Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C18H22O6 |
| Molecular Weight | 334.3637 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=CC=C(C[C@@H](O)C2=CC(OC)=C(OC)C(OC)=C2)C=C1O
InChI
InChIKey=LGZKGOGODCLQHG-CYBMUJFWSA-N
InChI=1S/C18H22O6/c1-21-15-6-5-11(8-14(15)20)7-13(19)12-9-16(22-2)18(24-4)17(10-12)23-3/h5-6,8-10,13,19-20H,7H2,1-4H3/t13-/m1/s1
| Molecular Formula | C18H22O6 |
| Molecular Weight | 334.3637 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
DescriptionCurator's Comment: Note: most of the information on combretastatin is in fact related to a combretastatin analog Combretastatin A4
Curator's Comment: Note: most of the information on combretastatin is in fact related to a combretastatin analog Combretastatin A4
Combretastatin is a phenol derivative isolated from the bark of Combretum caffrum, commonly known as South African Bush Willow. Combretastatin is an effective antimitotic agent, and like colchicine, inhibited tubulin polymerization and stimulated tubulin-dependent GTP hydrolysis.
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 18:11:55 GMT 2023
by
admin
on
Fri Dec 15 18:11:55 GMT 2023
|
| Record UNII |
7O62J06F18
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Code | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
NCI_THESAURUS |
C67421
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
100000089840
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | |||
|
DTXSID80897571
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | |||
|
DB12596
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | |||
|
Combretastatin
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | |||
|
SUB26305
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | |||
|
9895264
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | |||
|
7O62J06F18
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | |||
|
C80014
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | |||
|
C040105
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | |||
|
82855-09-2
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | |||
|
348103
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | |||
|
m3747
Created by
admin on Fri Dec 15 18:11:55 GMT 2023 , Edited by admin on Fri Dec 15 18:11:55 GMT 2023
|
PRIMARY | Merck Index |