Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H17N |
| Molecular Weight | 175.2701 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C(N1CCCCC1)C2=CC=CC=C2
InChI
InChIKey=NZVZVGPYTICZBZ-UHFFFAOYSA-N
InChI=1S/C12H17N/c1-3-7-12(8-4-1)11-13-9-5-2-6-10-13/h1,3-4,7-8H,2,5-6,9-11H2
| Molecular Formula | C12H17N |
| Molecular Weight | 175.2701 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Estrogenic effects and their action mechanism of the major active components of party pill drugs. | 2012-11-15 |
|
| Small molecule mimetics of an HIV-1 gp41 fusion intermediate as vaccine leads. | 2010-12-24 |
|
| Novel alkyl- and arylcarbamate derivatives with N-benzylpiperidine and N-benzylpiperazine moieties as cholinesterases inhibitors. | 2010-12 |
|
| Intramolecular NH···Pt interactions of platinum(II) diimine complexes with phenyl ligands. | 2010-11-01 |
|
| Hydride transfer reactions via ion-neutral complex: fragmentation of protonated N-benzylpiperidines and protonated N-benzylpiperazines in mass spectrometry. | 2010-05 |
|
| Neuroprotective and cholinergic properties of multifunctional glutamic acid derivatives for the treatment of Alzheimer's disease. | 2009-11-26 |
|
| Electrophoretically mediated microanalysis technique as a tool for the rapid screening of novel acetylcholinesterase inhibitors. | 2009-08-26 |
|
| Selective suppression of cocaine- versus food-maintained responding by monoamine releasers in rhesus monkeys: benzylpiperazine, (+)phenmetrazine, and 4-benzylpiperidine. | 2009-04 |
|
| Antiprion activity of functionalized 9-aminoacridines related to quinacrine. | 2008-07-15 |
|
| From rigid cyclic templates to conformationally stabilized acyclic scaffolds. Part II: Acyclic replacements for the (3S)-3-benzylpiperidine in a series of potent CCR3 antagonists. | 2008-01-15 |
|
| Zwitterionic (4-benzyl-piperidinium-1-yl-meth-yl)phospho-nate. | 2007-12-06 |
|
| Donepezil in Alzheimer's disease: From conventional trials to pharmacogenetics. | 2007-06 |
|
| Rewarding properties of 1-benzylpiperazine, a new drug of abuse, in rats. | 2006-04 |
|
| Is subnanomolar binding affinity required for the in vivo imaging of acetylcholinesterase? Studies on 18F-labeled G379. | 2006-01 |
|
| Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase. | 2005-12-15 |
|
| Human acetylcholinesterase inhibitors: electronic-topological and neural network approaches to the structure-activity relationships study. | 2005-05 |
|
| Discovery of melanin-concentrating hormone receptor R1 antagonists using high-throughput synthesis. | 2005-03-01 |
|
| Subtype selective NMDA receptor antagonists: evaluation of some novel alkynyl analogues. | 2004-03-08 |
|
| Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases. | 2003-11 |
|
| Structure-activity relationship studies of highly selective inhibitors of the dopamine transporter: N-benzylpiperidine analogues of 1-[2-[bis(4-fluorophenyl)methoxy]ethyl]-4-(3-phenylpropyl)piperazine. | 2003-04-10 |
|
| Syntheses and reactivities of disubstituted and trisubstituted fluorous pyridines with high fluorous phase affinities: solid state, liquid crystal, and ionic liquid-phase properties. | 2002-10-04 |
|
| Quaternary salts of E2020 analogues as acetylcholinesterase inhibitors for the reversal of neuromuscular block. | 2002-09-16 |
|
| NR2B selective NMDA receptor antagonists. | 2002 |
|
| [Application of neural networks using the volume learning algorithm for the study of structure-activity relationship in chemical compounds]. | 2001-09-18 |
|
| Design, synthesis, and structure-activity relationships of a series of 3-[2-(1-benzylpiperidin-4-yl)ethylamino]pyridazine derivatives as acetylcholinesterase inhibitors. | 2001-08-16 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Tue Apr 01 16:20:44 GMT 2025
by
admin
on
Tue Apr 01 16:20:44 GMT 2025
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| Record UNII |
7HZE16210B
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| Record Status |
Validated (UNII)
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| Record Version |
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