2-PHENYLIMIDAZOLE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H8N2
Molecular Weight	144.1732
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

N1C=CN=C1C2=CC=CC=C2

InChI

InChIKey=ZCUJYXPAKHMBAZ-UHFFFAOYSA-N

InChI=1S/C9H8N2/c1-2-4-8(5-3-1)9-10-6-7-11-9/h1-7H,(H,10,11)

HIDE SMILES / InChI

Molecular Formula	C9H8N2
Molecular Weight	144.1732
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Methyl 5'-(2-hy-droxy-phen-yl)-4',5',6',7'-tetra-hydro-spiro-[2H-1-benzopyran-2,7'-1,2,4-triazolo[1,5-a]pyrimidine]-3-carboxyl-ate.	2010-12-11	21522801
Electronic structure and (1)H NMR chemical shifts in host-guest complexes of cucurbit[6]uril and sym-tetramethyl cucurbit[6]uril with imidazole derivatives.	2010-10-14	20860350
Structural and biochemical characterization of the cytochrome P450 CypX (CYP134A1) from Bacillus subtilis: a cyclo-L-leucyl-L-leucyl dipeptide oxidase.	2010-08-31	20690619
Monastrol analogs: a synthesis of pyrazolopyridine, benzopyranopyrazolopyridine, and oxygen-bridged azolopyrimidine derivatives and their biological screening.	2010-07-15	20542426
Exploration of amino alcohol derivatives as novel, potent, and highly selective sphingosine-1-phosphate receptor subtype-1 agonists.	2010-04-15	20304639
Cotinine as a biomarker of tobacco exposure: development of a HPLC method and comparison of matrices.	2010-03	20155742
2-Phenyl-imidazolium chloride monohydrate.	2010-02-20	21580420
2-Phenyl-imidazolium acetate.	2010-02-17	21580402
2-Phenyl-imidazole dihydrogen phosphate phospho-ric acid.	2010-02-13	21580368
Glycosidase inhibition: assessing mimicry of the transition state.	2010-01-21	20066263
Bis(2-phenyl-1H-imidazole-κN)silver(I) nitrate.	2009-12-04	21579929
Biological reactive intermediates that mediate dacarbazine cytotoxicity.	2009-12	19399501
2-Phenyl-imidazolium nitrate monohydrate.	2009-11-28	21578976
Cytostatic factor proteins are present in male meiotic cells and beta-nerve growth factor increases mos levels in rat late spermatocytes.	2009-10-05	19802389
Molecular mechanisms of imidazole and benzene ring binding in proteins.	2009-08	19817694
Synthesis and evaluation of arylalkoxy- and biarylalkoxy-phenylamide and phenylimidazoles as potent and selective sphingosine-1-phosphate receptor subtype-1 agonists.	2009-04-15	19282175
Synthesis and evaluation of alkoxy-phenylamides and alkoxy-phenylimidazoles as potent sphingosine-1-phosphate receptor subtype-1 agonists.	2009-01-15	19081720
1-[2-(2,6-Dichloro-benz-yloxy)-2-(2-fur-yl)eth-yl]-1H-benzimidazole.	2008-07-09	21203152
Fluorescence spectroscopy and amplified spontaneous emission (ASE) of phenylimidazoles: predicted vibronic coupling along the excited-state intramolecular proton transfer in 2-(2'-hydroxyphenyl)imidazoles.	2008-06-26	18510296
Crystal structure of enoyl-acyl carrier protein reductase (FabK) from Streptococcus pneumoniae reveals the binding mode of an inhibitor.	2008-04	18305197
Autocatalytic demetalation of a Zn(salphen) complex provoked by unprotected N-heterocycles.	2008-02-14	18239827
Phenylimidazole derivatives as specific inhibitors of bacterial enoyl-acyl carrier protein reductase FabK.	2007-12-01	17892940
Phenylimidazole derivatives of 4-pyridone as dual inhibitors of bacterial enoyl-acyl carrier protein reductases FabI and FabK.	2007-09-20	17713898
Phenylimidazole derivatives as new inhibitors of bacterial enoyl-ACP reductase FabK.	2007-09-01	17600706
Biophysical characterization of the sterol demethylase P450 from Mycobacterium tuberculosis, its cognate ferredoxin, and their interactions.	2006-07-11	16819841
Exploring selectivity requirements for peripheral versus central benzodiazepine receptor binding affinity: QSAR modeling of 2-phenylimidazo[1,2-a]pyridine acetamides using topological and physicochemical descriptors.	2006-04	16955759
Substituent effects on enthalpies of formation of nitrogen heterocycles: 2-substituted benzimidazoles and related compounds.	2006-02-23	16480315
CG base pair recognition by substituted phenylimidazole nucleosides.	2004-04-21	15064798
Diversity synthesis via C-H bond functionalization: concept-guided development of new C-arylation methods for imidazoles.	2003-09-03	12940740
Novel imidazole compounds as a new series of potent, orally active inhibitors of 5-lipoxygenase.	2003-09-01	12927848
Genetic algorithm applied to the selection of factors in principal component-artificial neural networks: application to QSAR study of calcium channel antagonist activity of 1,4-dihydropyridines (nifedipine analogous).	2003-07-23	12870926
Induced fit process in the selective distal binding of imidazoles in zinc(II) porphyrin receptors.	2003-06-16	12793814
Selective C-arylation of free (NH)-heteroarenes via catalytic C-H bond functionalization.	2003-05-07	12720429
Quantitative structure-activity relationship study of recently synthesized 1,4-dihydropyridine calcium channel antagonists. Application of the Hansch analysis method.	2002-12	12506395
Alpha(1)-adrenoceptor antagonists. 4. Pharmacophore-based design, synthesis, and biological evaluation of new imidazo-, benzimidazo-, and indoloarylpiperazine derivatives.	2002-08-15	12166933
Solid-phase extraction and HPLC assay of nicotine and cotinine in plasma and brain.	2002	20597815
The historical aspects of sunscreens.	2001-11-15	11744395
Preparation, physicochemical characterization and pharmacological study of novel ruthenium(III) complexes with imidazole and benzimidazole derivatives.	2001-09	11642009

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 20:48:21 GMT 2025` Edited by `admin` on `Mon Mar 31 20:48:21 GMT 2025`
Record UNII	7R2590HM4L
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

CUREZOL 2PZ

Preferred Name

English

2-PHENYLIMIDAZOLE

Systematic Name

English

NSC-255226

Code

English

1H-IMIDAZOLE, 2-PHENYL-

Systematic Name

English

IMIDAZOLE, 2-PHENYL-

Systematic Name

English

2-PHENYL-1H-IMIDAZOLE

Systematic Name

English

Code System Code Type Description

NSC

255226