U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Tue Apr 01 17:46:34 GMT 2025
Edited
by admin
on Tue Apr 01 17:46:34 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
7V632RH47W
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
HISTONE-LYSINE N-METHYLTRANSFERASE SETD2
Common Name English
HIF1
Preferred Name English
KMT3A
Common Name English
KIAA1732
Common Name English
SET2
Common Name English
HYPB
Common Name English
Code System Code Type Description
UNIPROT
Q9BYW2
Created by admin on Tue Apr 01 17:46:34 GMT 2025 , Edited by admin on Tue Apr 01 17:46:34 GMT 2025
PRIMARY
FDA UNII
7V632RH47W
Created by admin on Tue Apr 01 17:46:34 GMT 2025 , Edited by admin on Tue Apr 01 17:46:34 GMT 2025
PRIMARY
PHAROS
Q9BYW2
Created by admin on Tue Apr 01 17:46:34 GMT 2025 , Edited by admin on Tue Apr 01 17:46:34 GMT 2025
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
Inhibitor of the enzymatic activity of histone methyltransferase (HMT) Su(var)3-9, Enhancer-of-zeste, Trithorax domain containing 2 (SETD2), also known as KMT3A. SETD2 catalyzes the S-(5?-Adenosyl)-L-methionine (SAM)-dependent deposition of the third or final methyl group onto the di-methylated state of lysine 36 of histone H3 (H3K36me2) yielding the tri-methylated state of lysine 36 of histone H3 (H3K36me3)
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL