NAMINIDIL

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C15H19N5
Molecular Weight	269.3449
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

C[C@@H](N\C(NC#N)=N\C1=CC=C(C=C1)C#N)C(C)(C)C

InChI

InChIKey=PGYDRGZVXVVZQC-LLVKDONJSA-N

InChI=1S/C15H19N5/c1-11(15(2,3)4)19-14(18-10-17)20-13-7-5-12(9-16)6-8-13/h5-8,11H,1-4H3,(H2,18,19,20)/t11-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C15H19N5
Molecular Weight	269.3449
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	1
Optical Activity	UNSPECIFIED

Description
Sources: https://adisinsight.springer.com/drugs/800016162

Naminidil, a potassium channel opener, was under development with Bristol-Myers Squibb as a topical treatment for androgenetic alopecia. The research has been discontinued.

Originator

Approval Year

Patents

Sample Use Guides

In Vivo Use Guide

Topical application

Route of Administration: Topical

Substance Class	Chemical Created by `admin` on `Wed Apr 02 05:47:43 GMT 2025` Edited by `admin` on `Wed Apr 02 05:47:43 GMT 2025`
Record UNII	7K50VT05OD
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NAMINIDIL

Official Name

English

BMS-234303-01

Preferred Name

English

NAMINIDIL [USAN]

Common Name

English

naminidil [INN]

Common Name

English

N-CYANO-N'-(4-CYANOPHENYL)-N''-((1R)-1,2,2-TRIMETHYLPROPYL)GUANIDINE

Common Name

English

GUANIDINE, N-CYANO-N'-(4-CYANOPHENYL)-N''-((1R)-1,2,2-TRIMETHYLPROPYL)-

Systematic Name

English

NAMINIDIL, (R)-

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C29707