ALNUCTAMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 02:50:11 GMT 2025` Edited by `admin` on `Wed Apr 02 02:50:11 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	7OSV6M6T4D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ALNUCTAMAB

Official Name

English

alnuctamab [INN]

Preferred Name

English

ALNUCTAMAB [USAN]

Common Name

English

IMMUNOGLOBULIN G1-KAPPA/LAMBDA WITH DOMAIN CROSSOVER, ANTI-(HOMO SAPIENS TNFRSF17 (TNF RECEPTOR SUPERFAMILY MEMBER 17, TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 17, B CELL MATURATION ANTIGEN, BCMA, BCM, TNFRSF13A, CD269)) AND ANTI-(HOMO SAPIENS

Common Name

English

Alnuctamab [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

698119

Created by admin on Wed Apr 02 02:50:11 GMT 2025 , Edited by admin on Wed Apr 02 02:50:11 GMT 2025

Code System Code Type Description

SMS_ID

300000035038

Created by admin on Wed Apr 02 02:50:11 GMT 2025 , Edited by admin on Wed Apr 02 02:50:11 GMT 2025

PRIMARY

INN

11457

Created by admin on Wed Apr 02 02:50:11 GMT 2025 , Edited by admin on Wed Apr 02 02:50:11 GMT 2025

PRIMARY

FDA UNII

7OSV6M6T4D

Created by admin on Wed Apr 02 02:50:11 GMT 2025 , Edited by admin on Wed Apr 02 02:50:11 GMT 2025

PRIMARY

USAN

GH-171

Created by admin on Wed Apr 02 02:50:11 GMT 2025 , Edited by admin on Wed Apr 02 02:50:11 GMT 2025

PRIMARY

NCI_THESAURUS

C175740

Created by admin on Wed Apr 02 02:50:11 GMT 2025 , Edited by admin on Wed Apr 02 02:50:11 GMT 2025

PRIMARY

CAS

2296827-07-9

Created by admin on Wed Apr 02 02:50:11 GMT 2025 , Edited by admin on Wed Apr 02 02:50:11 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
1_143	1_199
2_143	2_199
1_219	3_216
1_450	2_225
1_453	2_228
1_578	2_348
1_252	1_320
1_368	1_424
1_485	1_545
1_591	1_649
1_444	5_232
2_219	4_216
2_260	2_320
2_366	2_424
3_136	3_196
3_23	3_89
4_136	4_196
4_23	4_89
5_152	5_212
5_22	5_98

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_521
N	2_296

Related Record Type Details


					PK6VHJAIBD

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17

TARGET->LIGAND

Amount:


					1U72JD9DDZ

T-CELL SURFACE GLYCOPROTEIN CD3 EPSILON CHAIN

TARGET -> ACTIVATOR

Amount:

Related Record Type Details


					7OSV6M6T4D

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_671] [2_446]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL