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Details

Stereochemistry ACHIRAL
Molecular Formula C9H8O
Molecular Weight 132.1592
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of 1,2-BENZOPYRAN

SMILES

C1OC2=CC=CC=C2C=C1

InChI

InChIKey=KYNSBQPICQTCGU-UHFFFAOYSA-N
InChI=1S/C9H8O/c1-2-6-9-8(4-1)5-3-7-10-9/h1-6H,7H2

HIDE SMILES / InChI
Molecular Formula C9H8O
Molecular Weight 132.1592
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
3-Acetyl-4-hy-droxy-6,7-dimethyl-2H-chromen-2-one.
2010-11-13
New 4H-chromen-4-one and 2H-chromene derivatives as anti-picornavirus capsid-binders.
2010-09-01
Small molecule screening in zebrafish: an in vivo approach to identifying new chemical tools and drug leads.
2010-06-12
3-{2-[2-(3-Hy-droxy-benzyl-idene)hydrazin-1-yl]-1,3-thia-zol-4-yl}-2H-chromen-2-one hemihydrate.
2010-05-29
(E)-1-[1-(6-Bromo-2-oxo-2H-chromen-3-yl)ethyl-idene]thio-semicarbazide.
2010-05-29
Phorbaketals A, B, and C, sesterterpenoids with a spiroketal of hydrobenzopyran moiety isolated from the marine sponge Phorbas sp.
2009-12-17
A novel chelatofore functionalized spiropyran of the 2-oxaindane series.
2009-12
Effects of diumancal and decursinol on 5-hydroxytryptamine level in rat brain.
2009-09
Synthesis and pharmacological evaluation of coumarin derivatives as cannabinoid receptor antagonists and inverse agonists.
2009-04-01
A forward chemical screen using zebrafish embryos with novel 2-substituted 2H-chromene derivatives.
2009-03
Synthesis, IR, UV/vis-, (1)H NMR and DFT study of chelatophore functionalized 1,3-benzoxazinone spiropyrans.
2008-12-01
Direct stereocontrolled synthesis of polyoxygenated hydrobenzofurans and hydrobenzopyrans from p-peroxy quinols.
2007-11-22
Chaetopyranin, a benzaldehyde derivative, and other related metabolites from Chaetomium globosum, an endophytic fungus derived from the marine red alga Polysiphonia urceolata.
2006-11
Efficient photochemical merocyanine-to-spiropyran ring closure mechanism through an extended conical intersection seam. A model CASSCF/CASPT2 study.
2006-03-23
The ring-opening reaction of chromenes: a photochemical mode-dependent transformation.
2005-10-06
Synthesis and structure-activity relationships of analogs of EM-652 (acolbifene), a pure selective estrogen receptor modulator. Study of nitrogen substitution.
2005-04
Phenylboronic acid mediated triple condensation reactions of phloroglucinol and unsaturated carbonyl compounds.
2005-02-03
Total synthesis of the highly potent anti-HIV natural product daurichromenic acid along with its two chromane derivatives, rhododaurichromanic acids A and B.
2003-11-13
A novel class of endothelin-A receptor antagonists, (R)-2-(benzo[1,3]dioxol-5-yl)-6-isopropyloxy-2H-chromene-3-carboxylic acids (S-1255). Conformational analysis of basic structure, crucial for ET(A) antagonism, in solution and solid states.
2002-12
Structure-activity relationships of a novel class of endothelin-A receptor antagonists and discovery of potent and selective receptor antagonist, 2-(benzo[1,3]dioxol-5-yl)-6-isopropyloxy-4-(4-methoxyphenyl)-2H-chromene-3-carboxylic acid (S-1255). 1. Study on structure-activity relationships and basic structure crucial for ET(A) antagonism.
2002-05-09
Electrocyclic ring closure of the enols of vinyl quinones. A 2H-chromene synthesis.
2001-11-29
Patents

Patents

JP1070598A
1
JP1070600A
1
JP2000035410A
1
JP2000053717A
1
JP2000053718A
1
JP2000103789A
1
JP2001039220A
1
JP2001046964A
1
JP2001146077A
1
JP2002185731A
1
JP2002317911A
1
JP2003524620A
19
JP2004018854A
1
JP2005528133A
1
JP2007139754A
1
JP2007505948A
1
JP2007508372A
1
JP2007520757A
1
JP2008082951A
1
JP2009145320A
1
JP2011195714A
1
JP2011226320A
1
JP4248787B2
1
JP4249984B2
1
JPH00726282A
1
JPH01186884A
1
JPH02120369A
1
JPH02218372A
1
JPH02233675A
1
JPH02258781A
1
JPH04117459A
1
JPH0412243A
1
JPH04283595A
1
JPH04310335A
1
JPH05156247A
1
JPH05232072A
1
JPH05281181A
1
JPH0568688A
1
JPH06157628A
1
JPH06166900A
1
JPH069627A
1
JPH07178152A
1
JPH07218717A
1
JPH0782262A
1
JPH0812806A
1
JPH08143685A
1
JPH08209030A
1
JPH08216330A
1
JPH08247190A
1
JPH08511002A
1
JPH09106065A
1
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:29:16 GMT 2025
Edited
by admin
on Mon Mar 31 19:29:16 GMT 2025
Record UNII
7U3W6XRV5U
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
1,2-BENZOPYRAN
MI  
Common Name English
1,2-BENZOPYRAN [MI]
Preferred Name English
1,2-CHROMENE
Common Name English
3-CHROMENE
Common Name English
2H-1-BENZOPYRAN
Systematic Name English
Code System Code Type Description
PUBCHEM
9211
Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025
PRIMARY
FDA UNII
7U3W6XRV5U
Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025
PRIMARY
MERCK INDEX
m2375
Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025
PRIMARY Merck Index
CAS
254-04-6
Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025
PRIMARY
WIKIPEDIA
Benzopyran
Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025
PRIMARY
EPA CompTox
DTXSID80180051
Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025
PRIMARY
CHEBI
35601
Created by admin on Mon Mar 31 19:29:16 GMT 2025 , Edited by admin on Mon Mar 31 19:29:16 GMT 2025
PRIMARY
NIH
NCATS
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