TROPOLONE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H6O2
Molecular Weight	122.1213
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC=CC=CC1=O

InChI

InChIKey=MDYOLVRUBBJPFM-UHFFFAOYSA-N

InChI=1S/C7H6O2/c8-6-4-2-1-3-5-7(6)9/h1-5H,(H,8,9)

HIDE SMILES / InChI

Molecular Formula	C7H6O2
Molecular Weight	122.1213
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Raman spectroscopic studies on tropolone complexes with La, Nd, Sm, Yb.	2006-07	16458049
The design of organic catalysis for epoxidation by hydrogen peroxide.	2006-07	16374624
The conformational state of polyphenol oxidase from field bean (Dolichos lablab) upon SDS and acid-pH activation.	2006-05-01	16393141
Preferential inhibition of the magnesium-dependent strand transfer reaction of HIV-1 integrase by alpha-hydroxytropolones.	2006-04	16418335
Searching for a new anti-HCV therapy: synthesis and properties of tropolone derivatives.	2006-03-10	16438939
High-resolution studies of tropolone in the S0 and S1 electronic states: isotope driven dynamics in the zero-point energy levels.	2006-02-21	16497038
Anticholinesterase efficiency of some tropolone alkaloids and their lumiderivatives.	2006-02-17	16480139
Isoelectronic homologues and isomers: tropolone, 5-azatropolone, 1-H-azepine-4,5-dione, saddle points, and ions.	2006-02-02	16435822
Human metallothionein gene expression is upregulated by beta-thujaplicin: possible involvement of protein kinase C and reactive oxygen species.	2006-01	16394509
Signal transduction and metabolic flux of beta-thujaplicin and monoterpene biosynthesis in elicited Cupressus lusitanica cell cultures.	2006-01	16242983
Arachidonate 12-lipoxygenases with reference to their selective inhibitors.	2005-12-09	16171776
Mosquito larvicidal activity of active constituent derived from Chamaecyparis obtusa leaves against 3 mosquito species.	2005-12	16506565
Effects of beta-thujaplicin on anti-Malassezia pachydermatis remedy for canine otitis externa.	2005-12	16397383
Prooxidant action of hinokitiol: hinokitiol-iron dependent generation of reactive oxygen species.	2005-12	16364055
Inhibitory effects of 4-n-butylresorcinol on tyrosinase activity and melanin synthesis.	2005-12	16327152
Efforts directed toward the synthesis of colchicine: application of palladium-catalyzed siloxane cross-coupling methodology.	2005-10-28	16238332
Determining the minimum number of detectable cardiac-transplanted 111In-tropolone-labelled bone-marrow-derived mesenchymal stem cells by SPECT.	2005-10-07	16177481
Potential antimalarial lead structures from fungi of marine origin.	2005-10	16254832
Sgk1, a cell survival response in neurodegenerative diseases.	2005-10	16125969
Total synthesis of (-)-colchicine via a Rh-triggered cycloaddition cascade.	2005-09-29	16178522
Oxidation of the flavonoid eriodictyol by tyrosinase.	2005-09	16289948
Role of cations and confinement in asymmetric photochemistry: enantio- and diastereo-selective photocyclization of tropolone derivatives within zeolites.	2005-08-21	16186938
The all-Cartesian reaction plane Hamiltonian: formulation and application to the H-atom transfer in tropolone.	2005-08-01	16108647
Polyphenol oxidase from Dominga table grape.	2005-07-27	16029000
Activation of catechol-O-methyltransferase in astrocytes stimulates homocysteine synthesis and export to neurons.	2005-07	15779086
18O effects on the infrared spectrum and skeletal tunneling of tropolone.	2005-06-08	15974672
Oxidative stress in plant cell culture: a role in production of beta-thujaplicin by Cupresssus lusitanica suspension culture.	2005-06-05	15834951
Six-coordinate titanium complexes of a tripodal aminetris(phenoxide) ligand: synthesis, structure, and dynamics.	2005-04-18	15819569
Benzotropolone inhibitors of estradiol methylation: kinetics and in silico modeling studies.	2005-04-01	15755652
Acaricidal activity of active constituent isolated in Chamaecyparis obtusa leaves against Dermatophagoides spp.	2005-03-23	15769116
Dynamical hydrogen atom tunneling in dichlorotropolone: a combined quantum, semiclassical, and classical study.	2005-03-22	15836378
Implications of comparative spectral doublets observed for neon-isolated and gaseous tropolone(OH) and tropolone(OD).	2005-03-22	15836375
Inhibition of LPS-stimulated NO production in mouse macrophage-like cells by tropolones.	2005-03-02	15736432
Ring expansion of sulfur substituted p-quinamines: regiospecific synthesis of 4-aminotropones.	2005-02-28	15719098
Methyl group rotation driven by proton transfer through a long-range chemical interaction.	2005-02-11	15651010
Characterization and purification of polyphenol oxidase from artichoke (Cynara scolymus L.).	2005-02-09	15686433
Fungal diversity from western redcedar fences and their resistance to beta-thujaplicin.	2005-02	15793620
Protection by tropolones against H2O2-induced DNA damage and apoptosis in cultured Jurkat cells.	2005-02	15763960
Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones.	2005	15741178
Biological activity of beta-dolabrin, gamma-thujaplicin, and 4-acetyltropolone, hinokitiol-related compounds.	2004-10	15467216
Polarization spectroscopy of gaseous tropolone in a strong electric field.	2004-09-08	15332888
Comparison of tropane alkaloid spectra between Datura innoxia grown in Egypt and Bulgaria.	2004-07-10	15241922
Cerebral neutrophil recruitment, histology, and outcome in acute ischemic stroke: an imaging-based study.	2004-07	15155970
Biological activity of alpha-thujaplicin, the isomer of hinokitiol.	2004-06	15187442
Cytotoxic activity of deferiprone, maltol and related hydroxyketones against human tumor cell lines.	2004-05-27	15161023
Jasmonate and ethylene signalling and their interaction are integral parts of the elicitor signalling pathway leading to beta-thujaplicin biosynthesis in Cupressus lusitanica cell cultures.	2004-05	15047767
Liquid chromatography-hydride generation-atomic absorption spectrometry for the speciation of tin in seafoods.	2004-04	15054533
Rotation-tunneling analysis of the origin band in the tropolone pi(*)<--pi absorption system.	2004-03-08	15267323
Time-dependent probability of quantum tunneling in terms of the quasisemiclassical method.	2004-03-08	15267315
(-)-Epigallocatechin-3-gallate and hinokitiol reduce melanin synthesis via decreased MITF production.	2004-03	15089040

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:37:08 GMT 2025` Edited by `admin` on `Mon Mar 31 17:37:08 GMT 2025`
Record UNII	7L6DL16P1T
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TROPOLONE

Official Name

English

NSC-89303

Preferred Name

English

2-HYDROXY-2,4,6-CYCLOHEPTATRIENE-1-ONE

Systematic Name

English

PURPUROCATECHOL

Common Name

English

TROPOLONE [MI]

Common Name

English

Tropolone [WHO-DD]

Common Name

English

2-HYDROXYTROPONE

Common Name

English

.ALPHA.-TROPOLONE

Common Name

English

2,4,6-CYCLOHEPTATRIEN-1-ONE, 2-HYDROXY-

Systematic Name

English

Code System Code Type Description

RXCUI

1368873