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Details

Stereochemistry ACHIRAL
Molecular Formula C10H13N5O
Molecular Weight 219.2431
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ZEATIN

SMILES

C\C(CO)=C/CNC1=NC=NC2=C1N=CN2

InChI

InChIKey=UZKQTCBAMSWPJD-FARCUNLSSA-N
InChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+

HIDE SMILES / InChI

Molecular Formula C10H13N5O
Molecular Weight 219.2431
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Description

Zeatin is a cytokinin plant growth factor, which has gerontomodulatory, youth preserving and anti-aging effects on serially passaged human adult skin fibroblasts undergoing aging in vitro.

Approval Year

Conditions

ConditionModalityTargetsHighest PhaseProduct

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Zeatin has gerontomodulatory, youth preserving and anti-aging effects on serially passaged human adult skin fibroblasts undergoing aging in vitro. There were no immediate negative or toxic effects in terms of cell attachment, cell proliferation, cell survival, cytoskeletal organization, and cellular growth by treatment with zeatin concentrations between 1 and 200 microM. During long-term treatment, cells could be maintained throughout their replicative lifespan in the presence of 40, 80, and 200 microM zeatin, but the optimal concentration of zeatin's anti-aging and youth-preserving effects was found to be 80 microM.
Substance Class Chemical
Record UNII
7I6OOJ9GR6
Record Status Validated (UNII)
Record Version