INDIUM IN-111 SATUMOMAB PENDETIDE

Description
Sources: https://www.drugbank.ca/drugs/DB09425 | https://www.drugs.com/mmx/indium-in-111-pentetate.html

Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column. Indium In 111 pentetate ( 111In-DTPA) is indicated as an imaging agent in cisternography to study the flow of cerebrospinal fluid (CSF) in the brain, to diagnose abnormalities in CSF circulation, to assess and help localize the site of CSF leakage, and to test the patency of or localize blocks in CSF shunts.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
hydrocephalus 8 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8429	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982
syringomyelia 8 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8429	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982
arachnoid cyst 8 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8429	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982

Sample Use Guides

In Vivo Use Guide

The maximum recommended intrathecal dose in the average patient (70 kg) is 18.5 MBq, 500 μCi. The patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration.

Route of Administration: Other

Substance Class	Protein Created by `admin` on `Sat Dec 16 10:05:16 GMT 2023` Edited by `admin` on `Sat Dec 16 10:05:16 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	MOUSE
Sequence Type	COMPLETE
Record UNII	7V9926378A
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

INDIUM IN-111 SATUMOMAB PENDETIDE

Common Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN TUMOR-ASSOCIATED GLYCOPROTEIN 72) (MOUSE MONOCLONAL B72.3 .GAMMA.1-CHAIN), DISULFIDE WITH MOUSE MONOCLONAL B72.3 LIGHT CHAIN, DIMER, N6-(N-(2-((2-(BIS(CARBOXYMETHYL)AMINO)ETHYL)(CARBOXYMETHYL)AMINO)ETHYL)-N-(CARBOXYMETHYL)G

Systematic Name

English

INDIUM IN 111 CYT-103

Code

English

INDIUM IN 111 SATUMOMAB PENDETIDE [USAN]

Common Name

English

CYT-103

Code

English

IMMUNOGLOBULIN G 1 (MOUSE MONOCLONAL B72.3 ANTI-HUMAN GLYCOPROTEIN TAG-72), DISULFIDE WITH MOUSE MONOCLONAL B72.3 LIGHT CHAIN, DIMER, N(SUP 6)-(N-(2-((2-(BIS(CARBOXYMETHYL)AMINO)ETHYL)(CARBOXYMETHYL)AMINO)ETHYL)-N-(CARBOXYMETHYL)GLYCYL)-N(SUP 2)-(N-GLYCY

Systematic Name

English

CYT-103 (111IN)

Code

English

IMMUNOGLOBULIN G 1 (MOUSE MONOCLONAL B72.3 ANTI-HUMAN GLYCOPROTEIN TAG-72), DISULPHIDE WITH MOUSE MONOCLONAL B72.3 LIGHT CHAIN, DIMER, N(SUP 6)-(N-(2-((2-(BIS(CARBOXYMETHYL)AMINO)ETHYL)(CARBOXYMETHYL)AMINO)ETHYL)-N-(CARBOXYMETHYL)GLYCYL)-N(SUP 2)-(N-GLYC

Systematic Name

English

IN-111 CYT-103

Code

English

ONCOSCINT

Brand Name

English

CYT-099

Code

English

INDIUM IN 111 SATUMOMAB PENDETIDE [USP IMPURITY]

Common Name

English

INDIUM IN 111 SATUMOMAB PENDETIDE

Official Name

English

SATUMOMAB PENDETIDE INDIUM IN-111

Common Name

English

INDIUM IN 111 SATUMOMAB PENDETIDE [MI]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

36789