Approval Year
Substance Class |
Nucleic Acid
Created
by
admin
on
Edited
Sat Dec 16 14:19:12 GMT 2023
by
admin
on
Sat Dec 16 14:19:12 GMT 2023
|
Nucleic Acid Type | OLIGONUCLEOTIDE |
Nucleic Acid Subtype | |
Sequence Type | COMPLETE |
Record UNII |
7QI41X9QWC
|
Record Status |
Validated (UNII)
|
Record Version |
|
-
Download
Name | Type | Language | ||
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Official Name | English | ||
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Common Name | English | ||
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Code | English | ||
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Systematic Name | English | ||
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Common Name | English | ||
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Code | English | ||
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Code | English | ||
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Common Name | English |
Classification Tree | Code System | Code | ||
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FDA ORPHAN DRUG |
499215
Created by
admin on Sat Dec 16 14:19:12 GMT 2023 , Edited by admin on Sat Dec 16 14:19:12 GMT 2023
|
Code System | Code | Type | Description | ||
---|---|---|---|---|---|
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7QI41X9QWC
Created by
admin on Sat Dec 16 14:19:12 GMT 2023 , Edited by admin on Sat Dec 16 14:19:12 GMT 2023
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PRIMARY | |||
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C171741
Created by
admin on Sat Dec 16 14:19:12 GMT 2023 , Edited by admin on Sat Dec 16 14:19:12 GMT 2023
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PRIMARY | |||
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1709886-74-7
Created by
admin on Sat Dec 16 14:19:12 GMT 2023 , Edited by admin on Sat Dec 16 14:19:12 GMT 2023
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PRIMARY | |||
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11052
Created by
admin on Sat Dec 16 14:19:12 GMT 2023 , Edited by admin on Sat Dec 16 14:19:12 GMT 2023
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PRIMARY | |||
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HI-118
Created by
admin on Sat Dec 16 14:19:12 GMT 2023 , Edited by admin on Sat Dec 16 14:19:12 GMT 2023
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PRIMARY |
Sugar | Site Range | Site Count |
---|---|---|
Deoxyribose (DNA) | 1_6-1_15 | 10 / 20 |
2'-O-Methoxyethyl ribose | 1_1-1_5;1_16-1_20 | 10 / 20 |
Linkage | Site Range | Site Count |
---|---|---|
Phosporothioate | 1_2;1_6-1_17;1_20 | 14 / 19 |
Phosphate | 1_3-1_5;1_18-1_19 | 5 / 19 |
Related Record | Type | Details | ||
---|---|---|---|---|
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SALT/SOLVATE -> PARENT |
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Related Record | Type | Details | ||
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ACTIVE MOIETY |
Structural Modifications
Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
---|---|---|---|---|---|---|
NUCLEOSIDE_SUBSTITUTION | [1_9] [1_15] | SITE_SPECIFIC | 5-METHYLDEOXYCYTIDINE | B200GV71QM | ||
NUCLEOSIDE_SUBSTITUTION | [1_1] [1_3] [1_17] [1_18] [1_20] | SITE_SPECIFIC | 2'-O-(2-METHOXYETHYL)-5-METHYLCYTIDINE | AOQ54IZZ6J | ||
NUCLEOSIDE_SUBSTITUTION | [1_2] | SITE_SPECIFIC | 2'-O-(2-METHOXYETHYL)-5-METHYLURIDINE | 9Q36I4D9VB |