Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H20NO4 |
| Molecular Weight | 338.3771 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 1 |
SHOW SMILES / InChI
SMILES
COC1=C(O)C=C2C(CC[N+]3=C2C=C4C=CC(OC)=C(OC)C4=C3)=C1
InChI
InChIKey=YYFOFDHQVIODOQ-UHFFFAOYSA-O
InChI=1S/C20H19NO4/c1-23-18-5-4-12-8-16-14-10-17(22)19(24-2)9-13(14)6-7-21(16)11-15(12)20(18)25-3/h4-5,8-11H,6-7H2,1-3H3/p+1
| Molecular Formula | C20H19NO4 |
| Molecular Weight | 337.3692 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Columbamine suppresses the proliferation and neovascularization of metastatic osteosarcoma U2OS cells with low cytotoxicity. | 2012-12-17 |
|
| Metabolites of protoberberine alkaloids in human urine following oral administration of Coptidis Rhizoma decoction. | 2010-11 |
|
| Dig1 protects against cell death provoked by glyphosate-based herbicides in human liver cell lines. | 2010-10-27 |
|
| [Simultaneous determination of six alkaloids in Coptis chinensis of different regions by RP-HPLC]. | 2010-10 |
|
| Anti-inflammatory and anti-nociceptive activities of compounds from Tinospora sagittata (Oliv.) Gagnep. | 2010-07 |
|
| Alkaloids from Fissistigma latifolium (Dunal) Merr. | 2010-06-24 |
|
| Metabolic diversification of benzylisoquinoline alkaloid biosynthesis through the introduction of a branch pathway in Eschscholzia californica. | 2010-06 |
|
| Quaternary alkaloids of Argemone mexicana. | 2010-02 |
|
| Significant differences in alkaloid content of Coptis chinensis (Huanglian), from its related American species. | 2009-08-24 |
|
| [A new flavonoid glucoside from Huanglianjiedutang decoction]. | 2009-05 |
|
| Inhibitory Effects of Coptidis rhizoma and Berberine on Cocaine-induced Sensitization. | 2009-03 |
|
| [Studies on chemical constituents in the anti-myocardial ischemia effective fraction of Corydalis yanhusuo]. | 2008-11 |
|
| Isoquinoline alkaloids isolated from Corydalis yanhusuo and their binding affinities at the dopamine D1 receptor. | 2008-09-25 |
|
| [Analysis of the main components of coptis-evodia herb couple by HPLC-DAD-MS]. | 2008-03 |
|
| Free radical scavenging activity and lipoxygenase inhibition of Mahonia aquifolium extract and isoquinoline alkaloids. | 2007-07-16 |
|
| High performance liquid chromatography-mass spectrometry analysis of protoberberine alkaloids in medicine herbs. | 2007-04 |
|
| Simultaneous determination of eight components in Radix Tinosporae by high-performance liquid chromatography coupled with diode array detector and electrospray tandem mass spectrometry. | 2007-02-19 |
|
| Characterization of isoquinoline alkaloids, diterpenoids and steroids in the Chinese herb Jin-Guo-Lan (Tinospora sagittata and Tinospora capillipes) by high-performance liquid chromatography/electrospray ionization with multistage mass spectrometry. | 2006 |
|
| Separation of protoberberine quaternary alkaloids from a crude extract of Enantia chlorantha by centrifugal partition chromatography. | 2004-07-02 |
|
| A comparative study on the anti-inflammatory, antinociceptive and antipyretic effects of isoquinoline alkaloids from the roots of Turkish Berberis species. | 2002-12-27 |
|
| Molecular cloning of columbamine O-methyltransferase from cultured Coptis japonica cells. | 2002-11 |
|
| Evaluation of natural products as inhibitors of human immunodeficiency virus type 1 (HIV-1) reverse transcriptase. | 1991-01-01 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:53:33 GMT 2025
by
admin
on
Mon Mar 31 19:53:33 GMT 2025
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| Record UNII |
7T4808FEJW
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| Record Status |
Validated (UNII)
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| Record Version |
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m3745
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C055786
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