PROPYLHEXEDRINE HYDROCHLORIDE, (R)-

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C10H21N.ClH
Molecular Weight	191.741
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PROPYLHEXEDRINE HYDROCHLORIDE, (R)-

Structure Search

SMILES

Cl.CN[C@H](C)CC1CCCCC1

InChI

InChIKey=WLEGHNSHAIHZPS-SBSPUUFOSA-N

InChI=1S/C10H21N.ClH/c1-9(11-2)8-10-6-4-3-5-7-10;/h9-11H,3-8H2,1-2H3;1H/t9-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C10H21N
Molecular Weight	155.2804
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.drugs.com/monograph/benzedrex.html | https://www.ncbi.nlm.nih.gov/pubmed/20295519

D-propylhexedrine is an optical isomer of propylhexedrine, a vasoconstrictor stimulating α-adrenergic receptors of the sympathetic nervous system. D-propylhexedrine is proposed to be less potent isomer, it is is less pressor and less excitatory on the central nervous system than is the L-isomer.

CNS Activity

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Adrenergic receptor alpha 64 Target ID: CHEMBL2095203 Sources: https://books.google.com/books?id=OWFiVaDZnkQC&printsec=frontcover&hl=ru#v=onepage&q&f=false	Agonist 2678

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
The pharmacologic activity of N-methyl-beta-cyclohexyl-isopropylamine hydrochloride.	1947 Apr	20295519

Sample Use Guides

In Vivo Use Guide

rats: 20 mg/kg

Route of Administration: Intraperitoneal

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Sat Dec 16 10:10:13 GMT 2023` Edited by `admin` on `Sat Dec 16 10:10:13 GMT 2023`
Record UNII	7H29A4132J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PROPYLHEXEDRINE HYDROCHLORIDE, (R)-

Common Name

English

(+)-PROPYLHEXEDRINE HYDROCHLORIDE

Common Name

English

PROPYLHEXEDRINE HYDROCHLORIDE, (+)-

Common Name

English

CYCLOHEXANEETHANAMINE, N,.ALPHA.-DIMETHYL-, HYDROCHLORIDE (R)-

Systematic Name

English

PROPYLHEXEDRINE D-FORM HYDROCHLORIDE [MI]

Common Name

English

Code System Code Type Description

CAS

6192-96-7