SODIUM ALUMINIUM PHOSPHATE, ACIDIC

US Approved OTC

First approved in 1942

Details

Stereochemistry	ACHIRAL
Molecular Formula	3Al.Na.2HO4P.4H2O.6H2O4P
Molecular Weight	949.8776
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of SODIUM ALUMINIUM PHOSPHATE, ACIDIC

Structure Search

SMILES

O.O.O.O.[Na+].[Al+3].[Al+3].[Al+3].OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP(O)([O-])=O.OP([O-])([O-])=O.OP([O-])([O-])=O

InChI

InChIKey=IQQWMJSNEUUJAY-UHFFFAOYSA-D

InChI=1S/3Al.Na.8H3O4P.4H2O/c;;;;8*1-5(2,3)4;;;;/h;;;;8*(H3,1,2,3,4);4*1H2/q3*+3;+1;;;;;;;;;;;;/p-10

HIDE SMILES / InChI

Molecular Formula	H3O4P
Molecular Weight	97.9952
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	HO
Molecular Weight	17.0073
Charge	-1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Na
Molecular Weight	22.9898
Charge	1
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Al
Molecular Weight	26.9815
Charge	3
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/24202578 | http://www.innophos.com/__sitedocs/msds/final-2kasal.pdf

Kasal (Sodium Aluminum Phosphate, basic, non-leavening) is a white odorless powder comprised of an autogenous mixture of alkaline sodium aluminum phosphate and dibasic sodium phosphate. Kasal is used primarily as an emulsifier in the production of processed cheese.

CNS Activity

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Toxicity and aluminium concentration in bone following dietary administration of two sodium aluminium phosphate formulations in rats.	1987 Jul	3623343
Twenty-six week toxicity study with KASAL® (basic sodium aluminum phosphate) in beagle dogs.	1990 Mar	24202578
Aluminum hydroxide adjuvants activate caspase-1 and induce IL-1beta and IL-18 release.	2007 Apr 15	17404311

Patents

Sample Use Guides

In Vivo Use Guide

Rats were fed control diet or diets containing 30,000 ppm KASAL for 28 days. Beagle dogs were fed diets containing up to 30,000 ppm KASAL for 26 weeks.

Route of Administration: Oral

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 07:59:40 GMT 2023` Edited by `admin` on `Sat Dec 16 07:59:40 GMT 2023`
Record UNII	7N091Y877O
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SODIUM ALUMINIUM PHOSPHATE, ACIDIC

Common Name

English

ALUMINIUM SODIUM PHOSPHATE

Systematic Name

English

SODIUM ALUMINUM PHOSPHATE [HSDB]

Common Name

English

SALP

Common Name

English

ALUMINUM SODIUM PHOSPHATE

Systematic Name

English

SODIUM ALUMINUM ORTHOPHOSPHATE

Systematic Name

English

SODIUM ALUMINIUM PHOSPHATE, ACIDIC, TETRAHYDRATE

Common Name

English

BUDAL 2308

Common Name

English

SODIUM ALUMINUM PHOSPHATE, ACIDIC

Common Name

English

PHOSPHORIC ACID, ALUMINUM SODIUM SALT

Common Name

English

E-541(I)

Common Name

English

E 541

Code

English

INS NO.541(I)

Common Name

English

INS-541(I)

Common Name

English

Classification Tree Code System Code

CODEX ALIMENTARIUS (GSFA)

INS-541(I)