COBALTOUS BROMIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	2Br.Co
Molecular Weight	218.741
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

SMILES

[Co++].[Br-].[Br-]

InChI

InChIKey=BZRRQSJJPUGBAA-UHFFFAOYSA-L

InChI=1S/2BrH.Co/h2*1H;/q;;+2/p-2

HIDE SMILES / InChI

Molecular Formula	BrH
Molecular Weight	80.912
Charge	0
Count	MOL RATIO 2 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	Co
Molecular Weight	58.9332
Charge	2
Count	MOL RATIO 1 MOL RATIO (average)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description

Cobaltous iodide is a catalyst used in organic synthesis.

Originator

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Hypoxia-inducible factor 1-alpha inhibitor 22	Inhibitor 8,297		1.0 µM [Ki]

Conditions

Condition	Modality	Highest Phase	Product
Unknown 2,578
Unknown 2,578
Unknown 2,578
Unknown 2,578
Unknown 2,578
Unknown 2,578
Unknown 2,578
Unknown 2,578
Unknown 2,578
Unknown 2,578
Unknown 2,578
Anemia 68	Primary	Withdrawn	Unknown

PubMed

Show entries

Title	Date	PubMed
Erythropoietic effect of cobalt in patients with or without anemia.	1949 May 12	18120180
Cobalt iontophoresis techniques for tracing afferent and efferent connections in the vertebrate CNS.	1975 May 2	1097054
Inhalation toxicity studies of cobalt sulfate in F344/N rats and B6C3F1 mice.	1990 Aug	2227161
Synthesis and Anti-Candida Activity of Cobalt(II) Complexes of Benzene-1,2-Dioxyacetic Acid (bdoaH(2)). X-Ray Crystal Structures of [Co(bdoa)(H(2)O)(3)] 3.5H(2)O and {[CO(phen)(3)](bdoa)}(2)24H(2)O (phen = 1,10-Phenanthroline).	1999	18475879
Determination of trace metal ions in common salt by stripping voltammetry.	1999 Nov-Dec	10589495

Showing 1 to 5 of 7 entries

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Patents

Sample Use Guides

In Vivo Use Guide

For treatment of anemia, oral cobal chloride was administered at doses 25 mg and 50 mg daily.

Route of Administration: Oral

In Vitro Use Guide

HIF asparaginyl hydroxylase activity was measured by a method based on the hydroxylation coupled decarboxylation of 2-oxoglutarate with the synthetic HIF-1α peptides in the presence of varying concentrations of Co (1-5 uM). Ki for HIF asparaginyl hydroxylase was 1uM.

Substance Class	Chemical
Record UNII	7M7RX75BAL
Record Status	`Validated (UNII)`
Record Version

Show entries

Name

Type

Language

COBALTOUS BROMIDE

Common Name

English

COBALT DIBROMIDE

Systematic Name

English

COBALTOUS BROMIDE [MI]

Common Name

English

COBALT DIBROMIDE [HSDB]

Common Name

English

COBALT(II) BROMIDE

Systematic Name

English

Showing 1 to 5 of 6 entries

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Show entries

Code System

Code

Type

Description

FDA UNII

7M7RX75BAL

PRIMARY

HSDB

998

PRIMARY

DAILYMED

7M7RX75BAL

PRIMARY

CAS

7789-43-7

PRIMARY

MERCK INDEX

m3689

PRIMARY

Merck Index

Showing 1 to 5 of 10 entries

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Show entries

Related Record

Type

Details


					AI1MR454XG

COBALTOUS CATION

PARENT -> SALT/SOLVATE

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