Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H22O6 |
| Molecular Weight | 334.3637 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=C(C[C@@H](O)C2=CC(OC)=C(OC)C(OC)=C2)C=C1O
InChI
InChIKey=LGZKGOGODCLQHG-CYBMUJFWSA-N
InChI=1S/C18H22O6/c1-21-15-6-5-11(8-14(15)20)7-13(19)12-9-16(22-2)18(24-4)17(10-12)23-3/h5-6,8-10,13,19-20H,7H2,1-4H3/t13-/m1/s1
| Molecular Formula | C18H22O6 |
| Molecular Weight | 334.3637 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
DescriptionCurator's Comment: Note: most of the information on combretastatin is in fact related to a combretastatin analog Combretastatin A4
Curator's Comment: Note: most of the information on combretastatin is in fact related to a combretastatin analog Combretastatin A4
Combretastatin is a phenol derivative isolated from the bark of Combretum caffrum, commonly known as South African Bush Willow. Combretastatin is an effective antimitotic agent, and like colchicine, inhibited tubulin polymerization and stimulated tubulin-dependent GTP hydrolysis.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:07:48 GMT 2025
by
admin
on
Mon Mar 31 19:07:48 GMT 2025
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| Record UNII |
7O62J06F18
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| Record Status |
Validated (UNII)
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| Record Version |
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-
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| Classification Tree | Code System | Code | ||
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NCI_THESAURUS |
C67421
Created by
admin on Mon Mar 31 19:07:48 GMT 2025 , Edited by admin on Mon Mar 31 19:07:48 GMT 2025
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| Code System | Code | Type | Description | ||
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100000089840
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DTXSID80897571
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DB12596
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Combretastatin
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SUB26305
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9895264
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7O62J06F18
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C80014
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C040105
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82855-09-2
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348103
Created by
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m3747
Created by
admin on Mon Mar 31 19:07:48 GMT 2025 , Edited by admin on Mon Mar 31 19:07:48 GMT 2025
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PRIMARY | Merck Index |