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Details

Stereochemistry ACHIRAL
Molecular Formula C8H5N3O4S
Molecular Weight 239.208
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of FANFT

SMILES

[O-][N+](=O)C1=CC=C(O1)C2=CSC(NC=O)=N2

InChI

InChIKey=ZQBWQLJJMGJREB-UHFFFAOYSA-N
InChI=1S/C8H5N3O4S/c12-4-9-8-10-5(3-16-8)6-1-2-7(15-6)11(13)14/h1-4H,(H,9,10,12)

HIDE SMILES / InChI

Molecular Formula C8H5N3O4S
Molecular Weight 239.208
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Tumor versus vascular photodamage in a rat tumor model.
1998-08-21
Effect of indomethacin on N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced urinary tract carcinogenesis.
1995-07
Liver NADPH-dependent oxidation of the 5-nitrofurans, FANFT and ANFT, by guinea pig and rat.
1993-02
Enhancement by phenothiazine and 2,5-di-O-acetyl-D-glucosaccharo-(1,4)(6,3)-dilactone of bladder carcinogenicity of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in rats.
1984-08
The Noble rat bladder cancer model. FANFT-induced tumors.
1984-03-01
Effect of aspirin on N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induced epithelial proliferation in the urinary bladder and forestomach of the rat.
1984-01
Inhibition by aspirin of N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide-induced bladder carcinogenesis and enhancement of forestomach carcinogenesis.
1984-01
A murine model for bladder cancer.
1984
Metastatic characteristics of four FANFT-induced murine bladder tumors.
1983-11
The influence of phenacetin or mechanical perforation on the development of renal pelvic and urinary bladder tumors in FANFT-induced urinary tract carcinogenesis.
1983-09
The use of a tumor colony assay in predicting chemotherapeutic drug response in murine bladder cancer.
1983-08-15
Effect of phenobarbital on the carcinogenesis of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide in rats.
1983-07
Long term dose response study of N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide-induced urinary bladder carcinogenesis.
1983-04
Cellular changes in rat urinary bladder carcinomas induced by FANFT: a quantitative electron microscopic analysis.
1983-03
Multistage carcinogenesis in the urinary bladder.
1983-03
Co-carcinogenicity of sodium saccharin and N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide for the urinary bladder.
1983
Keyhole-limpet haemocyanin (KLH) immunotherapy of murine transitional cell carcinoma.
1983
Expression of the cellular immune response during tumor development in an animal model of bladder cancer.
1982-12
Rat bladder isograft model for focal carcinoma.
1982-09
In vitro characterization of four N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide (FANFT) induced mouse bladder tumors.
1982-06
Time- and concentration-dependent inhibition of the clonogenic growth of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced murine bladder tumor cell lines by cis-diamminedichloroplatinum(II).
1982-03
Single and sequential combination intravesical chemotherapy of murine bladder cancer.
1982-02
Growth characteristics of N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide (FANFT)-induced mouse bladder tumor lines in a human tumor stem cell assay.
1982-01-15
Comparison between a purified and standard diet on FANFT-induced murine bladder cancer.
1981-11
Maintenance by saccharin of membrane alterations of rat bladder cells induced by subcarcinogenic treatment with bladder carcinogens.
1981-11
Aspirin inhibition of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced lesions of the urinary bladder correlated with inhibition of metabolism by bladder prostaglandin endoperoxide synthetase.
1981-09
Effect of L-tryptophan and sodium saccharin on urinary tract carcinogenesis initiated by N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
1981-08
Potentiation of dimethylhydrazine bowel carcinogenesis in rats.
1981-05-01
The effect of single dose N-methyl-N-nitrosourea on bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide in rats.
1981-05
13-cis-retinoic acid: effect on urinary bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide in Fischer rats.
1981-05
Synthetic retinamides: effect on urinary bladder carcinogenesis by FANFT in Fischer rats.
1981
Development of an in vitro and in vivo epithelial tumor model for the study of invasion.
1980-12
Effects of urine and continued exposure to carcinogen on progression of early neoplastic urinary bladder lesions.
1980-12
Induction of a transplantable urinary bladder carcinoma in dogs.
1980-07
Neovascularization in rats during urinary bladder carcinogenesis induced by N-[4-(5-Nitro-2-furyl)-2-thiazolyl]formamide.
1980-07
Early induction of mouse urinary bladder ornithine decarboxylase activity by rodent vesical carcinogens.
1980-06
Morphological effects of mitomycin C administered intravesically to normal mice and mice with N-[4-(5-nitro-2-furyl)-2-thiazolyl]-formamide-induce bladder neoplasms.
1980-02
Immunization by irradiated whole cells or cell extracts against an experimental bladder tumor.
1980-01
[Chemically induced transplantable carcinomas of the urinary bladder in dogs (author's transl)].
1980
[Epithelial bladder tumor induction in rats with N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide].
1980
Galactosyl transferase activity in rat bladder transitional cell carcinoma lines and in exfoliated cells in urine during carcinogenesis and reversible hyperplasia.
1980
Immunogenicity of N-[-4-(5-nitro-2-furyl)-2-thiazolyl]formamide-induced bladder cancer.
1978-12
Topography and numerical densities of intramembrane particles in chemical carcinogen-induced urinary bladder carcinomas in Fischer rats.
1978-12
Desmosome ultrastructure and biological behavior of chemical carcinogen-induced urinary bladder carcinomas.
1978-10
The pathogenesis of bladder cancer.
1977-11
A long-term study of reversible and progressive urinary bladder cancer lesions in rats fed N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide.
1977-08
Bacillus Calmette-Guérin and dinitrochlorobenzene immunotherapy of chemically induced bladder tumors.
1977-03
Reverse transcriptase inhibitors and chemically induced bladder tumors in mice.
1977-03
Uridine 5'-diphosphate galactose: glycoprotein galactosyl transferase activity in exfoliated bladder epithelial cells in rats fed N-(4-(5-nitro-2-furyl)-2-thiazolyl) formamide.
1977
Experimental bladder tumor induction, propagation, and therapy.
1976-07
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:42:03 GMT 2025
Edited
by admin
on Mon Mar 31 18:42:03 GMT 2025
Record UNII
7N99PZG62O
Record Status Validated (UNII)
Record Version
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Name Type Language
NSC-155010
Preferred Name English
FANFT
Common Name English
N-(4-(5-NITRO-2-FURYL)-2-THIAZOLYL)FORMAMIDE
Systematic Name English
N-(4-(5-NITRO-2-FURANYL)-2-THIAZOLYL)FORMAMIDE
Systematic Name English
Code System Code Type Description
PUBCHEM
32486
Created by admin on Mon Mar 31 18:42:03 GMT 2025 , Edited by admin on Mon Mar 31 18:42:03 GMT 2025
PRIMARY
FDA UNII
7N99PZG62O
Created by admin on Mon Mar 31 18:42:03 GMT 2025 , Edited by admin on Mon Mar 31 18:42:03 GMT 2025
PRIMARY
NSC
155010
Created by admin on Mon Mar 31 18:42:03 GMT 2025 , Edited by admin on Mon Mar 31 18:42:03 GMT 2025
PRIMARY
CAS
24554-26-5
Created by admin on Mon Mar 31 18:42:03 GMT 2025 , Edited by admin on Mon Mar 31 18:42:03 GMT 2025
PRIMARY
MESH
D005200
Created by admin on Mon Mar 31 18:42:03 GMT 2025 , Edited by admin on Mon Mar 31 18:42:03 GMT 2025
PRIMARY
EPA CompTox
DTXSID4020953
Created by admin on Mon Mar 31 18:42:03 GMT 2025 , Edited by admin on Mon Mar 31 18:42:03 GMT 2025
PRIMARY