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Details

Stereochemistry ACHIRAL
Molecular Formula 3Al.Na.2HO4P.4H2O.6H2O4P
Molecular Weight 949.8776
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SODIUM ALUMINIUM PHOSPHATE, ACIDIC

SMILES

O.O.O.O.[Na+].[Al+3].[Al+3].[Al+3].OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP([O-])([O-])=O.OP([O-])([O-])=O

InChI

InChIKey=IQQWMJSNEUUJAY-UHFFFAOYSA-D
InChI=1S/3Al.Na.8H3O4P.4H2O/c;;;;8*1-5(2,3)4;;;;/h;;;;8*(H3,1,2,3,4);4*1H2/q3*+3;+1;;;;;;;;;;;;/p-10

HIDE SMILES / InChI
Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Al
Molecular Weight 26.9815386
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula H3O4P
Molecular Weight 97.9952
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Kasal (Sodium Aluminum Phosphate, basic, non-leavening) is a white odorless powder comprised of an autogenous mixture of alkaline sodium aluminum phosphate and dibasic sodium phosphate. Kasal is used primarily as an emulsifier in the production of processed cheese.

CNS Activity

CNS Penetrant
2588
Curator's Comment: Aluminum can be detected in the brain of Kasal treated dogs.

Approval Year

1942
37
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release.
2007-04-15
Twenty-six week toxicity study with KASAL® (basic sodium aluminum phosphate) in beagle dogs.
1990-03
Toxicity and aluminium concentration in bone following dietary administration of two sodium aluminium phosphate formulations in rats.
1987-07
Patents

Patents

04565680
30
05123965
3
05414173
3
06613710
3
US3957679
3
US4166142A
3

Sample Use Guides

In Vivo Use Guide
Rats were fed control diet or diets containing 30,000 ppm KASAL for 28 days. Beagle dogs were fed diets containing up to 30,000 ppm KASAL for 26 weeks.
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 21:48:35 GMT 2025
Edited
by admin
on Mon Mar 31 21:48:35 GMT 2025
Record UNII
7N091Y877O
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SODIUM ALUMINIUM PHOSPHATE, ACIDIC
Common Name English
E 541
Preferred Name English
ALUMINIUM SODIUM PHOSPHATE
Systematic Name English
SODIUM ALUMINUM PHOSPHATE [HSDB]
Common Name English
SALP
Common Name English
ALUMINUM SODIUM PHOSPHATE
Systematic Name English
SODIUM ALUMINUM ORTHOPHOSPHATE
Systematic Name English
SODIUM ALUMINIUM PHOSPHATE, ACIDIC, TETRAHYDRATE
Common Name English
BUDAL 2308
Common Name English
SODIUM ALUMINUM PHOSPHATE, ACIDIC
Common Name English
PHOSPHORIC ACID, ALUMINUM SODIUM SALT
Common Name English
E-541(I)
Common Name English
INS NO.541(I)
Common Name English
INS-541(I)
Common Name English
Classification Tree Code System Code
CODEX ALIMENTARIUS (GSFA) INS-541(I)
Created by admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
JECFA EVALUATION INS-541(I)
Created by admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
Code System Code Type Description
PUBCHEM
72941495
Created by admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
PRIMARY
EPA CompTox
DTXSID80872525
Created by admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
PRIMARY
WIKIPEDIA
SODIUM ALUMINIUM PHOSPHATE
Created by admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
PRIMARY In addition to the usual hydrate, an anhydrous SAlP is also known, Na3H15Al2(PO4)8 (CAS#10279-59-1), referred to as 8:2:3, reflecting the ratio of phosphate to aluminium to sodium. Additionally an SAlP of ill-defined stoichiometry is used (NaxAly(PO4)z (CAS# 7785-88-8).[3]
CAS
7785-88-8
Created by admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
NON-SPECIFIC STOICHIOMETRY
CAS
10305-76-7
Created by admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
PRIMARY
SMS_ID
300000054585
Created by admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
PRIMARY
FDA UNII
7N091Y877O
Created by admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
PRIMARY
ECHA (EC/EINECS)
232-090-4
Created by admin on Mon Mar 31 21:48:35 GMT 2025 , Edited by admin on Mon Mar 31 21:48:35 GMT 2025
PRIMARY
NIH
NCATS
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