INDIUM IN-111 PENTETATE DISODIUM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C14H18N3O10.In.2Na
Molecular Weight	545.1915
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of INDIUM IN-111 PENTETATE DISODIUM

Structure Search

SMILES

[Na+].[Na+].[111In+3].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CCN(CC([O-])=O)CC([O-])=O

InChI

InChIKey=JKGXLBAWNSPIFF-LWQDMHIUSA-I

InChI=1S/C14H23N3O10.In.2Na/c18-10(19)5-15(1-3-16(6-11(20)21)7-12(22)23)2-4-17(8-13(24)25)9-14(26)27;;;/h1-9H2,(H,18,19)(H,20,21)(H,22,23)(H,24,25)(H,26,27);;;/q;+3;2*+1/p-5/i;1-4;;

HIDE SMILES / InChI

Molecular Formula	In
Molecular Weight	110.9051
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C14H18N3O10
Molecular Weight	388.3068
Charge	-5
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugbank.ca/drugs/DB09425 | https://www.drugs.com/mmx/indium-in-111-pentetate.html

Indium In-111 pentetate disodium is a radioactive diagnostic indicated for use in radionuclide cisternography. Decay of In-111 by electron capture allows for detection with a gamma camera for visualization of the brain and spinal column. Indium In 111 pentetate ( 111In-DTPA) is indicated as an imaging agent in cisternography to study the flow of cerebrospinal fluid (CSF) in the brain, to diagnose abnormalities in CSF circulation, to assess and help localize the site of CSF leakage, and to test the patency of or localize blocks in CSF shunts.

Approval Year

Conditions

Condition	Modality	Highest Phase	Product
hydrocephalus 8 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8429	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982
syringomyelia 8 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8429	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982
arachnoid cyst 8 Sources: http://www.nuclearonline.org/PI/Nycomed%20%20Indium%20DTPA%20In%20111.pdf	Diagnostic	Approved 8429	MPI INDIUM DTPA IN 111 Approved Use Unknown Launch Date 1982

Sample Use Guides

In Vivo Use Guide

The maximum recommended intrathecal dose in the average patient (70 kg) is 18.5 MBq, 500 μCi. The patient dose should be measured by a suitable radioactivity calibration system immediately prior to administration.

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:42:27 GMT 2023` Edited by `admin` on `Fri Dec 15 15:42:27 GMT 2023`
Record UNII	7UIT3ZGC8E
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

INDIUM IN-111 PENTETATE DISODIUM

Common Name

English

PENTETATE INDIUM DISODIUM,IN-111

Common Name

English

PENTETATE INDIUM DISODIUM IN 111

Official Name

English

DISODIUM (N,N-BIS(2-(BIS(CARBOXYMETHYL)AMINO)ETHYL)GLYCINATO(5-))INDATE(2-)-(SUP 111)IN

Common Name

English

Disodium [N,N-bis[2-[bis(carboxymethyl)amino]ethyl]glycinato(5-)]indate(2-)-111In

Common Name

English

PENTETATE INDIUM DISODIUM,IN-111 [VANDF]

Common Name

English

PENTETATE INDIUM DISODIUM IN 111 [USAN]

Common Name

English

INDIUM IN-111 PENTETATE DISODIUM [ORANGE BOOK]

Common Name

English

PENTETATE INDIUM DISODIUM, IN-111

Common Name

English

INDIUM (IN111) DISODIUM PENTETATE

Common Name

English

Indium (111 in) disodium pentetate [WHO-DD]

Common Name

English

PENTETATE INDIUM DISODIUM IN-111

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C2124