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Details

Stereochemistry ACHIRAL
Molecular Formula C17H16N2O3S
Molecular Weight 328.386
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of N-(6-METHOXY-8-QUINOLYL)-4-TOLUENESULFONAMIDE

SMILES

COC1=CC(NS(=O)(=O)C2=CC=C(C)C=C2)=C3N=CC=CC3=C1

InChI

InChIKey=HKRNYOZJJMFDBV-UHFFFAOYSA-N
InChI=1S/C17H16N2O3S/c1-12-5-7-15(8-6-12)23(20,21)19-16-11-14(22-2)10-13-4-3-9-18-17(13)16/h3-11,19H,1-2H3

HIDE SMILES / InChI

Molecular Formula C17H16N2O3S
Molecular Weight 328.386
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Zinc co-localizes with GABA and glycine in synapses in the lamprey spinal cord.
2001 Apr 30
Loss of vesicular zinc and appearance of perikaryal zinc after seizures induced by pilocarpine.
2001 May 25
Nitric oxide causes apparent release of zinc from presynaptic boutons.
2002
Modulation of energy metabolism in c6 glioma cells as possible mechanism contributing to zinc neurotoxicity.
2003
Role of metallothionein in regulating the abundance of histochemically reactive zinc in rat tissues.
2003 Aug
Clioquinol effects on tissue chelatable zinc in mice.
2003 Oct
Zinc release contributes to hypoglycemia-induced neuronal death.
2004 Aug
Influence of zinc deficiency on cell-membrane fluidity in Jurkat, 3T3 and IMR-32 cells.
2004 Mar 1
Measurement of presynaptic zinc changes in hippocampal mossy fibers.
2004 Nov 5
Tetanically released zinc inhibits hippocampal mossy fiber calcium, zinc and synaptic responses.
2005 Jun 14
Neurotoxic zinc translocation into hippocampal neurons is inhibited by hypothermia and is aggravated by hyperthermia after traumatic brain injury in rats.
2006 Feb
Changes in metallothionein levels in freshwater mussels exposed to urban wastewaters: effects from exposure to heavy metals?
2007 Mar 29
Role of zinc finger structure in nuclear localization of transcription factor Sp1.
2009 Feb 27
Secretory state regulates Zn2+ transport in gastric parietal cell of the rabbit.
2009 Oct
Zinc dyshomeostasis is linked with the loss of mucolipidosis IV-associated TRPML1 ion channel.
2010 Nov 5
Substance Class Chemical
Created
by admin
on Fri Dec 15 18:17:45 GMT 2023
Edited
by admin
on Fri Dec 15 18:17:45 GMT 2023
Record UNII
7SWW052N6R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
N-(6-METHOXY-8-QUINOLYL)-4-TOLUENESULFONAMIDE
Systematic Name English
TSQ [MI]
Common Name English
6-METHOXY-8-(P-TOLUENESULFONYL)AMINOQUINOLINE
Common Name English
TSQ
MI  
Common Name English
N-(6-METHOXY-8-QUINOLINYL)-4-METHYLBENZENESULFONAMIDE
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID00148996
Created by admin on Fri Dec 15 18:17:45 GMT 2023 , Edited by admin on Fri Dec 15 18:17:45 GMT 2023
PRIMARY
MESH
C061730
Created by admin on Fri Dec 15 18:17:45 GMT 2023 , Edited by admin on Fri Dec 15 18:17:45 GMT 2023
PRIMARY
WIKIPEDIA
TSQ
Created by admin on Fri Dec 15 18:17:45 GMT 2023 , Edited by admin on Fri Dec 15 18:17:45 GMT 2023
PRIMARY
CAS
109628-27-5
Created by admin on Fri Dec 15 18:17:45 GMT 2023 , Edited by admin on Fri Dec 15 18:17:45 GMT 2023
PRIMARY
PUBCHEM
130606
Created by admin on Fri Dec 15 18:17:45 GMT 2023 , Edited by admin on Fri Dec 15 18:17:45 GMT 2023
PRIMARY
MERCK INDEX
m11249
Created by admin on Fri Dec 15 18:17:45 GMT 2023 , Edited by admin on Fri Dec 15 18:17:45 GMT 2023
PRIMARY Merck Index
FDA UNII
7SWW052N6R
Created by admin on Fri Dec 15 18:17:45 GMT 2023 , Edited by admin on Fri Dec 15 18:17:45 GMT 2023
PRIMARY