Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C17H16N2O3S |
| Molecular Weight | 328.386 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC(NS(=O)(=O)C2=CC=C(C)C=C2)=C3N=CC=CC3=C1
InChI
InChIKey=HKRNYOZJJMFDBV-UHFFFAOYSA-N
InChI=1S/C17H16N2O3S/c1-12-5-7-15(8-6-12)23(20,21)19-16-11-14(22-2)10-13-4-3-9-18-17(13)16/h3-11,19H,1-2H3
| Molecular Formula | C17H16N2O3S |
| Molecular Weight | 328.386 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Loss of vesicular zinc and appearance of perikaryal zinc after seizures induced by pilocarpine. | 2001 May 25 |
|
| Imaging synaptic zinc release in living nervous tissue. | 2001 Sep 30 |
|
| Trans-synaptic increase of hypoxic tolerance in hippocampus upon physical challenge with two-photon microscopy. | 2002 |
|
| Nitric oxide causes apparent release of zinc from presynaptic boutons. | 2002 |
|
| Distribution of the zinc transporter ZnT-1 in comparison with chelatable zinc in the mouse brain. | 2002 Jun 3 |
|
| Mild hypothermia reduces zinc translocation, neuronal cell death, and mortality after transient global ischemia in mice. | 2002 Oct |
|
| Modulation of energy metabolism in c6 glioma cells as possible mechanism contributing to zinc neurotoxicity. | 2003 |
|
| Expression of P2X6, a purinergic receptor subunit, is affected by dietary zinc deficiency in rat hippocampus. | 2003 Jan |
|
| Tetanically released zinc inhibits hippocampal mossy fiber calcium, zinc and synaptic responses. | 2005 Jun 14 |
|
| Neurotoxic zinc translocation into hippocampal neurons is inhibited by hypothermia and is aggravated by hyperthermia after traumatic brain injury in rats. | 2006 Feb |
|
| Secretory state regulates Zn2+ transport in gastric parietal cell of the rabbit. | 2009 Oct |
|
| Zinc dyshomeostasis is linked with the loss of mucolipidosis IV-associated TRPML1 ion channel. | 2010 Nov 5 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:17:45 GMT 2023
by
admin
on
Fri Dec 15 18:17:45 GMT 2023
|
| Record UNII |
7SWW052N6R
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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DTXSID00148996
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C061730
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TSQ
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109628-27-5
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130606
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m11249
Created by
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7SWW052N6R
Created by
admin on Fri Dec 15 18:17:45 GMT 2023 , Edited by admin on Fri Dec 15 18:17:45 GMT 2023
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PRIMARY |