 2_228
1_260 1_320
1_366 1_424
2_22 2_96
2_143 2_199
2_219 4_214
2_260 2_320
2_366 2_424
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Link Type Site
N 1_296
N 2_296
Related Record Type Details
CONJUGATE COMPONENT->CONJUGATE
TARGET->CONJUGATED TOXIN
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL