TOLFAMIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H12N3O2P
Molecular Weight	213.1735
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TOLFAMIDE

Structure Search

SMILES

CC1=C(C=CC=C1)C(=O)NP(N)(N)=O

InChI

InChIKey=NTZDIRFODDGCIF-UHFFFAOYSA-N

InChI=1S/C8H12N3O2P/c1-6-4-2-3-5-7(6)8(12)11-14(9,10)13/h2-5H,1H3,(H5,9,10,11,12,13)

HIDE SMILES / InChI

Molecular Formula	C8H12N3O2P
Molecular Weight	213.1735
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: Elks, J. (2014) The Dictionary of Drugs: Chemical Data, page 1215, retrieved from: https://books.google.ru/books?id=0vXTBwAAQBAJ | Morton, I.K., Hall, J.M. (2012) Concise Dictionary of Pharmacological Agents, page 277, retrieved from: https://books.google.ru/books?id=tsjrCAAAQBAJ | Korolkovas, A. (1998) Essentials of Medicinal Chemistry, page 938, retrieved from: https://books.google.ru/books?id=6hxtAAAAMAAJ

Tolfamide is a benzamide and urease enzyme inhibitor.

Approval Year

Patents

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:54:55 GMT 2023` Edited by `admin` on `Fri Dec 15 15:54:55 GMT 2023`
Record UNII	7TJT8X832U
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

TOLFAMIDE

Official Name

English

TOLFAMIDE [USAN]

Common Name

English

N-(Diaminophosphinyl)-O-toluamide

Systematic Name

English

EU-4584

Code

English

tolfamide [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C471

Created by admin on Fri Dec 15 15:54:55 GMT 2023 , Edited by admin on Fri Dec 15 15:54:55 GMT 2023

Code System Code Type Description

PUBCHEM

3085434

Created by admin on Fri Dec 15 15:54:55 GMT 2023 , Edited by admin on Fri Dec 15 15:54:55 GMT 2023

PRIMARY

INN

4841

Created by admin on Fri Dec 15 15:54:55 GMT 2023 , Edited by admin on Fri Dec 15 15:54:55 GMT 2023

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NCI_THESAURUS

C72870

Created by admin on Fri Dec 15 15:54:55 GMT 2023 , Edited by admin on Fri Dec 15 15:54:55 GMT 2023

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EVMPD

SUB11154MIG

Created by admin on Fri Dec 15 15:54:55 GMT 2023 , Edited by admin on Fri Dec 15 15:54:55 GMT 2023

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ChEMBL

CHEMBL2107099

Created by admin on Fri Dec 15 15:54:55 GMT 2023 , Edited by admin on Fri Dec 15 15:54:55 GMT 2023

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EPA CompTox

DTXSID20221053

Created by admin on Fri Dec 15 15:54:55 GMT 2023 , Edited by admin on Fri Dec 15 15:54:55 GMT 2023

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SMS_ID

100000077773

Created by admin on Fri Dec 15 15:54:55 GMT 2023 , Edited by admin on Fri Dec 15 15:54:55 GMT 2023

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CAS

70788-29-3

Created by admin on Fri Dec 15 15:54:55 GMT 2023 , Edited by admin on Fri Dec 15 15:54:55 GMT 2023

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FDA UNII

7TJT8X832U

Created by admin on Fri Dec 15 15:54:55 GMT 2023 , Edited by admin on Fri Dec 15 15:54:55 GMT 2023

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Related Record Type Details


					7TJT8X832U

TOLFAMIDE

ACTIVE MOIETY