Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C5H5NO2 |
| Molecular Weight | 111.0987 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC=CNC1=O
InChI
InChIKey=GGOZGYRTNQBSSA-UHFFFAOYSA-N
InChI=1S/C5H5NO2/c7-4-2-1-3-6-5(4)8/h1-3,7H,(H,6,8)
| Molecular Formula | C5H5NO2 |
| Molecular Weight | 111.0987 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Pyrimidin-2(1H)-ones based inhibitors of Mycobacterium tuberculosis orotate phosphoribosyltransferase. | 2012-08 |
|
| Recent advances in the treatment of mucormycosis. | 2010-11 |
|
| Synthesis and iron sequestration equilibria of novel exocyclic 3-hydroxy-2-pyridinone donor group siderophore mimics. | 2010-09-20 |
|
| [Fungal diseases of vulva and vagina caused by Candida species]. | 2010-09 |
|
| Functional sorbents for selective capture of plutonium, americium, uranium, and thorium in blood. | 2010-09 |
|
| A novel pathway for nicotine degradation by Aspergillus oryzae 112822 isolated from tobacco leaves. | 2010-09 |
|
| The hydroxypyridinone iron chelator CP94 can enhance PpIX-induced PDT of cultured human glioma cells. | 2010-06-25 |
|
| Additive in vitro antiplasmodial effect of N-alkyl and N-benzyl-1,10-phenanthroline derivatives and cysteine protease inhibitor e64. | 2010 |
|
| Antineoplastic Activity of New Transition Metal Complexes of 6-Methylpyridine-2-carbaldehyde-N(4)-ethylthiosemicarbazone: X-Ray Crystal Structures of [VO(2)(mpETSC)] and [Pt(mpETSC)Cl]. | 2010 |
|
| Inhibition of HIV-1 gene expression by Ciclopirox and Deferiprone, drugs that prevent hypusination of eukaryotic initiation factor 5A. | 2009-10-13 |
|
| A distinct peripheral blood monocyte phenotype is associated with parasite inhibitory activity in acute uncomplicated Plasmodium falciparum malaria. | 2009-10 |
|
| Effects of point mutations in Plasmodium falciparum dihydrofolate reductase and dihydropterate synthase genes on clinical outcomes and in vitro susceptibility to sulfadoxine and pyrimethamine. | 2009-08-26 |
|
| Ethyl 5-[(1H-benzoimidazol-2-yl)amino-carbon-yl]-4-hydr-oxy-2-methyl-6-oxo-1-propyl-1,6-dihydro-pyridine-3-carboxyl-ate-ethanol-methanol (4/2/1). | 2009-07-25 |
|
| Amino-indanol catalyzed enantioselective reactions of 3-hydroxy-2-pyridones. | 2009-05-27 |
|
| Ruthenium-based metallacrown complexes for the selective detection of lithium ions in water and in serum by fluorescence spectroscopy. | 2009-03-21 |
|
| Metal-mediated base pairing within the simplified nucleic acid GNA. | 2009-02-07 |
|
| New tripodal hydroxypyridinone based chelating agents for Fe(III), Al(III) and Ga(III): Synthesis, physico-chemical properties and bioevaluation. | 2009-02 |
|
| Deferiprone glucuronidation by human tissues and recombinant UDP glucuronosyltransferase 1A6: an in vitro investigation of genetic and splice variants. | 2009-02 |
|
| 1,2-hydroxypyridonate/terephthalamide complexes of gadolinium(III): synthesis, stability, relaxivity, and water exchange properties. | 2009-01-05 |
|
| Metal-ligand solution equilibria studied by electrospray ionization mass spectrometry: effect of instrumental parameters. | 2009-01 |
|
| Conformational tuning of magnetic interactions in metal-DNA complexes. | 2009 |
|
| Structural origin of copper ion containing artificial DNA: a density functional study. | 2008-12-25 |
|
| Mononuclear metal complexes with ciprofloxacin: Synthesis, characterization and DNA-binding properties. | 2008-09 |
|
| Duplex structure of a minimal nucleic acid. | 2008-07-02 |
|
| Breaking the symmetry: assembly of cylindrical nanostructures with a C3-symmetrical ligand. | 2008-06-02 |
|
| Basic 3-hydroxypyridin-4-ones: potential antimalarial agents. | 2008-05 |
|
| Dioxidobis(2-oxo-1,2-dihydropyridin-3-olato)-molybdenum(VI). | 2008-03-29 |
|
| Terephthalamide-containing ligands: fast removal of iron from transferrin. | 2008-02 |
|
| 3-Hydroxypyridin-2-one complexes of near-infrared (NIR) emitting lanthanides: sensitization of holmium(III) and praseodymium(III) in aqueous solution. | 2008 |
|
| Synthesis, Spectroscopic, and Anticancerous Properties of Mixed Ligand Palladium(II) and Silver(I) Complexes with 4,6-Diamino-5-hydroxy-2-mercaptopyrimidine and 2,2'-Bipyridyl. | 2008 |
|
| Deferiprone in the treatment of transfusion-dependent thalassemia: a review and perspective. | 2007-10 |
|
| Direct comparison of delta-aminolevulinic acid and methyl-aminolevulinate-derived protoporphyrin IX accumulations potentiated by desferrioxamine or the novel hydroxypyridinone iron chelator CP94 in cultured human cells. | 2007-06-20 |
|
| Multicomponent assembly of boron-based dendritic nanostructures. | 2007-03-16 |
|
| Metal complexes with the quinolone antibacterial agent N-propyl-norfloxacin: synthesis, structure and bioactivity. | 2007-03 |
|
| FT-IR, FT-Raman spectra and scaled quantum mechanical study of 2,3-dihydroxy pyridine and 2,4-dihyroxy-3-nitropyridine. | 2006-11 |
|
| Novel, efficient total synthesis of natural 20(S)-camptothecin. | 2006-10-21 |
|
| Model complexes of cobalt-substituted matrix metalloproteinases: tools for inhibitor design. | 2006-09-04 |
|
| Bridged dihydroxypyridine ligands for the synthesis of expanded helicates. | 2006-08-16 |
|
| Fe(III)-templated Gd(III) self-assemblies-a new route toward macromolecular MRI contrast agents. | 2006-07-26 |
|
| Iron binding dendrimers: a novel approach for the treatment of haemochromatosis. | 2006-07-13 |
|
| Synthesis and thermodynamic evaluation of mixed hexadentate linear iron chelators containing hydroxypyridinone and terephthalamide units. | 2006-05-01 |
|
| Concise synthesis of 22-hydroxyacuminatine, cytotoxic camptothecinoid from Camptotheca acuminata, by pyridone benzannulation. | 2006-02-07 |
|
| Utilization of self-sorting processes to generate dynamic combinatorial libraries with new network topologies. | 2006-01-23 |
|
| Bifunctional 3-hydroxy-4-pyridinone derivatives as potential pharmaceuticals: synthesis, complexation with Fe(III), Al(III) and Ga(III) and in vivo evaluation with 67Ga. | 2005-08 |
|
| A novel, expeditious synthesis of racemic camptothecin. | 2005-07-07 |
|
| Coordination behavior toward copper(II) and zinc(II) ions of three ligands joining 3-hydroxy-2-pyridinone and polyaza fragments. | 2005-05-02 |
|
| Oxygen accessibility and iron levels are critical factors for the antifungal action of ciclopirox against Candida albicans. | 2005-05 |
|
| Hydroxypyridinone functionalized self-assembled monolayers on nanoporous silica for sequestering lanthanide cations. | 2005-04 |
|
| Study of metal complexes of a tripodal hydroxypyridinone ligand by electrospray tandem mass spectrometry. | 2005 |
|
| Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii. | 1994-08-17 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 19:10:52 GMT 2025
by
admin
on
Mon Mar 31 19:10:52 GMT 2025
|
| Record UNII |
7HY4BCJ130
|
| Record Status |
Validated (UNII)
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| Record Version |
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