Stereochemistry | ABSOLUTE |
Molecular Formula | C6H11NO3S |
Molecular Weight | 177.221 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 2 / 2 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
N[C@@H](C[S@@+]([O-])CC=C)C(O)=O
InChI
InChIKey=XUHLIQGRKRUKPH-DYEAUMGKSA-N
InChI=1S/C6H11NO3S/c1-2-3-11(10)4-5(7)6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-,11-/m0/s1
Molecular Formula | C6H11NO3S |
Molecular Weight | 177.221 |
Charge | 0 |
Count |
MOL RATIO
1 MOL RATIO (average) |
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 1 / 1 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Alliin (S-allyl-l-cysteine sulfoxides, SACSO) is the major component of aged garlic extract, bearing broad-spectrum natural antioxidant properties. It was revealed, that alliin had an inhibitory effect in osteoclasteogenesis with a dose-dependent manner via blocking the c-Fos-NFATc1 signaling pathway and it could be a potential therapeutic agent for the treatment of osteoporosis. In addition, alliin ameliorates gut inflammation through MAPK-NF-κB/AP-1/STAT-1 inactivation and PPAR-γ activation.