BROMODOMAIN-CONTAINING PROTEIN 3

Approval Year

Substance Class	Protein
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	7ISX4QDW6N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

KIAA0043

Preferred Name

English

BROMODOMAIN-CONTAINING PROTEIN 3

Common Name

English

RING3L

Common Name

English

RING3-LIKE PROTEIN

Common Name

English

BRD3

Common Name

English

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Code System

Code

Type

Description

FDA UNII

7ISX4QDW6N

PRIMARY

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Related Record

Type

Details


					O28XHZ9UQ4

ZEN-3694

INHIBITOR -> TARGET

Amount:


					5QIO6SRZ2R

MOLIBRESIB

INHIBITOR -> TARGET

Qualification:

Kd

Amount:

50.5 NANOMOLAR [40.6 to 60.4] (average)


					VR86R11J7J

MIVEBRESIB

INHIBITOR -> TARGET


					U4017GUQ06

PELABRESIB ANHYDROUS

INHIBITOR -> TARGET

Qualification:

IC50

Amount:

21 NANOMOLAR (average)


					X40LKS49S3

BIRABRESIB

INHIBITOR -> TARGET

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Structural Modifications

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Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_262] [1_280] [1_562]				DEXFOSFOSERINE	VI4F0K069V
AMINO ACID SUBSTITUTION	[1_1]				N-ACETYLSERINE	W98518XGZ3

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL

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